Prevalence of elevated hemoglobin A1c among patients admitted to the hospital without a diagnosis of diabetes

Journal of Clinical Endocrinology and Metabolism

Volumn 93, Issue 11, 2008, Pages 4238-4244

  Wexler, Deborah J ^a   Nathan, David M ^a   Grant, Richard W ^a   Regan, Susan ^a   Van Leuvan, Allison L ^a   Cagliero, Enrico ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HEALTH CARE COST; HOSPITAL ADMISSION; HOSPITAL PATIENT; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PREVALENCE; PRIORITY JOURNAL;

EID: 57349171546     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-1090     Document Type: Article

References (40)

1. Aubert RE, Geiss LS, Ballard DJ, Cocanougher B, Herman WH 1995 Diabetes-related hospitalization and hospital utilization. In: Diabetes in America. 2nd ed. Bethesda, MD: National Institutes of Health; 553-569
2. Baker EH, Janaway CH, Philips BJ, Brennan AL, Baines DL, Wood DM, Jones PW 2006 Hyperglycaemia is associated with poor outcomes in patients admitted to hospital with acute exacerbations of chronic obstructive pulmonary disease. Thorax 61:284-289
3. Kosiborod M, Rathore SS, Inzucchi SE, Masoudi FA, Wang Y, Havranek EP, Krumholz HM 2005 Admission glucose and mortality in elderly patients hospitalized with acute myocardial infarction: implications for patients with and without recognized diabetes. Circulation 111:3078-3086
4. Umpierrez GE, Isaacs SD, Bazargan N, You X, Thaler LM, Kitabchi AE 2002 Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes. J Clin Endocrinol Metab 87:978-982
5. Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC 2001 Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke 32:2426-2432
6. Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R 2001 Intensive insulin therapy in the critically ill patients. N Engl J Med 345:1359-1367
7. Malmberg K 1997 Prospective randomised study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in Acute Myocardial Infarction) Study Group. BMJ 314:1512-1515
8. The ACE/ADA Task Force on Inpatient Diabetes 2006 American College of Endocrinology and American Diabetes Association Consensus Statement on Inpatient Diabetes and Glycemic Control: a call to action. Diabetes Care 29:1955-1962.
9. Society of Hospital Medicine Glycemic Control Task Force, Workbook for improvement: improving glycemic control, preventing hypoglycemia, and optimizing care of the inpatient with hyperglycemia and diabetes. http://www.hospitalmedicineorg/ResourceRoomRedesign/pdf/GC_Workbookpdf, accessed July 16, 2007
10. Joint Commission on Accreditation of Healthcare Organizations 2006 American Diabetes Association and Joint Commission collaborate on Joint Commission Inpatient Diabetes Care Certification. http://www.jointcommissionorg/ NewsRoom/NewsReleases/jc_nr_072006htm, accessed January 10, 2007
11. Kohner EM, Aldington SJ, Stratton IM, Manley SE, Holman RR, Matthews DR, Turner RC 1998 United Kingdom Prospective Diabetes Study, 30: diabetic retinopathy at diagnosis of non-insulin-dependent diabetes mellitus and associated risk factors. Arch Ophthalmol 116:297-303
12. Spijkerman AM, Dekker JM, Nijpels G, Adriaanse MC, Kostense PJ, Ruwaard D, Stehouwer CD, Bouter LM, Heine RJ 2003 Microvascular complications at time of diagnosis of type 2 diabetes are similar among diabetic patients detected by targeted screening and patients newly diagnosed in general practice: the Hoorn screening study. Diabetes Care 26:2604-2608
13. Koopman RJ, Mainous 3rd AG, Liszka HA, Colwell JA, Slate EH, Carnemolla MA, Everett CJ 2006 Evidence of nephropathy and peripheral neuropathy in US adults with undiagnosed diabetes. Ann Fam Med 4:427-432
14. Levetan CS, Passaro M, Jablonski K, Kass M, Ratner RE 1998 Unrecognized diabetes among hospitalized patients. Diabetes Care 21:246-249
15. Carral F, Olveira G, Aguilar M, Ortego J, Gavilan I, Domenech I, Escobar L 2003 Hospital discharge records under-report the prevalence of diabetes in inpatients. Diabetes Res Clin Pract 59:145-151
16. Lankisch M, Futh R, Gulker H, Lapp H, Bufe A, Haastert B, Martin S, Rathmann W 2008 Screening for undiagnosed diabetes in patients with acute myocardial infarction. Clin Res Cardiol, in press
17. Greci LS, Kailasam M, Malkani S, Katz DL, Hulinsky I, Ahmadi R, Nawaz H 2003 Utility of HbA1c levels for diabetes: case finding in hospitalized patients with hyperglycemia. Diabetes Care 26:1064-1068
18. Rohlfing CL, Little RR, Wiedmeyer HM, England JD, Madsen R, Harris MI, Flegal KM, Eberhardt MS, Goldstein DE 2000 Use of GHb (HbA1c) in screening for undiagnosed diabetes in the U.S. population. Diabetes Care 23:187-191
19. Buell C, Kermah D, Davidson MB 2007 Utility of A1C for diabetes screening in the 1999-2004 NHANES population. Diabetes Care 30:2233-2235
20. Cely CM, Arora P, Quartin AA, Kett DH, Schein RM 2004 Relationship of baseline glucose homeostasis to hyperglycemia during medical critical illness. Chest 126:879-887
21. Centers for Disease Control and Prevention (CDC) 2003 Prevalence of diabetes and impaired fasting glucose in adults: United States, 1999-2000 MMWR Morb Mortal Wkly Rep 52:833-837
22. Edelman D, Olsen MK, Dudley TK, Harris AC, Oddone EZ 2004 Utility of hemoglobin A1c in predicting diabetes risk. J Gen Intern Med 19:1175-1180
23. Goldstein DE, Little RR, Lorenz RA, Malone JI, Nathan D, Peterson CM, Sacks DB 2004 Tests of glycemia in diabetes. Diabetes Care 27:1761-1773
24. Little RR, Rohlfing CL, Wiedmeyer HM, Myers GL, Sacks DB, Goldstein DE 2001 The national glycohemoglobin standardization program: a five-year progress report. Clin Chem 47:1985-1992
25. Charlson ME, Pompei P, Ales KL, MacKenzie CR 1987 A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373-383
26. American Diabetes Association 2008 Standards of medical care in diabetes: 2008. Diabetes Care 31:S12-S54
27. Kopelman TR, O'Neill PJ, Kanneganti SR, Davis KM, Drachman DA 2008 The relationship of plasma glucose and glycosylated hemoglobin A1C levels among nondiabetic trauma patients. J Trauma 64:30-33; discussion 33-34
28. Wexler DJ, Meigs JB, Cagliero E, Nathan DM, Grant RW 2007 Prevalence of hyper- and hypoglycemia among inpatients with diabetes. Diabetes Care 30:367-369
29. Johnson SL, Tabaei BP, Herman WH 2005 The efficacy and cost of alternative strategies for systematic screening for type 2 diabetes in the U.S. population 45-74 years of age. Diabetes Care 28:307-311
30. Kornum JB, Thomsen RW, Riis A, Lervang HH, Schonheyder HC, Sorensen HT 2007 Type 2 diabetes and pneumonia outcomes: a population-based cohort study. Diabetes Care 30:2251-2257
31. Malmberg K, Norhammar A, Wedel H, Ryden L 1999 Glycometabolic state at admission: important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: long-term results from the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) study. Circulation 99:2626-2632
32. Krinsley JS 2003 Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients. Mayo Clin Proc 78:1471-1478
33. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM; Diabetes Prevention Program Research Group 2002 Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393-403
34. Pani LN, Nathan DM, Grant RW 2007 Clinical predictors of disease progression and medication initiation in untreated patients with type 2 diabetes and A1C less than 7%. Diabetes Care31:386-390
35. Ratner R, Goldberg R, Haffner S, Marcovina S, Orchard T, Fowler S, Temprosa M; Diabetes Prevention Program Research Group 2005 Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the Diabetes Prevention Program. Diabetes Care 28:888-894
36. 1998 Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet [Erratum (1998) 352:1558] 352:854-865
37. 1998 Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet [Erratum (1999) 354:602] 352:837-853
38. Kripalani S, LeFevre F, Phillips CO, Williams MV, Basaviah P, Baker DW 2007 Deficits in communication and information transfer between hospital-based and primary care physicians: implications for patient safety and continuity of care. JAMA 297:831-841
39. Edelman D 2002 Outpatient diagnostic errors: unrecognized hyperglycemia. Eff Clin Pract 5:11-16
40. George PM, Valabhji J, Dawood M, Henry JA 2005 Screening for type 2 diabetes in the accident and emergency department. Diabet Med 22:1766-1769