Iron-cofactored superoxide dismutase inhibits host responses to Mycobacterium tuberculosis

American Journal of Respiratory and Critical Care Medicine

Volumn 164, Issue 12, 2002, Pages 2213-2219

  Edwards, Kathryn M ^a,b   Cynamon, Michael H ^a,b   Voladri, Rama K R ^a,b   Hager, Cynthia C ^a,b   Destefano, Michelle S ^a,b   Tham, Kyi T ^a,b   Lakey, David L ^a,b   Bochan, Markian R ^a,b   Kernodle, Douglas S ^a,b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Superoxide dismutase; Tuberculosis

Indexed keywords

IRON; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL MUTATION; BACTERIUM ISOLATE; CELL INFILTRATION; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; INFLAMMATION; LUNG TUBERCULOSIS; MONONUCLEAR CELL; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SPLEEN; WEIGHT GAIN;

EID: 0037114195     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.164.12.2106093     Document Type: Article

References (65)

1. Modeling the impact of global tuberculosis control strategies
2. Attenuation of virulence by disruption of the Mycobacterium tuberculosis erp gene
3. Construction and characterization of a Mycobacterium tuberculosis mutant lacking the alternate sigma factor gene, sigF
4. A novel mycolic acid cyclopropane synthetase is required for coding, persistence, and virulence of Mycobacterium tuberculosis
5. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
6. Auxotrophic vaccines for tuberculosis
7. Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis
8. Persistence and protective efficacy of a Mycobacterium tuberculosis auxotroph vaccine
9. Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates
10. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
11. Virulent Salmonella typhimurium has two periplasmic Cu, Zn-superoxide dismutases
12. Rational live oral carrier vaccine design by mutating virulence-associated genes of Yersinia enterocolitica
13. The iron superoxide dismutase of Legionella pneumophila is essential for viability
14. Genetic analysis of superoxide dismutase, the 23 kilodalton antigen of Mycobacterium tuberculosis
15. Cu,Zn superoxide dismutase of Mycobacterium tuberculosis contributes to survival in activated macrophages that are generating an oxidative burst
16. Export of recombinant Mycobacterium tuberculosis superoxide dismutase is dependent upon both information in the protein and mycobacterial export machinery. A model for studying export of leaderless proteins by pathogenic mycobacteria
17. Role of Mycobacterium tuberculosis copper-zinc superoxide dismutase
18. The uraA locus and homologous recombination in Mycobacterium bovis BCG
19. A rapid method for screening antimicrobial agents for activities against a strain of Mycobacterium tuberculosis expressing firefly luciferase
20. Enhanced production of recombinant Mycobacterium tuberculosis antigens in Escherichia coli by replacement of low-usage codons
21. Green fluorescent protein as a marker for gene expression and cell biology of mycobacterial interactions with macrophages
22. Mouse model of tuberculosis
23. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
24. Isolation of superoxide dismutase mutants in Escherichia coli: Is superoxide dismutase necessary for aerobic life?
25. Pseudomonas aeruginosa sodA and sodB mutants defective in manganese- and iron-cofactored superoxide dismutase activity demonstrate the importance of the iron-cofactored form in aerobic metabolism
26. The sodA gene of Haemophilus ducreyi encodes a hydrogen peroxide-inhibitable superoxide dismutase
27. Conditionally replicating mycobacteriophages: A system for transposon delivery to Mycobacterium tuberculosis
28. Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis
29. Use of a flexible cassette method to generate a double unmarked Mycobacterium tuberculosis tlyA plcABC mutant by gene replacement
30. The use of RNAs complementary to specific mRNAs to regulate the expression of individual bacterial genes
31. Expression of an antisense hla fragment in Staphylococcus aureus reduces α-toxin production in vitro and attenuates lethal activity in a murine model
32. Development and use of a conditional antisense mutagenesis system in mycobacteria
33. Antisense RNA to ahpC, an oxidative stress defence gene involved in isoniazid resistance, indicates that AhpC of Mycobacterium bovis has virulence properties
34. Redox signaling and the control of cell growth and death
35. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages
36. Entry of Mycobacterium tuberculosis into mononuclear phagocytes
37. Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium tuberculosis
38. Cytosolic phospholipase A2 participates with TNF-alpha in the induction of apoptosis of human macrophages infected with Mycobacterium tuberculosis H37Ra
39. Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin
40. Fas/FasL-dependent apoptosis of alveolar cells after lipopolysaccharide-induced lung injury in mice
41. The role of superoxide radical in TNF-α induced NF-κB activation
42. Reactive oxygen intermediates as mediators of programmed cell death in plants and animals
43. Adenoviral gene delivery can inactivate Kupffer cells: Role of oxidants in NF-κB activation and cytokine production
44. Overexpression of CuZn superoxide dismutase protects RAW 264.7 macrophages against nitric oxide cytotoxicity
45. Overexpression of manganese superoxide dismutase gene suppresses spontaneous apoptosis without a resultant alteration in in vivo growth of the mouse fibrosarcoma, FSa-II
46. Activation of NF-κB in Mycobacterium tuberculosis-induced interleukin-2 receptor expression in mononuclear phagocytes
47. Effect of in vitro infection of human monocytes with low numbers of Mycobacterium tuberculosis bacteria on monocyte apoptosis
48. Lipoarabinomannans derived from different strains of Mycobacterium tuberculosis differentially stimulate the activation of NF-κB and KBF1 in murine macrophages
49. Role of caspases and NF-κB signaling in hydrogen peroxide- and superoxide-induced hepatocyte apoptosis
50. Activation of NF-κB protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration
51. Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis
52. Differential effects of a toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses
53. The apoptotic signaling pathway activated by Toll-like receptor-2
54. Antioxidants differentially regulate activation of nuclear factor-κB, activator protein-1, c-Jun amino-terminal kinases, and apoptosis induced by tumor necrosis factor: Evidence that JNK and NF-κB activation are not linked to apoptosis
55. Superoxide dismutase activity of Mycobacterium tuberculosis isolated from tuberculosis patients and the immunoreactivity of superoxide dismutase from M. tuberculosis H37Rv
56. Extracellular enzyme activities potentially involved in the pathogenicity of Mycobacterium tuberculosis
57. Comparative analysis of subcellular distribution of protein antigens in Mycobacterium bovis bacillus Calmette-Guerin
58. The role of macrophage cell death in tuberculosis
59. Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages
60. Toxoplasma gondii-infected cells are resistant to multiple inducers of apoptosis
61. Intracellular infection by Leishmania donovani inhibits macrophage apoptosis
62. Hijacking of apoptotic pathways by bacterial pathogens
63. Inhibition of apoptosis in chlamydia-infected cells: Blockade of mitochondrial cytochrome c release and caspase activation
64. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-κB and activated protein-1