Functional characterization of the promoter of human kinetochore protein HEC1: Novel link between regulation of the cell cycle protein and CREB family transcription factors

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1769, Issue 9-10, 2007, Pages 593-602

  Cheng, Liansheng ^a   Li, Liangwei ^a   Qiao, Xinxian ^a   Liu, Jing ^a   Yao, Xuebiao ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

ATF4; CREB; HEC1; Kinetochore; Promoter

Indexed keywords

CELL CYCLE PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROTEIN DERIVATIVE; PROTEIN HEC1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CENTROMERE; CONTROLLED STUDY; DNA FLANKING REGION; DOWN REGULATION; GENE CONSTRUCT; GENE DELETION; GENE MUTATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ACTIVATING TRANSCRIPTION FACTOR 4; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOWN-REGULATION; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; KINETOCHORES; MUTATION; NUCLEAR PROTEINS; RESPONSE ELEMENTS; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 34548642081     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbaexp.2007.07.005     Document Type: Article

References (41)

1. Storchova Z., and Pellman D. From polyploidy to aneuploidy, genome instability and cancer. Nat. Rev., Mol. Cell Biol. 5 (2004) 45-54
2. Cleveland D.W., Mao Y., and Sullivan K.F. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell 112 (2003) 407-421
3. Hori T., Haraguchi T., Hiraoka Y., Kimura H., and Fukagawa T. Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells. J. Cell Sci. 116 (2003) 3347-3362
4. Durfee T., Becherer K., Chen P.L., Yeh S.H., Yang Y., Kilburn A.E., Lee W.H., and Elledge S.J. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7 (1993) 555-569
5. DeLuca J.G., Moree B., Hickey J.M., Kilmartin J.V., and Salmon E.D. hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells. J. Cell Biol. 159 (2002) 549-555
6. Chen Y., Riley D.J., Chen P.L., and Lee W.H. HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis. Mol. Cell. Biol. 17 (1997) 6049-6056
7. Wigge P.A., Jensen O.N., Holmes S., Soues S., Mann M., and Kilmartin J.V. Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J. Cell Biol. 141 (1998) 967-977
8. Nabetani A., Koujin T., Tsutsumi C., Haraguchi T., and Hiraoka Y. A conserved protein, Nuf2, is implicated in connecting the centromere to the spindle during chromosome segregation: a link between the kinetochore function and the spindle checkpoint. Chromosoma 110 (2001) 322-334
9. Martin-Lluesma S., Stucke V.M., and Nigg E.A. Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science 297 (2002) 2267-2270
10. Ciferri C., De Luca J., Monzani S., Ferrari K.J., Ristic D., Wyman C., Stark H., Kilmartin J., Salmon E.D., and Musacchio A. Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore. J. Biol. Chem. 280 (2005) 29088-29095
11. DeLuca J.G., Dong Y., Hergert P., Strauss J., Hickey J.M., Salmon E.D., and McEwen B.F. Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites. Mol. Biol. Cell 16 (2005) 519-531
12. DeLuca J.G., Howell B.J., Canman J.C., Hickey J.M., Fang G., and Salmon E.D. Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores. Curr. Biol. 13 (2003) 2103-2109
13. Chen Y., Riley D.J., Zheng L., Chen P.L., and Lee W.H. Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation. J. Biol. Chem. 277 (2002) 49408-49416
14. Higo K., Ugawa Y., Iwamoto M., and Korenaga T. Plant cis-acting regulatory DNA elements (PLACE) database: 1999. Nucleic Acids Res. 27 (1999) 297-300
15. Nicolas M., Noe V., Jensen K.B., and Ciudad C.J. Cloning and characterization of the 5′-flanking region of the human transcription factor Sp1 gene. J. Biol. Chem. 276 (2001) 22126-22132
16. Kovesdi I., Reichel R., and Nevins J.R. Identification of a cellular transcription factor involved in E1A trans-activation. Cell 45 (1986) 219-228
17. Brand A.H., Breeden L., Abraham J., Sternglanz R., and Nasmyth K. Characterization of a "silencer" in yeast: a DNA sequence with properties opposite to those of a transcriptional enhancer. Cell 41 (1985) 41-48
18. Ogbourne S., and Antalis T.M. Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes. Biochem. J. 331 (1998) 1-14
19. Moffat G.J., McLaren A.W., and Wolf C.R. Functional characterization of the transcription silencer element located within the human Pi class glutathione S-transferase promoter. J. Biol. Chem. 271 (1996) 20740-20747
20. Moffat G.J., McLaren A.W., and Wolf C.R. Transcriptional and post-transcriptional mechanisms can regulate cell-specific expression of the human Pi-class glutathione S-transferase gene. Biochem. J. 324 (1997) 91-95
21. Henderson C.J., McLaren A.W., Moffat G.J., Bacon E.J., and Wolf C.R. Pi-class glutathione S-transferase: regulation and function. Chem. Biol. Interact. 111-112 (1998) 69-82
22. Montminy M.R., and Bilezikjian L.M. Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene. Nature 328 (1987) 175-178
23. Hai T., Wolfgang C.D., Marsee D.K., Allen A.E., and Sivaprasad U. ATF3 and stress responses. Gene Expr. 7 (1999) 321-335
24. Chrivia J.C., Kwok R.P., Lamb N., Hagiwara M., Montminy M.R., and Goodman R.H. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365 (1993) 855-859
25. Zhang X., Odom D.T., Koo S.H., Conkright M.D., Canettieri G., Best J., Chen H., Jenner R., Herbolsheimer E., Jacobsen E., Kadam S., Ecker J.R., Emerson B., Hogenesch J.B., Unterman T., Young R.A., and Montminy M. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc. Natl. Acad. Sci. 102 (2005) 4459-4464
26. Screaton R.A., Conkright M.D., Katoh Y., Best J.L., Canettieri G., Jeffries S., Guzman E., Niessen S., Yates J.R., Takemori H., Okamoto M., and Montminy M. The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Cell 119 (2004) 61-74
27. Impey S., McCorkle S.R., Cha-Molstad H., Dwyer J.M., Yochum G.S., Boss J.M., McWeeney S., Dunn J.J., Mandel G., and Goodman R.H. Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell 119 (2004) 1041-1054
28. Shankar D.B., and Sakamoto K.M. The role of cyclic-AMP binding protein (CREB) in leukemia cell proliferation and acute leukemias. Leuk. Lymphoma 45 (2004) 265-270
29. Shankar D.B., Cheng J.C., and Sakamoto K.M. Role of cyclic AMP response element binding protein in human leukemias. Cancer 104 (2005) 1819-1824
30. Shankar D.B., Cheng J.C., and Sakamoto K.M. The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia. Cancer Cell 7 (2005) 351-362
31. Rutkowski D.T., and Kaufman R.J. All roads lead to ATF4. Dev. Cell 4 (2003) 442-444
32. Elefteriou F., Ahn J.D., Takeda S., Starbuck M., Yang X., Liu X., Kondo H., Richards W.G., Bannon T.W., Noda M., Clement K., Vaisse C., and Karsenty G. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature 434 (2005) 514-520
33. Yang X., Matsuda K., Bialek P., Jacquot S., Masuoka H.C., Schinke T., Li L., Brancorsini S., Sassone-Corsi P., Townes T.M., Hanauer A., and Karsenty G. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell 117 (2004) 387-398
34. Lassot I., Estrabaud E., Emiliani S., Benkirane M., Benarous R., and Margottin-Goguet F. p300 modulates ATF4 stability and transcriptional activity independently of its acetyltransferase domain. J. Biol. Chem. 280 (2005) 41537-41545
35. Sayer J.A., Otto E.A., OToole J.F., Nurnberg G., Kennedy M.A., Becker C., Hennies H.C., Helou J., Attanasio M., Fausett B.V., Utsch B., Khanna H., Liu Y., Drummond I., Kawakami I., Kusakabe T., Tsuda M., Ma L., Lee H., Larson R.G., Allen S.J., Wilkinson C.J., Nigg E.A., Shou C., Lillo C., Williams D.S., Hoppe B., Kemper M.J., Neuhaus T., Parisi M.A., Glass I.A., Petry M., Kispert A., Gloy J., Ganner A., Walz G., Zhu X., Goldman D., Nurnberg P., Swaroop A., Leroux M.R., and Hidebrandt F. The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat. Genet. 38 (2006) 674-681
36. Hai T., and Hartman M.G. The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis. Gene 273 (2001) 1-11
37. Liang G., and Hai T. Characterization of human activating transcription factor 4, a transcriptional activator that interacts with multiple domains of cAMP-responsive element-binding protein (CREB)-binding protein. J. Biol. Chem. 272 (1997) 24088-24095
38. Roy A.L., Malik S., Meisterernst M., and Roeder R.G. An alternative pathway for transcription initiation involving TFII-I. Nature 365 (1993) 355-359
39. Weis L., and Reinberg D. Transcription by RNA polymerase II: initiator-directed formation of transcription-competent complexes. FASEB J. 6 (1992) 3300-3309
40. Felinski E.A., Kim J., Lu J., and Quinn P.G. Recruitment of an RNA polymerase II complex is mediated by the constitutive activation domain in CREB, independently of CREB phosphorylation. Mol. Cell. Biol. 21 (2001) 1001-1010
41. Conkright M.D., Guzman E., Flechner L., Su A.I., Hogenesch J.B., and Montminy M. Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness. Mol. Cell 11 (2003) 1101-1108