Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate

Journal of Synchrotron Radiation

Volumn 18, Issue 1, 2011, Pages 62-65

  D'Muniz Pereira, Humberto ^a   Oliva, Glaucius ^a   Garratt, Richard Charles ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

purine nucleoside phosphorylase; ribose 1 phosphate; schistosomiasis

Indexed keywords

BINARY COMPLEXES; CONFORMATIONAL CHANGE; DE NOVO PATHWAY; DRUG DEVELOPMENT; GUANOSINES; HYDROGEN BONDING NETWORK; INOSINE; PURINE NUCLEOSIDE PHOSPHORYLASE; REVERSE REACTIONS; RIBOSE-1-PHOSPHATE; SALVAGE PATHWAY; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SELECTIVE INHIBITORS;

BINDING SITES; BIOCHEMISTRY; CRYSTAL STRUCTURE; ENZYMES; PHOSPHORYLATION; SYNTHESIS (CHEMICAL);

BIOMOLECULES;

ANTIMALARIAL AGENT; HYPOXANTHINE; PURINE NUCLEOSIDE PHOSPHORYLASE; RIBOSE 1 PHOSPHATE; RIBOSE 1-PHOSPHATE; RIBOSE PHOSPHATE;

ANIMAL; ARTICLE; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYMOLOGY; HYDROGEN BOND; METABOLISM; PROTEIN CONFORMATION; SCHISTOSOMA MANSONI; SYNTHESIS; X RAY DIFFRACTION;

ANIMALS; ANTIMALARIALS; CATALYTIC DOMAIN; CRYSTALLIZATION; HYDROGEN BONDING; HYPOXANTHINE; PROTEIN CONFORMATION; PURINE-NUCLEOSIDE PHOSPHORYLASE; RIBOSEMONOPHOSPHATES; SCHISTOSOMA MANSONI; X-RAY DIFFRACTION;

EID: 78650667861     PISSN: 09090495     EISSN: 16005775     Source Type: Journal    
DOI: 10.1107/S0909049510027718     Document Type: Conference Paper

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