Downregulation of Rv0189c, encoding a dihydroxyacid dehydratase, affects growth of Mycobacterium tuberculosis in vitro and in mice

Microbiology

Volumn 157, Issue 1, 2011, Pages 38-46

  Singh, Vinayak ^a   Chandra, Deepak ^b   Srivastava, Brahm S ^a   Srivastava, Ranjana ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b UNIVERSITY OF LUCKNOW   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; DIHYDROXYACID DEHYDRATASE; ISOLEUCINE; LEUCINE; MESSENGER RNA; NITRIC OXIDE; UNCLASSIFIED DRUG; VALINE;

ACIDITY; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUXOTROPHIC MUTANT; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BACTERIAL VIABILITY; BACTERIUM MUTANT; BACTERIUM TRANSFORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE DISRUPTION; GENE INACTIVATION; GENE OVEREXPRESSION; GENETIC COMPLEMENTATION; ILVD GENE; IN VITRO STUDY; INTRON; LUNG TUBERCULOSIS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; UPREGULATION;

AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; BACTERIAL PROTEINS; CLONING, MOLECULAR; CULTURE MEDIA; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ESCHERICHIA COLI; GENE DELETION; GENE EXPRESSION; GENE SILENCING; GENETIC COMPLEMENTATION TEST; HYDRO-LYASES; LUNG; MICE; MICE, INBRED BALB C; MYCOBACTERIUM TUBERCULOSIS; NITRIC OXIDE; PROTEIN MULTIMERIZATION; TUBERCULOSIS, PULMONARY; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA; MUS; MYCOBACTERIUM TUBERCULOSIS;

EID: 78650720071     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.042358-0     Document Type: Article

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