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Volumn 13, Issue 2, 2011, Pages 118-129

The potential role of glucagon-like peptide-1 or its analogues in enhancing glycaemic control in critically ill adult patients

Author keywords

Acute hyperglycaemia; Exenatide; GLP 1 analogues; Glycaemic control; Insulin intensive management; Intravenous insulin therapy; Type 2 diabetes mellitus

Indexed keywords

EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INCRETIN; INSULIN; METFORMIN; PIOGLITAZONE; SULFONYLUREA;

EID: 78650643032     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2010.01311.x     Document Type: Review
Times cited : (9)

References (108)
  • 1
    • 61849170118 scopus 로고    scopus 로고
    • Full accounting of diabetes and pre-diabetes in the U.S. population in 1988-1994 and 2005-2006.
    • Cowie CC, Rust KF, Ford ES et al. Full accounting of diabetes and pre-diabetes in the U.S. population in 1988-1994 and 2005-2006. Diabetes Care 2009; 32: 287-294.
    • (2009) Diabetes Care , vol.32 , pp. 287-294
    • Cowie, C.C.1    Rust, K.F.2    Ford, E.S.3
  • 2
    • 60349083976 scopus 로고    scopus 로고
    • Glycaemic dysregulation in nondiabetic patients after major lower limb prosthetic surgery.
    • Pili-Floury S, Mitifiot F, Penfornis A et al. Glycaemic dysregulation in nondiabetic patients after major lower limb prosthetic surgery. Diabetes Metab 2009; 35: 43-48.
    • (2009) Diabetes Metab , vol.35 , pp. 43-48
    • Pili-Floury, S.1    Mitifiot, F.2    Penfornis, A.3
  • 4
    • 57349171546 scopus 로고    scopus 로고
    • Prevalence of elevated hemoglobin A1c among patients admitted to the hospital without a diagnosis of diabetes.
    • Wexler DJ, Nathan DM, Grant RW, Regan S, Van Leuvan AL, Cagliero E. Prevalence of elevated hemoglobin A1c among patients admitted to the hospital without a diagnosis of diabetes. J Clin Endocrinol Metab 2008; 93: 4238-4244.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4238-4244
    • Wexler, D.J.1    Nathan, D.M.2    Grant, R.W.3    Regan, S.4    Van Leuvan, A.L.5    Cagliero, E.6
  • 5
    • 0842268332 scopus 로고    scopus 로고
    • Management of diabetes and hyperglycemia in hospitals.
    • Clement S, Braithwaite SS, Magee MF et al. Management of diabetes and hyperglycemia in hospitals. Diabetes Care 2004; 27: 553-591.
    • (2004) Diabetes Care , vol.27 , pp. 553-591
    • Clement, S.1    Braithwaite, S.S.2    Magee, M.F.3
  • 6
    • 0037849854 scopus 로고    scopus 로고
    • Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting.
    • Furnary AP, Gao G, Grunkemeier GL et al. Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg 2003; 125: 1007-1021.
    • (2003) J Thorac Cardiovasc Surg , vol.125 , pp. 1007-1021
    • Furnary, A.P.1    Gao, G.2    Grunkemeier, G.L.3
  • 7
    • 0842311554 scopus 로고    scopus 로고
    • Implementation of a safe and effective insulin infusion protocol in a medical intensive care unit.
    • Goldberg PA, Siegel MD, Sherwin RS et al. Implementation of a safe and effective insulin infusion protocol in a medical intensive care unit. Diabetes Care 2004; 27: 461-467.
    • (2004) Diabetes Care , vol.27 , pp. 461-467
    • Goldberg, P.A.1    Siegel, M.D.2    Sherwin, R.S.3
  • 8
    • 33847609717 scopus 로고    scopus 로고
    • Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit.
    • Hermans G, Wilmer A, Meersseman W et al. Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit. Am J Respir Crit Care Med 2007; 175: 480-489.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 480-489
    • Hermans, G.1    Wilmer, A.2    Meersseman, W.3
  • 9
    • 1842434301 scopus 로고    scopus 로고
    • Tight glycemic control in diabetic coronary artery bypass graft patients improves perioperative outcomes and decreases recurrent ischemic events.
    • Lazar HL, Chipkin SR, Fitzgerald CA, Bao Y, Cabral H, Apstein CS. Tight glycemic control in diabetic coronary artery bypass graft patients improves perioperative outcomes and decreases recurrent ischemic events. Circulation 2004; 109: 1497-1502.
    • (2004) Circulation , vol.109 , pp. 1497-1502
    • Lazar, H.L.1    Chipkin, S.R.2    Fitzgerald, C.A.3    Bao, Y.4    Cabral, H.5    Apstein, C.S.6
  • 10
    • 0030974812 scopus 로고    scopus 로고
    • Prospective randomised study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in Acute Myocardial Infarction) Study Group.
    • Malmberg K. Prospective randomised study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in Acute Myocardial Infarction) Study Group. BMJ 1997; 314: 1512-1515.
    • (1997) BMJ , vol.314 , pp. 1512-1515
    • Malmberg, K.1
  • 11
    • 20244384563 scopus 로고    scopus 로고
    • Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity.
    • Malmberg K, Ryden L, Wedel H et al. Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur Heart J 2005; 26: 650-661.
    • (2005) Eur Heart J , vol.26 , pp. 650-661
    • Malmberg, K.1    Ryden, L.2    Wedel, H.3
  • 13
    • 33845539898 scopus 로고    scopus 로고
    • Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm.
    • Van den Berghe G, Wilmer A, Milants I et al. Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes 2006; 55: 3151-3159.
    • (2006) Diabetes , vol.55 , pp. 3151-3159
    • Van den Berghe, G.1    Wilmer, A.2    Milants, I.3
  • 14
    • 0035829852 scopus 로고    scopus 로고
    • Intensive insulin therapy in the critically ill patients.
    • Van den Berghe G, Wouters P, Weekers F et al. Intensive insulin therapy in the critically ill patients. N Engl J Med 2001; 345: 1359-1367.
    • (2001) N Engl J Med , vol.345 , pp. 1359-1367
    • Van den Berghe, G.1    Wouters, P.2    Weekers, F.3
  • 15
    • 33845257074 scopus 로고    scopus 로고
    • Evaluation of nursing work effort and perceptions about blood glucose testing in tight glycemic control.
    • Aragon D. Evaluation of nursing work effort and perceptions about blood glucose testing in tight glycemic control. Am J Crit Care 2006; 15: 370-377.
    • (2006) Am J Crit Care , vol.15 , pp. 370-377
    • Aragon, D.1
  • 16
    • 4644241257 scopus 로고    scopus 로고
    • Intravenous insulin infusion therapy: indications, methods, and transition to subcutaneous insulin therapy.
    • Bode BW, Braithwaite SS, Steed RD, Davidson PC. Intravenous insulin infusion therapy: indications, methods, and transition to subcutaneous insulin therapy. Endocr Pract 2004; 10(Suppl. 2): 71-80.
    • (2004) Endocr Pract , vol.10 , Issue.SUPPL.. 2 , pp. 71-80
    • Bode, B.W.1    Braithwaite, S.S.2    Steed, R.D.3    Davidson, P.C.4
  • 17
    • 77649215841 scopus 로고    scopus 로고
    • Hypoglycemia and outcome in critically ill patients.
    • Egi M, Bellomo R, Stachowski E et al. Hypoglycemia and outcome in critically ill patients. Mayo Clin Proc 2010; 85: 217-224.
    • (2010) Mayo Clin Proc , vol.85 , pp. 217-224
    • Egi, M.1    Bellomo, R.2    Stachowski, E.3
  • 18
    • 38049096093 scopus 로고    scopus 로고
    • Intensive insulin therapy and pentastarch resuscitation in severe sepsis.
    • Brunkhorst FM, Engel C, Bloos F et al. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008; 358: 125-139.
    • (2008) N Engl J Med , vol.358 , pp. 125-139
    • Brunkhorst, F.M.1    Engel, C.2    Bloos, F.3
  • 19
    • 50449103607 scopus 로고    scopus 로고
    • Benefits and risks of tight glucose control in critically ill adults: a meta-analysis.
    • Wiener RS, Wiener DC, Larson RJ. Benefits and risks of tight glucose control in critically ill adults: a meta-analysis. JAMA 2008; 300: 933-944.
    • (2008) JAMA , vol.300 , pp. 933-944
    • Wiener, R.S.1    Wiener, D.C.2    Larson, R.J.3
  • 20
    • 65349096195 scopus 로고    scopus 로고
    • Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data.
    • Griesdale DE, de Souza RJ, van Dam RM et al. Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data. CMAJ 2009; 180: 821-827.
    • (2009) CMAJ , vol.180 , pp. 821-827
    • Griesdale, D.E.1    de Souza, R.J.2    van Dam, R.M.3
  • 21
    • 42149174900 scopus 로고    scopus 로고
    • Effect of perioperative insulin infusion on surgical morbidity and mortality: systematic review and meta-analysis of randomized trials.
    • Gandhi GY, Murad MH, Flynn DN et al. Effect of perioperative insulin infusion on surgical morbidity and mortality: systematic review and meta-analysis of randomized trials. Mayo Clin Proc 2008; 83: 418-430.
    • (2008) Mayo Clin Proc , vol.83 , pp. 418-430
    • Gandhi, G.Y.1    Murad, M.H.2    Flynn, D.N.3
  • 22
    • 67650470214 scopus 로고    scopus 로고
    • Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition: executive summary.
    • Martindale RG, McClave SA, Vanek VW et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition: executive summary. Crit Care Med 2009; 37: 1757-1761.
    • (2009) Crit Care Med , vol.37 , pp. 1757-1761
    • Martindale, R.G.1    McClave, S.A.2    Vanek, V.W.3
  • 23
    • 77951010226 scopus 로고    scopus 로고
    • Review article: glucose measurement in the operating room: more complicated than it seems.
    • Rice MJ, Pitkin AD, Coursin DB. Review article: glucose measurement in the operating room: more complicated than it seems. Anesth Analg 2010; 110: 1056-1065.
    • (2010) Anesth Analg , vol.110 , pp. 1056-1065
    • Rice, M.J.1    Pitkin, A.D.2    Coursin, D.B.3
  • 24
    • 1542509792 scopus 로고    scopus 로고
    • Intravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetes.
    • Meier JJ, Weyhe D, Michaely M et al. Intravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetes. Crit Care Med 2004; 32: 848-851.
    • (2004) Crit Care Med , vol.32 , pp. 848-851
    • Meier, J.J.1    Weyhe, D.2    Michaely, M.3
  • 25
    • 33748297182 scopus 로고    scopus 로고
    • Towards a feasible algorithm for tight glycaemic control in critically ill patients: a systematic review of the literature.
    • Meijering S, Corstjens AM, Tulleken JE, Meertens JH, Zijlstra JG, Ligtenberg JJ. Towards a feasible algorithm for tight glycaemic control in critically ill patients: a systematic review of the literature. Crit Care 2006; 10: R19.
    • (2006) Crit Care , vol.10
    • Meijering, S.1    Corstjens, A.M.2    Tulleken, J.E.3    Meertens, J.H.4    Zijlstra, J.G.5    Ligtenberg, J.J.6
  • 26
    • 0025863562 scopus 로고
    • Metabolic control in diabetic subjects following myocardial infarction: difficulties in improving blood glucose levels by intravenous insulin infusion.
    • Davies RR, Newton RW, McNeill GP, Fisher BM, Kesson CM, Pearson D. Metabolic control in diabetic subjects following myocardial infarction: difficulties in improving blood glucose levels by intravenous insulin infusion. Scott Med J 1991; 36: 74-76.
    • (1991) Scott Med J , vol.36 , pp. 74-76
    • Davies, R.R.1    Newton, R.W.2    McNeill, G.P.3    Fisher, B.M.4    Kesson, C.M.5    Pearson, D.6
  • 27
    • 0026712855 scopus 로고
    • An algorithm for tight glycaemic control in diabetic infarct survivors.
    • Hendra TJ, Yudkin JS. An algorithm for tight glycaemic control in diabetic infarct survivors. Diabetes Res Clin Pract 1992; 16: 213-220.
    • (1992) Diabetes Res Clin Pract , vol.16 , pp. 213-220
    • Hendra, T.J.1    Yudkin, J.S.2
  • 28
    • 0037322441 scopus 로고    scopus 로고
    • Validation of a glucose-insulin-potassium infusion algorithm in hospitalized diabetic patients.
    • Bonnier M, Lonnroth P, Gudbjornsdottir S, Attvall S, Jansson PA. Validation of a glucose-insulin-potassium infusion algorithm in hospitalized diabetic patients. J Intern Med 2003; 253: 189-193.
    • (2003) J Intern Med , vol.253 , pp. 189-193
    • Bonnier, M.1    Lonnroth, P.2    Gudbjornsdottir, S.3    Attvall, S.4    Jansson, P.A.5
  • 29
    • 0032894044 scopus 로고    scopus 로고
    • Glucose potassium insulin infusions in the treatment of acute stroke patients with mild to moderate hyperglycemia: the Glucose Insulin in Stroke Trial (GIST).
    • Scott JF, Robinson GM, French JM, O'Connell JE, Alberti KG, Gray CS. Glucose potassium insulin infusions in the treatment of acute stroke patients with mild to moderate hyperglycemia: the Glucose Insulin in Stroke Trial (GIST). Stroke 1999; 30: 793-799.
    • (1999) Stroke , vol.30 , pp. 793-799
    • Scott, J.F.1    Robinson, G.M.2    French, J.M.3    O'Connell, J.E.4    Alberti, K.G.5    Gray, C.S.6
  • 30
    • 2442618379 scopus 로고    scopus 로고
    • Standardization of intravenous insulin therapy improves the efficiency and safety of blood glucose control in critically ill adults.
    • Kanji S, Singh A, Tierney M, Meggison H, McIntyre L, Hebert PC. Standardization of intravenous insulin therapy improves the efficiency and safety of blood glucose control in critically ill adults. Intensive Care Med 2004; 30: 804-810.
    • (2004) Intensive Care Med , vol.30 , pp. 804-810
    • Kanji, S.1    Singh, A.2    Tierney, M.3    Meggison, H.4    McIntyre, L.5    Hebert, P.C.6
  • 31
    • 35948960340 scopus 로고    scopus 로고
    • Comparison of a nurse initiated insulin infusion protocol for intensive insulin therapy between adult surgical trauma, medical and coronary care intensive care patients.
    • Barth MM, Oyen LJ, Warfield KT et al. Comparison of a nurse initiated insulin infusion protocol for intensive insulin therapy between adult surgical trauma, medical and coronary care intensive care patients. BMC Emerg Med 2007; 7: 14.
    • (2007) BMC Emerg Med , vol.7 , pp. 14
    • Barth, M.M.1    Oyen, L.J.2    Warfield, K.T.3
  • 32
    • 33746583335 scopus 로고    scopus 로고
    • Clinical effects of hyperglycemia in the cardiac surgery population: the Portland Diabetic Project.
    • Furnary AP, Wu Y. Clinical effects of hyperglycemia in the cardiac surgery population: the Portland Diabetic Project. Endocr Pract 2006; 12(Suppl. 3): 22-26.
    • (2006) Endocr Pract , vol.12 , Issue.SUPPL.. 3 , pp. 22-26
    • Furnary, A.P.1    Wu, Y.2
  • 33
    • 76649100731 scopus 로고    scopus 로고
    • Efficacy and safety of an insulin infusion protocol during and after cardiac surgery.
    • Studer C, Sankou W, Penfornis A et al. Efficacy and safety of an insulin infusion protocol during and after cardiac surgery. Diabetes Metab 2010; 36: 71-78.
    • (2010) Diabetes Metab , vol.36 , pp. 71-78
    • Studer, C.1    Sankou, W.2    Penfornis, A.3
  • 34
    • 34147185294 scopus 로고    scopus 로고
    • Intensive insulin therapy in critical care: a review of 12 protocols.
    • Wilson M, Weinreb J, Hoo GW. Intensive insulin therapy in critical care: a review of 12 protocols. Diabetes Care 2007; 30: 1005-1011.
    • (2007) Diabetes Care , vol.30 , pp. 1005-1011
    • Wilson, M.1    Weinreb, J.2    Hoo, G.W.3
  • 35
    • 6344255242 scopus 로고    scopus 로고
    • Insulin therapy for critically ill hospitalized patients: a meta-analysis of randomized controlled trials.
    • Pittas AG, Siegel RD, Lau J. Insulin therapy for critically ill hospitalized patients: a meta-analysis of randomized controlled trials. Arch Intern Med 2004; 164: 2005-2011.
    • (2004) Arch Intern Med , vol.164 , pp. 2005-2011
    • Pittas, A.G.1    Siegel, R.D.2    Lau, J.3
  • 36
    • 0034603545 scopus 로고    scopus 로고
    • Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview.
    • Capes SE, Hunt D, Malmberg K, Gerstein HC. Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet 2000; 355: 773-778.
    • (2000) Lancet , vol.355 , pp. 773-778
    • Capes, S.E.1    Hunt, D.2    Malmberg, K.3    Gerstein, H.C.4
  • 37
    • 20544451806 scopus 로고    scopus 로고
    • Admission glucose and mortality in elderly patients hospitalized with acute myocardial infarction: implications for patients with and without recognized diabetes.
    • Kosiborod M, Rathore SS, Inzucchi SE et al. Admission glucose and mortality in elderly patients hospitalized with acute myocardial infarction: implications for patients with and without recognized diabetes. Circulation 2005; 111: 3078-3086.
    • (2005) Circulation , vol.111 , pp. 3078-3086
    • Kosiborod, M.1    Rathore, S.S.2    Inzucchi, S.E.3
  • 38
    • 0345374590 scopus 로고    scopus 로고
    • Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients.
    • Krinsley JS. Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients. Mayo Clin Proc 2003; 78: 1471-1478.
    • (2003) Mayo Clin Proc , vol.78 , pp. 1471-1478
    • Krinsley, J.S.1
  • 39
    • 29144479953 scopus 로고    scopus 로고
    • Impact of admission hyperglycemia on hospital mortality in various intensive care unit populations.
    • Whitcomb BW, Pradhan EK, Pittas AG, Roghmann MC, Perencevich EN. Impact of admission hyperglycemia on hospital mortality in various intensive care unit populations. Crit Care Med 2005; 33: 2772-2777.
    • (2005) Crit Care Med , vol.33 , pp. 2772-2777
    • Whitcomb, B.W.1    Pradhan, E.K.2    Pittas, A.G.3    Roghmann, M.C.4    Perencevich, E.N.5
  • 40
    • 33746366222 scopus 로고    scopus 로고
    • The hyperglycemia: Intensive Insulin Infusion in Infarction (HI-5) study: a randomized controlled trial of insulin infusion therapy for myocardial infarction.
    • Cheung NW, Wong VW, McLean M. The hyperglycemia: Intensive Insulin Infusion in Infarction (HI-5) study: a randomized controlled trial of insulin infusion therapy for myocardial infarction. Diabetes Care 2006; 29: 765-770.
    • (2006) Diabetes Care , vol.29 , pp. 765-770
    • Cheung, N.W.1    Wong, V.W.2    McLean, M.3
  • 41
    • 33947546482 scopus 로고    scopus 로고
    • Glycemic control, diabetic status, and mortality in a heterogeneous population of critically ill patients before and during the era of intensive glycemic management: six and one-half years experience at a university-affiliated community hospital.
    • Krinsley JS. Glycemic control, diabetic status, and mortality in a heterogeneous population of critically ill patients before and during the era of intensive glycemic management: six and one-half years experience at a university-affiliated community hospital. Semin Thorac Cardiovasc Surg 2006; 18: 317-325.
    • (2006) Semin Thorac Cardiovasc Surg , vol.18 , pp. 317-325
    • Krinsley, J.S.1
  • 42
    • 28544447013 scopus 로고    scopus 로고
    • Influence of individual characteristics on outcome of glycemic control in intensive care unit patients with or without diabetes mellitus.
    • Rady MY, Johnson DJ, Patel BM, Larson JS, Helmers RA. Influence of individual characteristics on outcome of glycemic control in intensive care unit patients with or without diabetes mellitus. Mayo Clin Proc 2005; 80: 1558-1567.
    • (2005) Mayo Clin Proc , vol.80 , pp. 1558-1567
    • Rady, M.Y.1    Johnson, D.J.2    Patel, B.M.3    Larson, J.S.4    Helmers, R.A.5
  • 43
    • 63249128249 scopus 로고    scopus 로고
    • Intensive versus conventional glucose control in critically ill patients.
    • Finfer S, Chittock DR, Su SY et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med 2009; 360: 1283-1297.
    • (2009) N Engl J Med , vol.360 , pp. 1283-1297
    • Finfer, S.1    Chittock, D.R.2    Su, S.Y.3
  • 44
    • 55349134410 scopus 로고    scopus 로고
    • Glycemic variability: a strong independent predictor of mortality in critically ill patients.
    • Krinsley JS. Glycemic variability: a strong independent predictor of mortality in critically ill patients. Crit Care Med 2008; 36: 3008-3013.
    • (2008) Crit Care Med , vol.36 , pp. 3008-3013
    • Krinsley, J.S.1
  • 45
    • 33746621650 scopus 로고    scopus 로고
    • Variability of blood glucose concentration and short-term mortality in critically ill patients.
    • Egi M, Bellomo R, Stachowski E, French CJ, Hart GK. Variability of blood glucose concentration and short-term mortality in critically ill patients. Anesthesiology 2006; 105: 244-252.
    • (2006) Anesthesiology , vol.105 , pp. 244-252
    • Egi, M.1    Bellomo, R.2    Stachowski, E.3    French, C.J.4    Hart, G.K.5
  • 47
    • 67650689607 scopus 로고    scopus 로고
    • The impact of early hypoglycemia and blood glucose variability on outcome in critical illness.
    • Bagshaw RJ, Bellomo R, Jacka MJ et al. The impact of early hypoglycemia and blood glucose variability on outcome in critical illness. Crit Care 2009; 13: R91.
    • (2009) Crit Care , vol.13
    • Bagshaw, R.J.1    Bellomo, R.2    Jacka, M.J.3
  • 48
    • 55349103078 scopus 로고    scopus 로고
    • The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability.
    • Waeschle RM, Moerer O, Hilgers R, Herrmann P, Neumann P, Quintel M. The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability. Crit Care 2008; 12: R129.
    • (2008) Crit Care , vol.12
    • Waeschle, R.M.1    Moerer, O.2    Hilgers, R.3    Herrmann, P.4    Neumann, P.5    Quintel, M.6
  • 49
    • 49949108319 scopus 로고    scopus 로고
    • Glucose variability and mortality in patients with sepsis.
    • Ali NA, O'Brien JM Jr, Dungan K et al. Glucose variability and mortality in patients with sepsis. Crit Care Med 2008; 36: 2316-2321.
    • (2008) Crit Care Med , vol.36 , pp. 2316-2321
    • Ali, N.A.1    O'Brien Jr, J.M.2    Dungan, K.3
  • 50
    • 0035141399 scopus 로고    scopus 로고
    • A prospective survey of nutritional support practices in intensive care unit patients: What is prescribed? What is delivered?
    • De Jonghe B, Appere-De-Vechi C, Fournier M et al. A prospective survey of nutritional support practices in intensive care unit patients: What is prescribed? What is delivered? Crit Care Med 2001; 29: 8-12.
    • (2001) Crit Care Med , vol.29 , pp. 8-12
    • De Jonghe, B.1    Appere-De-Vechi, C.2    Fournier, M.3
  • 51
    • 0037243881 scopus 로고    scopus 로고
    • Nutrition support in the critical care setting: current practice in Canadian ICUs-opportunities for improvement?
    • Heyland DK, Schroter-Noppe D, Drover JW et al. Nutrition support in the critical care setting: current practice in Canadian ICUs-opportunities for improvement? JPEN J Parenter Enteral Nutr 2003; 27: 74-83.
    • (2003) JPEN J Parenter Enteral Nutr , vol.27 , pp. 74-83
    • Heyland, D.K.1    Schroter-Noppe, D.2    Drover, J.W.3
  • 52
    • 0029019079 scopus 로고
    • Nutritional support in intensive care units in England and Wales: a survey.
    • Hill SA, Nielsen MS, Lennard-Jones JE. Nutritional support in intensive care units in England and Wales: a survey. Eur J Clin Nutr 1995; 49: 371-378.
    • (1995) Eur J Clin Nutr , vol.49 , pp. 371-378
    • Hill, S.A.1    Nielsen, M.S.2    Lennard-Jones, J.E.3
  • 53
    • 0031897781 scopus 로고    scopus 로고
    • Grains or veins: Is enteral nutrition really better than parenteral nutrition? A look at the evidence.
    • Lipman TO. Grains or veins: Is enteral nutrition really better than parenteral nutrition? A look at the evidence. JPEN J Parenter Enteral Nutr 1998; 22: 167-182.
    • (1998) JPEN J Parenter Enteral Nutr , vol.22 , pp. 167-182
    • Lipman, T.O.1
  • 54
    • 0026788450 scopus 로고
    • Artificial nutrition support in hospitals in the United Kingdom-1991: second national survey.
    • Payne-James JJ, De Gara CJ, Grimble GK et al. Artificial nutrition support in hospitals in the United Kingdom-1991: second national survey. Clin Nutr 1992; 11: 187-192.
    • (1992) Clin Nutr , vol.11 , pp. 187-192
    • Payne-James, J.J.1    De Gara, C.J.2    Grimble, G.K.3
  • 55
    • 0033028752 scopus 로고    scopus 로고
    • Management of nutrition in European intensive care units: results of a questionnaire. Working Group on Metabolism and Nutrition of the European Society of Intensive Care Medicine.
    • Preiser JC, Berre J, Carpentier Y et al. Management of nutrition in European intensive care units: results of a questionnaire. Working Group on Metabolism and Nutrition of the European Society of Intensive Care Medicine. Intensive Care Med 1999; 25: 95-101.
    • (1999) Intensive Care Med , vol.25 , pp. 95-101
    • Preiser, J.C.1    Berre, J.2    Carpentier, Y.3
  • 56
    • 4944259806 scopus 로고    scopus 로고
    • Does enteral nutrition compared to parenteral nutrition result in better outcomes in critically ill adult patients? A systematic review of the literature.
    • Gramlich L, Kichian K, Pinilla J, Rodych NJ, Dhaliwal R, Heyland DK. Does enteral nutrition compared to parenteral nutrition result in better outcomes in critically ill adult patients? A systematic review of the literature. Nutrition 2004; 20: 843-848.
    • (2004) Nutrition , vol.20 , pp. 843-848
    • Gramlich, L.1    Kichian, K.2    Pinilla, J.3    Rodych, N.J.4    Dhaliwal, R.5    Heyland, D.K.6
  • 57
    • 33846948991 scopus 로고    scopus 로고
    • Enteral nutrition versus glucose-based or lipid-based parenteral nutrition and tight glycaemic control in critically ill patients.
    • Dan A, Jacques TC, O'Leary MJ. Enteral nutrition versus glucose-based or lipid-based parenteral nutrition and tight glycaemic control in critically ill patients. Crit Care Resusc 2006; 8: 283-288.
    • (2006) Crit Care Resusc , vol.8 , pp. 283-288
    • Dan, A.1    Jacques, T.C.2    O'Leary, M.J.3
  • 58
    • 0037326620 scopus 로고    scopus 로고
    • Outcome benefit of intensive insulin therapy in the critically ill: insulin dose versus glycemic control.
    • Van den Berghe G, Wouters PJ, Bouillon R et al. Outcome benefit of intensive insulin therapy in the critically ill: insulin dose versus glycemic control. Crit Care Med 2003; 31: 359-366.
    • (2003) Crit Care Med , vol.31 , pp. 359-366
    • Van den Berghe, G.1    Wouters, P.J.2    Bouillon, R.3
  • 59
    • 29744458366 scopus 로고    scopus 로고
    • Predisposing factors for hypoglycemia in the intensive care unit.
    • Vriesendorp TM, van Santen S, DeVries JH et al. Predisposing factors for hypoglycemia in the intensive care unit. Crit Care Med 2006; 34: 96-101.
    • (2006) Crit Care Med , vol.34 , pp. 96-101
    • Vriesendorp, T.M.1    van Santen, S.2    DeVries, J.H.3
  • 60
    • 77955508222 scopus 로고    scopus 로고
    • What makes tight glycemic control tight? The impact of variability and nutrition in two clinical studies.
    • Suhaimi F, Le Compte A, Preiser JC et al. What makes tight glycemic control tight? The impact of variability and nutrition in two clinical studies. J Diabetes Sci Technol 2010; 4: 284-298.
    • (2010) J Diabetes Sci Technol , vol.4 , pp. 284-298
    • Suhaimi, F.1    Le Compte, A.2    Preiser, J.C.3
  • 61
    • 77949499927 scopus 로고    scopus 로고
    • Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis.
    • Marik PE, Preiser JC. Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis. Chest 2010; 137: 544-551.
    • (2010) Chest , vol.137 , pp. 544-551
    • Marik, P.E.1    Preiser, J.C.2
  • 64
    • 0036150058 scopus 로고    scopus 로고
    • Insulin subcutaneous application vs. continuous infusion for postoperative blood glucose control in patients with non-insulin-dependent diabetes mellitus.
    • Gonzalez-Michaca L, Ahumada M, Ponce-de-Leon S. Insulin subcutaneous application vs. continuous infusion for postoperative blood glucose control in patients with non-insulin-dependent diabetes mellitus. Arch Med Res 2002; 33: 48-52.
    • (2002) Arch Med Res , vol.33 , pp. 48-52
    • Gonzalez-Michaca, L.1    Ahumada, M.2    Ponce-de-Leon, S.3
  • 65
    • 0028267595 scopus 로고
    • Perioperative diabetes regulation with the help of a standard protocol.
    • Jaspers CA, Elte JW, Olthof G. Perioperative diabetes regulation with the help of a standard protocol. Neth J Med 1994; 44: 122-130.
    • (1994) Neth J Med , vol.44 , pp. 122-130
    • Jaspers, C.A.1    Elte, J.W.2    Olthof, G.3
  • 66
    • 0029069020 scopus 로고
    • Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year.
    • Malmberg K, Ryden L, Efendic S et al. Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. J Am Coll Cardiol 1995; 26: 57-65.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 57-65
    • Malmberg, K.1    Ryden, L.2    Efendic, S.3
  • 67
    • 0028146874 scopus 로고
    • Feasibility of insulin-glucose infusion in diabetic patients with acute myocardial infarction. A report from the multicenter trial: DIGAMI.
    • Malmberg KA, Efendic S, Ryden LE. Feasibility of insulin-glucose infusion in diabetic patients with acute myocardial infarction. A report from the multicenter trial: DIGAMI. Diabetes Care 1994; 17: 1007-1014.
    • (1994) Diabetes Care , vol.17 , pp. 1007-1014
    • Malmberg, K.A.1    Efendic, S.2    Ryden, L.E.3
  • 68
    • 0036164218 scopus 로고    scopus 로고
    • Description and evaluation of a glycemic management protocol for patients with diabetes undergoing heart surgery.
    • Markovitz LJ, Wiechmann RJ, Harris N et al. Description and evaluation of a glycemic management protocol for patients with diabetes undergoing heart surgery. Endocr Pract 2002; 8: 10-18.
    • (2002) Endocr Pract , vol.8 , pp. 10-18
    • Markovitz, L.J.1    Wiechmann, R.J.2    Harris, N.3
  • 69
    • 0023921220 scopus 로고
    • Perioperative management of diabetic subjects. Subcutaneous versus intravenous insulin administration during glucose-potassium infusion.
    • Pezzarossa A, Taddei F, Cimicchi MC et al. Perioperative management of diabetic subjects. Subcutaneous versus intravenous insulin administration during glucose-potassium infusion. Diabetes Care 1988; 11: 52-58.
    • (1988) Diabetes Care , vol.11 , pp. 52-58
    • Pezzarossa, A.1    Taddei, F.2    Cimicchi, M.C.3
  • 70
    • 0036790707 scopus 로고    scopus 로고
    • Intensive insulin treatment reduces transient ischaemic episodes during acute coronary events in diabetic patients.
    • Stefanidis A, Melidonis A, Tournis S et al. Intensive insulin treatment reduces transient ischaemic episodes during acute coronary events in diabetic patients. Acta Cardiol 2002; 57: 357-364.
    • (2002) Acta Cardiol , vol.57 , pp. 357-364
    • Stefanidis, A.1    Melidonis, A.2    Tournis, S.3
  • 71
    • 0023589361 scopus 로고
    • Postoperative management of diabetes mellitus: steady-state glucose control with bedside algorithm for insulin adjustment.
    • Watts NB, Gebhart SS, Clark RV, Phillips LS. Postoperative management of diabetes mellitus: steady-state glucose control with bedside algorithm for insulin adjustment. Diabetes Care 1987; 10: 722-728.
    • (1987) Diabetes Care , vol.10 , pp. 722-728
    • Watts, N.B.1    Gebhart, S.S.2    Clark, R.V.3    Phillips, L.S.4
  • 72
    • 72249083789 scopus 로고    scopus 로고
    • A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study.
    • Preiser JC, Devos P, Ruiz-Santana S et al. A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study. Intensive Care Med 2009; 35: 1738-1748.
    • (2009) Intensive Care Med , vol.35 , pp. 1738-1748
    • Preiser, J.C.1    Devos, P.2    Ruiz-Santana, S.3
  • 73
    • 34447506735 scopus 로고    scopus 로고
    • Severe hypoglycemia in critically ill patients: risk factors and outcomes.
    • Krinsley JS, Grover A. Severe hypoglycemia in critically ill patients: risk factors and outcomes. Crit Care Med 2007; 35: 2262-2267.
    • (2007) Crit Care Med , vol.35 , pp. 2262-2267
    • Krinsley, J.S.1    Grover, A.2
  • 74
    • 64749086505 scopus 로고    scopus 로고
    • Relationship between spontaneous and iatrogenic hypoglycemia and mortality in patients hospitalized with acute myocardial infarction.
    • Kosiborod M, Inzucchi SE, Goyal A et al. Relationship between spontaneous and iatrogenic hypoglycemia and mortality in patients hospitalized with acute myocardial infarction. JAMA 2009; 301: 1556-1564.
    • (2009) JAMA , vol.301 , pp. 1556-1564
    • Kosiborod, M.1    Inzucchi, S.E.2    Goyal, A.3
  • 75
    • 59749098319 scopus 로고    scopus 로고
    • Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study.
    • Vlasselaers D, Milants I, Desmet L et al. Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study. Lancet 2009; 373: 547-556.
    • (2009) Lancet , vol.373 , pp. 547-556
    • Vlasselaers, D.1    Milants, I.2    Desmet, L.3
  • 76
    • 28544446712 scopus 로고    scopus 로고
    • Glycemic control in the intensive care unit: why we should wait for NICE-SUGAR.
    • Bellomo R, Egi M. Glycemic control in the intensive care unit: why we should wait for NICE-SUGAR. Mayo Clin Proc 2005; 80: 1546-1548.
    • (2005) Mayo Clin Proc , vol.80 , pp. 1546-1548
    • Bellomo, R.1    Egi, M.2
  • 77
    • 66549097705 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control.
    • Moghissi ES, Korytkowski MT, DiNardo M et al. American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care 2009; 32: 1119-1131.
    • (2009) Diabetes Care , vol.32 , pp. 1119-1131
    • Moghissi, E.S.1    Korytkowski, M.T.2    DiNardo, M.3
  • 78
    • 37549020378 scopus 로고    scopus 로고
    • Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.
    • Dellinger RP, Levy MM, Carlet JM et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008; 36: 296-327.
    • (2008) Crit Care Med , vol.36 , pp. 296-327
    • Dellinger, R.P.1    Levy, M.M.2    Carlet, J.M.3
  • 79
    • 57649234120 scopus 로고    scopus 로고
    • The incretin system and its role in type 2 diabetes mellitus.
    • Holst JJ, Vilsboll T, Deacon CF. The incretin system and its role in type 2 diabetes mellitus. Mol Cell Endocrinol 2009; 297: 127-136.
    • (2009) Mol Cell Endocrinol , vol.297 , pp. 127-136
    • Holst, J.J.1    Vilsboll, T.2    Deacon, C.F.3
  • 80
    • 67049155251 scopus 로고    scopus 로고
    • Unraveling the science of incretin biology.
    • Nauck MA. Unraveling the science of incretin biology. Am J Med 2009; 122: S3-S10.
    • (2009) Am J Med , vol.122
    • Nauck, M.A.1
  • 81
    • 0036828227 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats.
    • Farilla L, Hui H, Bertolotto C et al. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 2002; 143: 4397-4408.
    • (2002) Endocrinology , vol.143 , pp. 4397-4408
    • Farilla, L.1    Hui, H.2    Bertolotto, C.3
  • 82
    • 33646394592 scopus 로고    scopus 로고
    • Effects of intravenous glucagon-like peptide-1 on gastric emptying and intragastric distribution in healthy subjects: relationships with postprandial glycemic and insulinemic responses.
    • Little TJ, Pilichiewicz AN, Russo A et al. Effects of intravenous glucagon-like peptide-1 on gastric emptying and intragastric distribution in healthy subjects: relationships with postprandial glycemic and insulinemic responses. J Clin Endocrinol Metab 2006; 91: 1916-1923.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1916-1923
    • Little, T.J.1    Pilichiewicz, A.N.2    Russo, A.3
  • 83
    • 63849248275 scopus 로고    scopus 로고
    • Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety.
    • Williams DL, Baskin DG, Schwartz MW. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology 2009; 150: 1680-1687.
    • (2009) Endocrinology , vol.150 , pp. 1680-1687
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 84
    • 0029907680 scopus 로고    scopus 로고
    • Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM.
    • Nauck MA, Wollschlager D, Werner J et al. Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM. Diabetologia 1996; 39: 1546-1553.
    • (1996) Diabetologia , vol.39 , pp. 1546-1553
    • Nauck, M.A.1    Wollschlager, D.2    Werner, J.3
  • 85
    • 0035514550 scopus 로고    scopus 로고
    • Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes.
    • Meneilly GS, McIntosh CH, Pederson RA et al. Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes. Diabetes Care 2001; 24: 1951-1956.
    • (2001) Diabetes Care , vol.24 , pp. 1951-1956
    • Meneilly, G.S.1    McIntosh, C.H.2    Pederson, R.A.3
  • 86
    • 0031724691 scopus 로고    scopus 로고
    • Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure.
    • Nauck MA, Sauerwald A, Ritzel R, Holst JJ, Schmiegel W. Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure. Diabetes Care 1998; 21: 1925-1931.
    • (1998) Diabetes Care , vol.21 , pp. 1925-1931
    • Nauck, M.A.1    Sauerwald, A.2    Ritzel, R.3    Holst, J.J.4    Schmiegel, W.5
  • 87
    • 0035432607 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 infusion must be maintained for 24 h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment.
    • Larsen J, Hylleberg B, Ng K, Damsbo P. Glucagon-like peptide-1 infusion must be maintained for 24 h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment. Diabetes Care 2001; 24: 1416-1421.
    • (2001) Diabetes Care , vol.24 , pp. 1416-1421
    • Larsen, J.1    Hylleberg, B.2    Ng, K.3    Damsbo, P.4
  • 88
    • 0034827252 scopus 로고    scopus 로고
    • Additive glucose-lowering effects of glucagon-like peptide-1 and metformin in type 2 diabetes.
    • Zander M, Taskiran M, Toft-Nielsen MB, Madsbad S, Holst JJ. Additive glucose-lowering effects of glucagon-like peptide-1 and metformin in type 2 diabetes. Diabetes Care 2001; 24: 720-725.
    • (2001) Diabetes Care , vol.24 , pp. 720-725
    • Zander, M.1    Taskiran, M.2    Toft-Nielsen, M.B.3    Madsbad, S.4    Holst, J.J.5
  • 89
    • 3342971029 scopus 로고    scopus 로고
    • Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes.
    • Zander M, Christiansen A, Madsbad S, Holst JJ. Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes. Diabetes Care 2004; 27: 1910-1914.
    • (2004) Diabetes Care , vol.27 , pp. 1910-1914
    • Zander, M.1    Christiansen, A.2    Madsbad, S.3    Holst, J.J.4
  • 90
    • 0032976939 scopus 로고    scopus 로고
    • Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients.
    • Toft-Nielsen MB, Madsbad S, Holst JJ. Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients. Diabetes Care 1999; 22: 1137-1143.
    • (1999) Diabetes Care , vol.22 , pp. 1137-1143
    • Toft-Nielsen, M.B.1    Madsbad, S.2    Holst, J.J.3
  • 91
    • 0037667613 scopus 로고    scopus 로고
    • Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes.
    • Meier JJ, Gallwitz B, Salmen S et al. Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes. J Clin Endocrinol Metab 2003; 88: 2719-2725.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2719-2725
    • Meier, J.J.1    Gallwitz, B.2    Salmen, S.3
  • 92
    • 0027248866 scopus 로고
    • Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.
    • Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W. Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1993; 36: 741-744.
    • (1993) Diabetologia , vol.36 , pp. 741-744
    • Nauck, M.A.1    Kleine, N.2    Orskov, C.3    Holst, J.J.4    Willms, B.5    Creutzfeldt, W.6
  • 93
    • 0031740718 scopus 로고    scopus 로고
    • Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients.
    • Nauck MA, Weber I, Bach I et al. Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients. Diabet Med 1998; 15: 937-945.
    • (1998) Diabet Med , vol.15 , pp. 937-945
    • Nauck, M.A.1    Weber, I.2    Bach, I.3
  • 94
    • 0031033531 scopus 로고    scopus 로고
    • Near-normalisation of diurnal glucose concentrations by continuous administration of glucagon-like peptide-1 (GLP-1) in subjects with NIDDM.
    • Rachman J, Barrow BA, Levy JC, Turner RC. Near-normalisation of diurnal glucose concentrations by continuous administration of glucagon-like peptide-1 (GLP-1) in subjects with NIDDM. Diabetologia 1997; 40: 205-211.
    • (1997) Diabetologia , vol.40 , pp. 205-211
    • Rachman, J.1    Barrow, B.A.2    Levy, J.C.3    Turner, R.C.4
  • 96
    • 77951623571 scopus 로고    scopus 로고
    • Effects of exogenous glucagon-like peptide-1 on gastric emptying and glucose absorption in the critically ill: relationship to glycemia.
    • Deane AM, Chapman MJ, Fraser RJ et al. Effects of exogenous glucagon-like peptide-1 on gastric emptying and glucose absorption in the critically ill: relationship to glycemia. Crit Care Med 2010; 38: 1261-1269.
    • (2010) Crit Care Med , vol.38 , pp. 1261-1269
    • Deane, A.M.1    Chapman, M.J.2    Fraser, R.J.3
  • 97
    • 0141669196 scopus 로고    scopus 로고
    • Effects of 3 months of continuous subcutaneous administration of glucagon-like peptide 1 in elderly patients with type 2 diabetes.
    • Meneilly GS, Greig N, Tildesley H, Habener JF, Egan JM, Elahi D. Effects of 3 months of continuous subcutaneous administration of glucagon-like peptide 1 in elderly patients with type 2 diabetes. Diabetes Care 2003; 26: 2835-2841.
    • (2003) Diabetes Care , vol.26 , pp. 2835-2841
    • Meneilly, G.S.1    Greig, N.2    Tildesley, H.3    Habener, J.F.4    Egan, J.M.5    Elahi, D.6
  • 98
    • 0037045845 scopus 로고    scopus 로고
    • Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study.
    • Zander M, Madsbad S, Madsen JL, Holst JJ. Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study. Lancet 2002; 359: 824-830.
    • (2002) Lancet , vol.359 , pp. 824-830
    • Zander, M.1    Madsbad, S.2    Madsen, J.L.3    Holst, J.J.4
  • 99
    • 85075544941 scopus 로고    scopus 로고
    • Efficacy and safety of continuous, intravenous glucagon-like-peptide 1 (GLP-1) in comparison to insulin infusion for normalisation of hyperglycaemia in patients with type 2 diabetes (Abstract).
    • Diabetic Angiopathy Research Group.
    • Schmoelzer I, Kettler-Schmutt E, Pressl H, Sourij I, Wascher TC. Diabetic Angiopathy Research Group. Efficacy and safety of continuous, intravenous glucagon-like-peptide 1 (GLP-1) in comparison to insulin infusion for normalisation of hyperglycaemia in patients with type 2 diabetes (Abstract). Diabetologia 2007; 50(Suppl. 1): S351.
    • (2007) Diabetologia , vol.50 , Issue.SUPPL.. 1
    • Schmoelzer, I.1    Kettler-Schmutt, E.2    Pressl, H.3    Sourij, I.4    Wascher, T.C.5
  • 100
    • 34547930879 scopus 로고    scopus 로고
    • Effect of glucagon-like peptide-1 (GLP-1) on glycemic control and left ventricular function in patients undergoing coronary artery bypass grafting.
    • Sokos GG, Bolukoglu H, German J et al. Effect of glucagon-like peptide-1 (GLP-1) on glycemic control and left ventricular function in patients undergoing coronary artery bypass grafting. Am J Cardiol 2007; 100: 824-829.
    • (2007) Am J Cardiol , vol.100 , pp. 824-829
    • Sokos, G.G.1    Bolukoglu, H.2    German, J.3
  • 101
    • 43249089631 scopus 로고    scopus 로고
    • Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways.
    • Ban K, Noyan-Ashraf MH, Hoefer J, Bolz SS, Drucker DJ, Husain M. Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways. Circulation 2008; 117: 2340-2350.
    • (2008) Circulation , vol.117 , pp. 2340-2350
    • Ban, K.1    Noyan-Ashraf, M.H.2    Hoefer, J.3    Bolz, S.S.4    Drucker, D.J.5    Husain, M.6
  • 102
    • 51749088973 scopus 로고    scopus 로고
    • Effects of intravenous glucagon-like peptide-1 on glucose control and hemodynamics after coronary artery bypass surgery in patients with type 2 diabetes.
    • Mussig K, Oncu A, Lindauer P et al. Effects of intravenous glucagon-like peptide-1 on glucose control and hemodynamics after coronary artery bypass surgery in patients with type 2 diabetes. Am J Cardiol 2008; 102: 646-647.
    • (2008) Am J Cardiol , vol.102 , pp. 646-647
    • Mussig, K.1    Oncu, A.2    Lindauer, P.3
  • 103
    • 0842281595 scopus 로고    scopus 로고
    • Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1.
    • Nauck MA, Walberg J, Vethacke A et al. Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1. Regul Pept 2004; 118: 89-97.
    • (2004) Regul Pept , vol.118 , pp. 89-97
    • Nauck, M.A.1    Walberg, J.2    Vethacke, A.3
  • 104
    • 67249124672 scopus 로고    scopus 로고
    • The effect of exogenous glucagon-like peptide-1 on the glycaemic response to small intestinal nutrient in the critically ill: a randomised double-blind placebo-controlled cross over study.
    • Deane AM, Chapman MJ, Fraser RJ, Burgstad CM, Besanko LK, Horowitz M. The effect of exogenous glucagon-like peptide-1 on the glycaemic response to small intestinal nutrient in the critically ill: a randomised double-blind placebo-controlled cross over study. Crit Care 2009; 13: R67.
    • (2009) Crit Care , vol.13
    • Deane, A.M.1    Chapman, M.J.2    Fraser, R.J.3    Burgstad, C.M.4    Besanko, L.K.5    Horowitz, M.6
  • 105
    • 33749589088 scopus 로고    scopus 로고
    • Exenatide: a new option for the treatment of type 2 diabetes.
    • Yoo BK, Triller DM, Yoo DJ. Exenatide: a new option for the treatment of type 2 diabetes. Ann Pharmacother 2006; 40: 1777-1784.
    • (2006) Ann Pharmacother , vol.40 , pp. 1777-1784
    • Yoo, B.K.1    Triller, D.M.2    Yoo, D.J.3
  • 106
    • 27744541052 scopus 로고    scopus 로고
    • Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes.
    • Fehse F, Trautmann M, Holst JJ et al. Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab 2005; 90: 5991-5997.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5991-5997
    • Fehse, F.1    Trautmann, M.2    Holst, J.J.3
  • 107
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP.
    • Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007; 132: 2131-2157.
    • (2007) Gastroenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 108
    • 70350475695 scopus 로고    scopus 로고
    • Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors.
    • Neumiller JJ. Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors. J Am Pharm Assoc (2003) 2009; 49(Suppl. 1): S16-S29.
    • (2009) J Am Pharm Assoc (2003) , vol.49 , Issue.SUPPL.. 1
    • Neumiller, J.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.