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Volumn 300, Issue 1, 2011, Pages

The Rac1/JNK pathway is critical for EGFR-dependent barrier formation in human airway epithelial cells

Author keywords

Airway epithelial cells; Transepithelial electrical resistance

Indexed keywords

DEXTRAN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; OCCLUDIN; RAC1 PROTEIN;

EID: 78650633257     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00159.2010     Document Type: Article
Times cited : (45)

References (28)
  • 1
    • 0028281588 scopus 로고
    • The role of growth factors in gastrointestinal cell proliferation
    • Alison MR, Sarraf CE. The role of growth factors in gastrointestinal cell proliferation. Cell Biol Int 18: 1-10, 1994.
    • (1994) Cell Biol Int , vol.18 , pp. 1-10
    • Alison, M.R.1    Sarraf, C.E.2
  • 2
    • 38049028580 scopus 로고    scopus 로고
    • Epidermal growth factor stimulates Rac1 and p21-activated kinase in vascular smooth muscle cells
    • Beier I, Dusing R, Vetter H, Schmitz U. Epidermal growth factor stimulates Rac1 and p21-activated kinase in vascular smooth muscle cells. Atherosclerosis 196: 92-97, 2008.
    • (2008) Atherosclerosis , vol.196 , pp. 92-97
    • Beier, I.1    Dusing, R.2    Vetter, H.3    Schmitz, U.4
  • 3
    • 8544250584 scopus 로고    scopus 로고
    • Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium
    • Burgel PR, Nadel JA. Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium. Thorax 59: 992-996, 2004.
    • (2004) Thorax , vol.59 , pp. 992-996
    • Burgel, P.R.1    Nadel, J.A.2
  • 5
    • 0032779202 scopus 로고    scopus 로고
    • The epidermal growth factor receptor and its ligand family: Their potential role in repair and remodelling in asthma
    • Davies DE, Polosa R, Puddicombe SM, Richter A, Holgate ST. The epidermal growth factor receptor and its ligand family: their potential role in repair and remodelling in asthma. Allergy 54: 771-783, 1999.
    • (1999) Allergy , vol.54 , pp. 771-783
    • Davies, D.E.1    Polosa, R.2    Puddicombe, S.M.3    Richter, A.4    Holgate, S.T.5
  • 6
    • 0032479299 scopus 로고    scopus 로고
    • A common requirement for the catalytic activity and both SH2 domains of SHP-2 in mitogen-activated protein (MAP) kinase activation by the ErbB family of receptors. A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation
    • Deb TB, Wong L, Salomon DS, Zhou G, Dixon JE, Gutkind JS, Thompson SA, Johnson GR. A common requirement for the catalytic activity and both SH2 domains of SHP-2 in mitogen-activated protein (MAP) kinase activation by the ErbB family of receptors. A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation. J Biol Chem 273: 16643-16646, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 16643-16646
    • Deb, T.B.1    Wong, L.2    Salomon, D.S.3    Zhou, G.4    Dixon, J.E.5    Gutkind, J.S.6    Thompson, S.A.7    Johnson, G.R.8
  • 8
    • 18844460415 scopus 로고    scopus 로고
    • Signalling pathways leading to neuroblastoma differentiation after serum withdrawal: HDL blocks neuroblastoma differentiation by inhibition of EGFR
    • Evangelopoulos ME, Weis J, Kruttgen A. Signalling pathways leading to neuroblastoma differentiation after serum withdrawal: HDL blocks neuroblastoma differentiation by inhibition of EGFR. Oncogene 24: 3309-3318, 2005.
    • (2005) Oncogene , vol.24 , pp. 3309-3318
    • Evangelopoulos, M.E.1    Weis, J.2    Kruttgen, A.3
  • 9
    • 7244257577 scopus 로고    scopus 로고
    • Epidermal growth factor-stimulated intestinal epithelial cell migration requires Src family kinase-dependent p38 MAPK signaling
    • Frey MR, Golovin A, Polk DB. Epidermal growth factor-stimulated intestinal epithelial cell migration requires Src family kinase-dependent p38 MAPK signaling. J Biol Chem 279: 44513-44521, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 44513-44521
    • Frey, M.R.1    Golovin, A.2    Polk, D.B.3
  • 10
    • 2442664118 scopus 로고    scopus 로고
    • Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
    • Gao Y, Dickerson JB, Guo F, Zheng J, Zheng Y. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc Natl Acad Sci USA 101: 7618-7623, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 7618-7623
    • Gao, Y.1    Dickerson, J.B.2    Guo, F.3    Zheng, J.4    Zheng, Y.5
  • 11
    • 0036088604 scopus 로고    scopus 로고
    • Rac1, but not RhoA, signaling protects epithelial adherens junction assembly during ATP depletion
    • Gopalakrishnan S, Dunn KW, Marrs JA. Rac1, but not RhoA, signaling protects epithelial adherens junction assembly during ATP depletion. Am J Physiol Cell Physiol 283: C261-C272, 2002.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Gopalakrishnan, S.1    Dunn, K.W.2    Marrs, J.A.3
  • 12
    • 0033575235 scopus 로고    scopus 로고
    • Shc regulates epidermal growth factor-induced activation of the JNK signaling pathway
    • Hashimoto A, Kurosaki M, Gotoh N, Shibuya M, Kurosaki T. Shc regulates epidermal growth factor-induced activation of the JNK signaling pathway. J Biol Chem 274: 20139-20143, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 20139-20143
    • Hashimoto, A.1    Kurosaki, M.2    Gotoh, N.3    Shibuya, M.4    Kurosaki, T.5
  • 13
    • 36849031788 scopus 로고    scopus 로고
    • Epithelium dysfunction in asthma
    • quiz 1245-1246
    • Holgate ST. Epithelium dysfunction in asthma. J Allergy Clin Immunol 120: 1233-1244; quiz 1245-1246, 2007.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 1233-1244
    • Holgate, S.T.1
  • 14
    • 0033011603 scopus 로고    scopus 로고
    • The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma
    • Holgate ST, Lackie PM, Davies DE, Roche WR, Walls AF. The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma. Clin Exp Allergy 29, Suppl 2: 90-95, 1999.
    • (1999) Clin Exp Allergy , vol.29 , Issue.SUPPL 2 , pp. 90-95
    • Holgate, S.T.1    Lackie, P.M.2    Davies, D.E.3    Roche, W.R.4    Walls, A.F.5
  • 16
    • 33746815813 scopus 로고    scopus 로고
    • Serum deprivation induces a unique hypercontractile phenotype of cultured smooth muscle cells
    • Ma X, Wang Y, Stephens NL. Serum deprivation induces a unique hypercontractile phenotype of cultured smooth muscle cells. Am J Physiol Cell Physiol 274: C1206-C1214, 1998.
    • (1998) Am J Physiol Cell Physiol , vol.274
    • Ma, X.1    Wang, Y.2    Stephens, N.L.3
  • 17
    • 0141618355 scopus 로고    scopus 로고
    • EGF receptor mediates adhesion-dependent activation of the Rac GTPase: A role for phosphatidylinositol 3-kinase and Vav2
    • Marcoux N, Vuori K. EGF receptor mediates adhesion-dependent activation of the Rac GTPase: a role for phosphatidylinositol 3-kinase and Vav2. Oncogene 22: 6100-6106, 2003.
    • (2003) Oncogene , vol.22 , pp. 6100-6106
    • Marcoux, N.1    Vuori, K.2
  • 18
    • 0035721544 scopus 로고    scopus 로고
    • Role of epidermal growth factor receptor activation in regulating mucin synthesis
    • Nadel JA. Role of epidermal growth factor receptor activation in regulating mucin synthesis. Respir Res 2: 85-89, 2001.
    • (2001) Respir Res , vol.2 , pp. 85-89
    • Nadel, J.A.1
  • 19
    • 0035378557 scopus 로고    scopus 로고
    • The role of epidermal growth factor in mucus production
    • Nadel JA, Burgel PR. The role of epidermal growth factor in mucus production. Curr Opin Pharmacol 1: 254-258, 2001.
    • (2001) Curr Opin Pharmacol , vol.1 , pp. 254-258
    • Nadel, J.A.1    Burgel, P.R.2
  • 21
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26: 3291-3310, 2007.
    • (2007) Oncogene , vol.26 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 22
    • 36049034205 scopus 로고    scopus 로고
    • Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance
    • Singh AB, Sugimoto K, Dhawan P, Harris RC. Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance. Am J Physiol Cell Physiol 293: C1660-C1668, 2007.
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Singh, A.B.1    Sugimoto, K.2    Dhawan, P.3    Harris, R.C.4
  • 23
    • 36349008570 scopus 로고    scopus 로고
    • Juxtacrine activation of epidermal growth factor (EGF) receptor by membrane-anchored heparinbinding EGF-like growth factor protects epithelial cells from anoikis while maintaining an epithelial phenotype
    • Singh AB, Sugimoto K, Harris RC. Juxtacrine activation of epidermal growth factor (EGF) receptor by membrane-anchored heparinbinding EGF-like growth factor protects epithelial cells from anoikis while maintaining an epithelial phenotype. J Biol Chem 282: 32890-32901, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 32890-32901
    • Singh, A.B.1    Sugimoto, K.2    Harris, R.C.3
  • 24
    • 27644431814 scopus 로고    scopus 로고
    • Alternate paths from epidermal growth factor receptor to Akt in malignant versus nontransformed lung epithelial cells: ErbB3 versus Gab1
    • Sithanandam G, Smith GT, Fields JR, Fornwald LW, Anderson LM. Alternate paths from epidermal growth factor receptor to Akt in malignant versus nontransformed lung epithelial cells: ErbB3 versus Gab1. Am J Respir Cell Mol Biol 33: 490-499, 2005.
    • (2005) Am J Respir Cell Mol Biol , vol.33 , pp. 490-499
    • Sithanandam, G.1    Smith, G.T.2    Fields, J.R.3    Fornwald, L.W.4    Anderson, L.M.5
  • 26
    • 56749184887 scopus 로고    scopus 로고
    • Tight junction-based epithelial microenvironment and cell proliferation
    • Tsukita S, Yamazaki Y, Katsuno T, Tamura A. Tight junction-based epithelial microenvironment and cell proliferation. Oncogene 27: 6930-6938, 2008.
    • (2008) Oncogene , vol.27 , pp. 6930-6938
    • Tsukita, S.1    Yamazaki, Y.2    Katsuno, T.3    Tamura, A.4
  • 28
    • 31344467784 scopus 로고    scopus 로고
    • Essential role for Rac in heregulin beta1 mitogenic signaling: A mechanism that involves epidermal growth factor receptor and is independent of ErbB4
    • Yang C, Liu Y, Lemmon MA, Kazanietz MG. Essential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4. Mol Cell Biol 26: 831-842, 2006.
    • (2006) Mol Cell Biol , vol.26 , pp. 831-842
    • Yang, C.1    Liu, Y.2    Lemmon, M.A.3    Kazanietz, M.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.