Anaphase-promoting complex/cyclosome controls HEC1 stability

Cell Proliferation

Volumn 44, Issue 1, 2011, Pages 1-9

  Li, L ^a,b   Zhou, Y ^c   Wang, G F ^a   Liao, S C ^b   Ke, Y B ^b   Wu, W ^b   Li, X H ^b   Zhang, R L ^b   Fu, Y C ^a  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b SHENZHEN CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CHROMOSOME PROTEIN; CYCLIN B; PROTEASOME; PROTEIN HEC 1; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE PROGRESSION; CHROMOSOME STRUCTURE; EMBRYO; HUMAN; HUMAN CELL; IN VIVO STUDY; MITOSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; RNA INTERFERENCE; UBIQUITINATION;

CADHERINS; CELL NUCLEUS; HUMANS; KINETOCHORES; MITOSIS; MUTATION; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA INTERFERENCE; RNA, SMALL INTERFERING; SUBSTRATE SPECIFICITY; TRANSFECTION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASE COMPLEXES;

EID: 78650697902     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2010.00712.x     Document Type: Article

References (31)

1. Asbury CL, Trisha ND (2008) Insights into the kinetochore. Structure 16, 834-836.
2. Yoon HJ, Carbon J (1995) Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme. Mol. Cell. Biol. 15, 4835-4842.
3. Yamamoto TM, Iwabuchi M, Ohsumi K, Kishimoto T (2005) APC/C-Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs. Dev. Biol. 279, 345-355.
4. Stewart S, Fang G (2005) Destruction box-dependent degradation of aurora B is mediated by the anaphase-promoting complex/cyclosome and Cdh. Cancer Res. 65, 8730-8735.
5. Seki A, Fang G (2007) CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit. J. Biol. Chem. 282, 15103-15113.
6. Hershko A, Ciechanover A (1998) The ubiquitin system. Annu. Rev. Biochem. 67, 425-479.
7. Stewart S, Fang G (2005) Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit. Mol. Cell. Biol. 25, 10516-10527.
8. Chen RH (2007) Dual inhibition of Cdc20 by the spindle checkpoint. J. Biomed. Sci. 14, 475-479.
9. Jaspersen SL, Charles JF, Morgan DO (1999) Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14. Curr. Biol. 9, 227-236.
10. Kramer ER, Gieffers C, Hölzl G, Hengstschläger M, Peters JM (1998) Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family. Curr. Biol. 8, 1207-1210.
11. Pfleger CM, Kirschner MW (2000) The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev. 14, 655-665.
12. Lin YT, Chen Y, Wu G, Lee WH (2006) Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control. Oncogene 25, 1-14.
13. Chen Y, Riley DJ, Zheng L, Chen PL, Lee WH (2002) Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation. J. Biol. Chem. 277, 49408-49416.
14. Hori T, Haraguchi T, Hiraoka Y, Kimura H, Fukagawa T (2003) Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells. J. Cell Sci. 116, 3347-3362.
15. Vorozhko VV, Emanuele MJ, Kallio MJ, Stukenberg PT, Gorbsky GJ (2008) Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin. Chromosoma 117, 169-179.
16. Ciferri C, Deluca J, Monzani S, Ferrari KJ, Ristic D, Wyman C et al. (2005) Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore. J. Biol. Chem. 280, 29088-29095.
17. Diaz-Rodríguez E, Sotillo R, Schvartzman JM, Benezra R (2008) Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo. Proc. Natl. Acad. Sci. USA 105, 16719-16724.
18. Chen L, Li L, Qiao X, Liu J, Yao X (2007) Functional characterization of the promoter of human kinetochore protein HEC1: novel link between regulation of the cell cycle protein and CREB family transcription factors. Biochim. Biophys. Acta 1769, 593-602.
19. Zhang Y, Xiong Y (2001) A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation. Science 292, 1910-1915.
20. Bharadwaj R, Yu R (2004) The spindle checkpoint, aneuploidy, and cancer. Oncogene 23, 2016-2027.
21. Normand G, Hemmati PG, Verdoodt B, von Haefen C, Wendt J, Guner D et al. (2005) p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity. J. Biol. Chem. 280, 7118-7130.
22. Franks DJ, Mroske C, Laneuville O (2001) A fluorescence microscopy method for quantifying levels of prostaglandin endoperoxide H synthase-1 and CD-41 in MEG-01 cells. Biol. Proced. Online 3, 54-63.
23. Li L, Deng B, Xing G, Teng Y, Tian C, Yin X et al. (2007) PACT is a negative regulator of p53 and essential for cell growth and embryonic development. Proc Natl. Acad. Sci. USA 104, 7951-7956.
24. Listovsky T, Oren YS, Yudkovsky Y, Mahbubani HM, Weiss AM, Lebendiker M et al. (2004) Mammalian Cdh1/Fzr mediates its own degradation. EMBO J. 23, 1619-1626.
25. Tsai YV, Qi H, Lin CP, Lin RK, Kerrigan JE, Rzuczek SG et al. (2009) A G-quadruplex stabilizer induces M phase cell cycle arrest. J. Biol. Chem. 284, 22535-22543.
26. Xiao CW, Yan X, Li Y, Reddy SA, Tsang BK (2003) Resistance of human ovarian cancer cells to tumor necrosis factor alpha is a consequence of nuclear factor kappaB-mediated induction of Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory protein. Endocrinology 144, 623-630.
27. Oka M, Yanagewa Y, Asada T, Yoneda A, Hasezawa S, Sato T et al. (2004) Inhibition of proteasome by MG-132 treatment causes extra phragmoplast formation and cortical microtubule disorganization during M/G1 transition in synchronized tobacco cells. Plant Cell Physiol. 45, 1623-1632.
28. Burton JL, Solomon MJ (2001) D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p. Genes Dev. 15, 2381-2395.
29. Chen Y, Sharp ZD, Lee WH (1997) HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins. J. Biol. Chem. 272, 24081-24087.
30. Rimmington G, Dalby B, Glover DM (1994) Expression of N-terminally truncated cyclin B in the Drosophila larval brain leads to mitotic arrest at late anaphase. J. Cell Sci. 107, 2729-2738.
31. Kraft C, Herzog F, Gieffers C, Mechtler K, Hagting A, Pines J et al. (2003) Mitotic regulation of the human anaphase-promoting complex by phosphorylation. EMBO J. 22, 6598-6609.