Mast cell fibroblastoid differentiation mediated by airway smooth muscle in asthma

Journal of Immunology

Volumn 185, Issue 10, 2010, Pages 6105-6114

  Kaur, Davinder ^a   Saunders, Ruth ^a   Hollins, Fay ^a   Woodman, Lucy ^a   Doe, Camille ^a   Siddiqui, Salman ^a   Bradding, Peter ^a   Brightling, Christopher ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMASE; SCLEROPROTEIN; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 5;

ADULT; AIRWAY SMOOTH MUSCLE; ARTICLE; ASTHMA; ATTENUATION; BRONCHUS MUCOSA; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST; HISTAMINE RELEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MAST CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE;

ASTHMA; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG; MAST CELLS; MUSCLE, SMOOTH;

EID: 78650650196     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000638     Document Type: Article

References (40)

1. Braman, S. S. 2006. The global burden of asthma. Chest 130 (1, Suppl) 4S-12S.
2. Chanez, P., S. E. Wenzel, G. P. Anderson, J. M. Anto, E. H. Bel, L. P. Boulet, C. E. Brightling, W. W. Busse, M. Castro, B. Dahlen, et al. 2007. Severe asthma in adults: what are the important questions? J. Allergy Clin. Immunol. 119:1337-1348.
3. Haldar, P., I. D. Pavord, D. E. Shaw, M. A. Berry, M. Thomas, C. E. Brightling, A. J. Wardlaw, and R. H. Green. 2008. Cluster analysis and clinical asthma phenotypes. Am. J. Respir. Crit. Care Med. 178:218-224.
4. Leckie, M. J., A. ten Brinke, J. Khan, Z. Z. Diamant, B. J. O'Connor, C. M. Walls, A. K. Mathur, H. C. Cowley, K. F. Chung, R. Djukanovic, et al. 2000. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 356:2144-2148.
5. Haldar, P., C. E. Brightling, B. Hargadon, S. Gupta, W. Monteiro, A. Sousa, R. P. Marshall, P. Bradding, R. H. Green, A. J. Wardlaw, and I. D. Pavord. 2009. Mepolizumab and exacerbations of eosinophilic refractory asthma. N. Engl. J. Med. 360:973-984.
6. Brightling, C. E., R. Ward, K. L. Goh, A. J. Wardlaw, and I. D. Pavord. 1999. Eosinophilic bronchitis is an important cause of chronic cough. Am. J. Respir. Crit. Care Med. 160:406-410.
7. Brightling, C. E., P. Bradding, F. A. Symon, S. T. Holgate, A. J. Wardlaw, and I. D. Pavord. 2002. Mast-cell infiltration of airway smooth muscle in asthma. N. Engl. J. Med. 346:1699-1705.
8. Siddiqui, S., V. Mistry, C. Doe, K. Roach, A. Morgan, A. Wardlaw, I. D. Pavord, P. Bradding, and C. E. Brightling. 2008. Airway hyperresponsiveness is dissociated from airway wall structural remodeling. J. Allergy Clin. Immunol. 122:335-341, 341, e1-e3.
9. Weller, C. L., S. J. Collington, J. K. Brown, H. R. Miller, A. Al-Kashi, P. Clark, P. J. Jose, A. Hartnell, and T. J. Williams. 2005. Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors. J. Exp. Med. 201:1961-1971.
10. Ochi, H., W. M. Hirani, Q. Yuan, D. S. Friend, K. F. Austen, and J. A. Boyce. 1999. T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro. J. Exp. Med. 190:267-280.
11. Abonia, J. P., J. Hallgren, T. Jones, T. Shi, Y. Xu, P. Koni, R. A. Flavell, J. A. Boyce, K. F. Austen, and M. F. Gurish. 2006. Alpha-4 integrins and VCAM-1, but not MAdCADM1, are essential for recruitment of mast cell progenitors to the inflamed lung. Blood 108:1588-1594.
12. Siddiqui, S., F. Hollins, S. Saha, and C. E. Brightling. 2007. Inflammatory cell microlocalisation and airway dysfunction: cause and effect? Eur. Respir. J. 30:1043-1056.
13. Brightling, C. E., A. J. Ammit, D. Kaur, J. L. Black, A. J. Wardlaw, J. M. Hughes, and P. Bradding. 2005. The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am. J. Respir. Crit. Care Med. 171:1103-1108.
14. Yang, W., D. Kaur, Y. Okayama, A. Ito, A. J. Wardlaw, C. E. Brightling, and P. Bradding. 2006. Human lung mast cells adhere to human airway smooth muscle, in part, via tumor suppressor in lung cancer-1. J. Immunol. 176:1238-1243.
15. Brightling, C. E., F. A. Symon, S. T. Holgate, A. J. Wardlaw, I. D. Pavord, and P. Bradding. 2003. Interleukin-4 and-13 expression is co-localized to mast cells within the airway smooth muscle in asthma. Clin. Exp. Allergy 33:1711-1716.
16. Saha, S. K., M. A. Berry, D. Parker, S. Siddiqui, A. Morgan, R. May, P. Monk, P. Bradding, A. J. Wardlaw, I. D. Pavord, and C. E. Brightling. 2008. Increased sputum and bronchial biopsy IL-13 expression in severe asthma. J. Allergy Clin. Immunol. 121:685-691.
17. Begueret, H., P. Berger, J. M. Vernejoux, L. Dubuisson, R. Marthan, and J. M. Tunon-de-Lara. 2007. Inflammation of bronchial smooth muscle in allergic asthma. Thorax 62:8-15.
18. Siddiqui, S., F. Hollins, and C. E. Brightling. 2008. What can we learn about airway smooth muscle from the company it keeps? Eur. Respir. J. 32:9-11.
19. Araujo, B. B., M. Dolhnikoff, L. F. Silva, J. Elliot, J. H. Lindeman, D. S. Ferreira, A. Mulder, H. A. Gomes, S. M. Fernezlian, A. James, and T. Mauad. 2008. Extracellular matrix components and regulators in the airway smooth muscle in asthma. Eur. Respir. J. 32:61-69.
20. Fouty, B., T. Moss, V. Solodushko, and M. Kraft. 2006. Dexamethasone can stimulate G1-S phase transition in human airway fibroblasts in asthma. Eur. Respir. J. 27:1160-1167.
21. Kaur, D., R. Saunders, P. Berger, S. Siddiqui, L. Woodman, A. Wardlaw, P. Bradding, and C. E. Brightling. 2006. Airway smooth muscle and mast cellderived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma. Am. J. Respir. Crit. Care Med. 174:1179-1188.
22. Furuno, T., A. A. Ito, Y. Koma, K. Wetabe, H. Yokozaki, J. Bienstock, M. Nakanishi, and Y. Kitamura. 2005. The spermatogenic Ig superfamily/synaptic cell adhesion molecule mast-cell adhesion molecule promotes interaction with nerves. J. Immunol. 174:6934-6942.
23. Hollins, F., D. Kaur, W. Yang, G. Cruse, R. Saunders, A. Sutcliffe, P. Berger, A. Ito, C. E. Brightling, and P. Bradding. 2008. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J. Immunol. 181:2772-2780.
24. Berger, P., P. O. Girodet, H. Begueret, O. Ousova, D. W. Perng, R. Marthan, A. F. Walls, and J. M. Tunon de Lara. 2003. Tryptase-stimulated human airway smooth muscle cells induce cytokine synthesis and mast cell chemotaxis. FASEB J. 17:2139-2141.
25. El-Shazly, A., P. Berger, P. O. Girodet, O. Ousova, M. Fayon, J. M. Vernejoux, R. Marthan, and J. M. Tunon-de-Lara. 2006. Fraktalkine produced by airway smooth muscle cells contributes to mast cell recruitment in asthma. J. Immunol. 176:1860-1868.
26. Swieter, M., M. M. Hamawy, R. P. Siraganian, and S. E. Mergenhagen. 1993. Mast cells and their microenvironment: the influence of fibronectin and fibroblasts on the functional repertoire of rat basophilic leukemia cells. J. Periodontol. 64 (5, Suppl) 492-496.
27. Küchler, J., A. Grützkau, B. M. Henz, and S. Krüger-Krasagakis. 2006. Morphological analysis of integrin-mediated adhesion of immature human mast cells to extracellular matrix proteins. Arch. Dermatol. Res. 298:153-161.
28. Kulka, M., and D. D. Metcalfe. 2006. TLR3 activation inhibits human mast cell attachment to fibronectin and vitronectin. Mol. Immunol. 43:1579-1586.
29. Dastych, J., and D. D. Metcalfe. 1994. Stem cell factor induces mast cell adhesion to fibronectin. J. Immunol. 152:213-219.
30. Dastych, J., J. Wyczółkowska, and D. D. Metcalfe. 2001. Characterization of alpha 5-integrin-dependent mast cell adhesion following Fc epsilon RI aggregation. Int. Arch. Allergy Immunol. 125:152-159.
31. Levi-Schaffer, F., K. F. Austen, J. P. Caulfield, A. Hein, W. F. Bloes, and R. L. Stevens. 1985. Fibroblasts maintain the phenotype and viability of the rat heparin-containing mast cell in vitro. J. Immunol. 135:3454-3462.
32. Rios, E. J., A. M. Piliponsky, C. Ra, J. Kalesnikoff, and S. J. Galli. 2008. Rabaptin-5 regulates receptor expression and functional activation in mast cells. Blood 112:4148-4157.
33. Lavens, S. E., K. Goldring, L. H. Thomas, and J. A. Warner. 1996. Effects of integrin clustering on human lung mast cells and basophils. Am. J. Respir. Cell Mol. Biol. 14:95-103.
34. Hamawy, M. M., C. Oliver, S. E. Mergenhagen, and R. P. Siraganian. 1992. Adherence of rat basophilic leukemia (RBL-2H3) cells to fibronectin-coated surfaces enhances secretion. J. Immunol. 149:615-621.
35. Woodman, L., S. Siddiqui, G. Cruse, A. Sutcliffe, R. Saunders, D. Kaur, P. Bradding, and C. E. Brightling. 2008. Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-β 1. J. Immunol. 181:5001-5007.
36. Johnson, P. R., J. K. Burgess, Q. Ge, M. Poniris, S. Boustany, S. M. Twigg, and J. L. Black. 2006. Connective tissue growth factor induces extracellular matrix in asthmatic airway smooth muscle. Am. J. Respir. Crit. Care Med. 173:32-41.
37. Moir, L. M., J. K. Burgess, and J. L. Black. 2008. Transforming growth factor beta 1 increases fibronectin deposition through integrin receptor alpha 5 beta 1 on human airway smooth muscle. J. Allergy Clin. Immunol. 121:1034-1039, e4.
38. Peng, Q., D. Lai, T. T. Nguyen, V. Chan, T. Matsuda, and S. J. Hirst. 2005. Multiple beta 1 integrins mediate enhancement of human airway smooth muscle cytokine secretion by fibronectin and type I collagen. J. Immunol. 174:2258-2264.
39. Chan, V., J. K. Burgess, J. C. Ratoff, B. J. O'Connor, A. Greenough, T. H. Lee, and S. J. Hirst. 2006. Extracellular matrix regulates enhanced eotaxin expression in asthmatic airway smooth muscle cells. Am. J. Respir. Crit. Care Med. 174:379-385.
40. Lam, V., J. Kalesnikoff, C. W. Lee, V. Hernandez-Hansen, B. S. Wilson, J. M. Oliver, and G. Krystal. 2003. IgE alone stimulates mast cell adhesion to fibronectin via pathways similar to those used by IgE + antigen but distinct from those used by Steel factor. Blood 102:1405-1413.