Amyloid-β impairs, and ibuprofen restores, the cGMP pathway, synaptic expression of AMPA receptors and long-term potentiation in the hippocampus

Journal of Alzheimer's Disease

Volumn 22, Issue 3, 2010, Pages 795-809

  Monfort, Pilar ^a   Felipo, Vicente ^a  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

Alzheimer's disease; AMPA receptors; amyloid ; cGMP dependent protein kinase; GluR1; phosphorylation; synaptic plasticity

Indexed keywords

8 BROMO CYCLIC GMP; AMPA RECEPTOR; AMYLOID BETA PROTEIN; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; GLUTAMATE RECEPTOR 1; GUANYLATE CYCLASE; IBUPROFEN; NITRIC OXIDE; SERINE;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ENZYME ACTIVATION; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SYNAPTIC MEMBRANE; SYNAPTIC TRANSMISSION; TETANUS;

EID: 78650650912     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-101092     Document Type: Article

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