UHPLC-MS/MS highly sensitive determination of aflatoxins, the aflatoxin metabolite M1 and ochratoxin A in baby food and milk

Food Chemistry

Volumn 126, Issue 2, 2011, Pages 737-744

  Beltrán, Eduardo ^a   Ibáñez, María ^a   Sancho, Juan Vicente ^a   Cortés, Miguel Ángel ^b   Yus, Vicent ^b   Hernández, Félix ^a  

^a UNIVERSITAT JAUME I   (Spain)

^b Public Health Laboratory of Valencia CSISP   (Spain)

Author keywords

Aflatoxins; Baby food; Immunoaffinity columns; MS MS; Ochratoxin A; UHPLC

Indexed keywords

BABY FOODS; IMMUNOAFFINITY COLUMNS; MS/MS; OCHRATOXIN A; UHPLC;

ACETONITRILE; AFLATOXINS; CHROMATOGRAPHY; MASS SPECTROMETRY; PATIENT REHABILITATION; RECOVERY; SOLVENT EXTRACTION;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

AFLATOXIN; AFLATOXIN B1; AFLATOXIN B2; AFLATOXIN G1; AFLATOXIN G2; AFLATOXIN M1; OCHRATOXIN;

ANTIBODY AFFINITY; ARTICLE; ARTIFICIAL MILK; BABY FOOD; CLINICAL ASSESSMENT; HUMAN; INFANT; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION PROCESS;

EID: 78650680249     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodchem.2010.11.056     Document Type: Article

References (29)

1. E. Beltrán, M. Ibáñez, J.V. Sancho, and F. Hernández Determination of mycotoxins in different food commodities by ultra-high-pressure liquid chromatography coupled to triple quadrupole mass spectrometry Rapid Communications in Mass Spectrometry 23 12 2009 1801 1809
2. D. Chan, S.J. MacDonald, V. Boughtflower, and P. Brereton Simultaneous determination of aflatoxins and ochratoxin a in food using a fully automated immunoaffinity column clean-up and liquid chromatography-fluorescence detection Journal of Chromatography A 1059 1-2 2004 13 16
3. Commission Regulation (EC) No. 1881/2006. (2006). Commission Directive 2006/1881/EC of 19 December 2006, setting maximum levels for certain contaminants in food stuffs. Official Journal of the European Communities, L364, 5-24.
4. B. Delmulle, S. De Saeger, A. Adams, N. De Kimpe, and C. Van Peteghem Development of a liquid chromatography/tandem mass spectrometry method for the simultaneous determination of 16 mycotoxins on cellulose filters and in fungal cultures Rapid Communications in Mass Spectrometry 20 5 2006 771 776
5. J.D. Di Mavungu, S. Monbaliu, M.-L. Scippo, G. Maghuin-Rogister, Y.-J. Schneider, and Y. Larondelle LC-MS/MS multi-analyte method for mycotoxin determination in food supplements Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 26 6 2009 885 895
6. A.G. Frenich, J.L.M. Vidal, R. Romero-González, and M.d. M. Aguilera-Luiz Simple and high-throughput method for the multimycotoxin analysis in cereals and related foods by ultra-high performance liquid chromatography/tandem mass spectrometry Food Chemistry 117 4 2009 705 712
7. Z. Fu, X. Huang, and S. Min Rapid determination of aflatoxins in corn and peanuts Journal of Chromatography A 1209 1-2 2008 271 274
8. R.J. Garcia-Villanova, C. Cordón, A.M. González Paramás, P. Aparicio, and M.E. Garcia Rosales Simultaneous immunoaffinity column cleanup and HPLC analysis of aflatoxins and ochratoxin A in Spanish bee pollen Journal of Agricultural and Food Chemistry 52 24 2004 7235 7239
9. R. Göbel, and K. Lusky Simultaneous determination of aflatoxins, ochratoxin A, and zearalenone in grains by new immunoaffinity column/liquid chromatography Journal of AOAC International 87 2 2004 411 416
10. D. Herebian, S. Zühlke, M. Lamshöft, and M. Spiteller Multi-mycotoxin analysis in complex biological matrices using LC-ESI/MS: Experimental study using triple stage quadrupole and LTQ-Orbitrap Journal of Separation Science 32 7 2009 939 948
11. F. Hernández, J.V. Sancho, and O.J. Pozo Critical review of the application of liquid chromatography/mass spectrometry to the determination of pesticide residues in biological samples Analytical and Bioanalytical Chemistry 382 4 2005 934 946
12. H.S. Hussein, and J.M. Brasel Toxicity, metabolism, and impact of mycotoxins on humans and animals Toxicology 167 2 2001 101 134
13. IARC, (1993). Some naturally occurring substances: Food items and constituents, heterocyclic aromatic amines and mycotoxins, monographs on the evaluation of carcinogenic risks to humans, vol. 56, International Agency for research on Cancer. Lyon.
14. J. Jaimez, C.A. Fente, B.I. Vazquez, C.M. Franco, A. Cepeda, and G. Mahuzier Application of the assay of aflatoxins by liquid chromatography with fluorescence detection in food analysis Journal of Chromatography A 882 1-2 2000 1 10
15. R. Krska, P. Schubert-Ullrich, A. Molinelli, M. Sulyok, S. MacDonald, and C. Crews Mycotoxin analysis: An update Food Additives and Contaminants 25 2 2008 152 163
16. V.M.T. Lattanzio, M. Solfrizzo, S. Powers, and A. Visconti Simultaneous determination of aflatoxins, ochratoxin A and Fusarium toxins in maize by liquid chromatography/tandem mass spectrometry after multitoxin immunoaffinity cleanup Rapid Communications in Mass Spectrometry 21 20 2007 3253 3261
17. O.J. Pozo, J.V. Sancho, M. Ibáñez, F. Hernández, and W.M.A. Niessen Confirmation of organic micropollutants detected in environmental samples by liquid chromatography tandem mass spectrometry: Achievements and pitfalls TrAC - Trends in Analytical Chemistry 25 10 2006 1030 1042
18. Y. Ren, Y. Zhang, S. Shao, Z. Cai, L. Feng, and H. Pan Simultaneous determination of multi-component mycotoxin contaminants in foods and feeds by ultra-performance liquid chromatography tandem mass spectrometry Journal of Chromatography A 1143 1-2 2007 48 64 (Pubitemid 46209099)
19. S. Sforza, C. Dall'Asta, and R. Marchelli Recent advances in mycotoxin determination in food and feed by hyphenated chromatographic techniques/mass spectrometry Mass Spectrometry Reviews 25 1 2006 54 76
20. G.S. Shephard Aflatoxin analysis at the beginning of the twenty-first century Analytical and Bioanalytical Chemistry 395 5 2009 1215 1224
21. E.A. Sizoo, and H.P. Van Egmond Analysis of duplicate 24-hour diet samples for aflatoxin B1, aflatoxin M1 and ochratoxin A Food additives and contaminants 22 2 2005 163 172
22. P. Songsermsakul, and E. Razzazi-Fazeli A review of recent trends in applications of liquid chromatography-mass spectrometry for determination of mycotoxins Journal of Liquid Chromatography and Related Technologies 31 11-12 2008 1641 1686
23. M.C. Spanjer, P.M. Rensen, and J.M. Scholten LC-MS/MS multi-method for mycotoxins after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs Food Additives and Contaminants 25 4 2008 472 489
24. M. Sulyok, F. Berthiller, R. Krska, and R. Schuhmacher Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize Rapid Communications in Mass Spectrometry 20 18 2006 2649 2659
25. M. Sulyok, R. Krska, and R. Schuhmacher Application of an LC-MS/MS based multi-mycotoxin method for the semi-quantitative determination of mycotoxins occurring in different types of food infected by moulds Food Chemistry 119 1 2010 408 416
26. N.W. Turner, S. Subrahmanyam, and S.A. Piletsky Analytical methods for determination of mycotoxins: A review Analytica Chimica Acta 632 2 2009 168 180
27. H.P. Van Egmond, R.C. Schothorst, and M.A. Jonker Regulations relating to mycotoxins in food: Perspectives in a global and European context Analytical and Bioanalytical Chemistry 389 1 2007 147 157
28. M. Ventura, D. Guillén,, I. Anaya, F. Broto-Puig, J.L. Lliberia, M. Agut, and L. Comellas Ultra-performance liquid chromatography/tandem mass spectrometry for the simultaneous analysis of aflatoxins B1, G1, B2, G2 and ochratoxin A in beer Rapid Communications in Mass Spectrometry 20 21 2006 3199 3204
29. P. Zöllner, and B. Mayer-Helm Trace mycotoxin analysis in complex biological and food matrices by liquid chromatography-atmospheric pressure ionisation mass spectrometry Journal of Chromatography A 1136 2 2006 123 169