메뉴 건너뛰기




Volumn 107, Issue 45, 2010, Pages 19444-19448

Properdin homeostasis requires turnover of the alternative complement pathway

Author keywords

C3; Innate immunity; Neutrophil; Regulators of complement activation

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT FACTOR D; PROPERDIN; SNAKE VENOM;

EID: 78650595289     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1006608107     Document Type: Article
Times cited : (3)

References (46)
  • 1
    • 0023890664 scopus 로고
    • Molecular organization and function of the complement system
    • Müller-Eberhard HJ (1988) Molecular organization and function of the complement system. Annu Rev Biochem 57:321-347.
    • (1988) Annu Rev Biochem , vol.57 , pp. 321-347
    • Müller-Eberhard, H.J.1
  • 2
    • 77953266787 scopus 로고    scopus 로고
    • The amplification loop of the complement pathways
    • Lachmann PJ (2009) The amplification loop of the complement pathways. Adv Immunol 104:115-149.
    • (2009) Adv Immunol , vol.104 , pp. 115-149
    • Lachmann, P.J.1
  • 4
    • 0000719411 scopus 로고
    • The properdin system and immunity. I. Demonstration and isolation of a new serum protein, properdin, and its role in immune phenomena
    • Pillemer L, et al. (1954) The properdin system and immunity. I. Demonstration and isolation of a new serum protein, properdin, and its role in immune phenomena. Science 120:279-285.
    • (1954) Science , vol.120 , pp. 279-285
    • Pillemer, L.1
  • 5
    • 0016703811 scopus 로고
    • Properdin: Binding to C3b and stabilization of the C3bdependent C3 convertase
    • Fearon DT, Austen KF (1975) Properdin: Binding to C3b and stabilization of the C3bdependent C3 convertase. J Exp Med 142:856-863.
    • (1975) J Exp Med , vol.142 , pp. 856-863
    • Fearon, D.T.1    Austen, K.F.2
  • 6
    • 34848864365 scopus 로고    scopus 로고
    • Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly
    • Spitzer D, Mitchell LM, Atkinson JP, Hourcade DE (2007) Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly. J Immunol 179:2600-2608.
    • (2007) J Immunol , vol.179 , pp. 2600-2608
    • Spitzer, D.1    Mitchell, L.M.2    Atkinson, J.P.3    Hourcade, D.E.4
  • 7
    • 48249124246 scopus 로고    scopus 로고
    • The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis
    • Kemper C, Mitchell LM, Zhang L, Hourcade DE (2008) The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis. Proc Natl Acad Sci USA 105:9023-9028.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9023-9028
    • Kemper, C.1    Mitchell, L.M.2    Zhang, L.3    Hourcade, D.E.4
  • 8
    • 47249130305 scopus 로고    scopus 로고
    • Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation
    • Xu W, et al. (2008) Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation. J Immunol 180: 7613-7621.
    • (2008) J Immunol , vol.180 , pp. 7613-7621
    • Xu, W.1
  • 9
    • 38349097639 scopus 로고    scopus 로고
    • Activator-specific requirement of properdin in the initiation and amplification of the alternative pathway complement
    • Kimura Y, Miwa T, Zhou L, Song WC (2008) Activator-specific requirement of properdin in the initiation and amplification of the alternative pathway complement. Blood 111:732-740.
    • (2008) Blood , vol.111 , pp. 732-740
    • Kimura, Y.1    Miwa, T.2    Zhou, L.3    Song, W.C.4
  • 10
    • 77952300688 scopus 로고    scopus 로고
    • Properdin: Emerging roles of a patternrecognition molecule
    • Kemper C, Atkinson JP, Hourcade DE (2010) Properdin: Emerging roles of a patternrecognition molecule. Annu Rev Immunol 28:131-155.
    • (2010) Annu Rev Immunol , vol.28 , pp. 131-155
    • Kemper, C.1    Atkinson, J.P.2    Hourcade, D.E.3
  • 11
    • 0014878084 scopus 로고
    • Studies in vivo and in vitro on an abnormality in the metabolism of C3 in a patient with increased susceptibility to infection
    • Alper CA, Abramson N, Johnston RB, Jr., Jandl JH, Rosen FS (1970) Studies in vivo and in vitro on an abnormality in the metabolism of C3 in a patient with increased susceptibility to infection. J Clin Invest 49:1975-1985.
    • (1970) J Clin Invest , vol.49 , pp. 1975-1985
    • Alper, C.A.1    Abramson, N.2    Johnston Jr., R.B.3    Jandl, J.H.4    Rosen, F.S.5
  • 12
    • 0016651715 scopus 로고
    • Restoration by purified C3b inactivator of complement-mediated function in vivo in a patient with C3b inactivator deficiency
    • Ziegler JB, Alper CA, Rosen RS, Lachmann PJ, Sherington L (1975) Restoration by purified C3b inactivator of complement-mediated function in vivo in a patient with C3b inactivator deficiency. J Clin Invest 55:668-672.
    • (1975) J Clin Invest , vol.55 , pp. 668-672
    • Ziegler, J.B.1    Alper, C.A.2    Rosen, R.S.3    Lachmann, P.J.4    Sherington, L.5
  • 13
    • 0001727641 scopus 로고
    • A familial deficiency of complement factor H
    • Lopez-Larrea C, et al. (1987) A familial deficiency of complement factor H. Biochem Soc Trans 15:648-649.
    • (1987) Biochem Soc Trans , vol.15 , pp. 648-649
    • Lopez-Larrea, C.1
  • 14
    • 0022904646 scopus 로고
    • H deficiency in two brothers with atypical dense intramembranous deposit disease
    • Levy M, et al. (1986) H deficiency in two brothers with atypical dense intramembranous deposit disease. Kidney Int 30:949-956.
    • (1986) Kidney Int , vol.30 , pp. 949-956
    • Levy, M.1
  • 15
    • 0019387503 scopus 로고
    • Hypocomplementaemia due to a genetic deficiency of beta 1H globulin
    • Thompson RA, Winterborn MH (1981) Hypocomplementaemia due to a genetic deficiency of beta 1H globulin. Clin Exp Immunol 46:110-119.
    • (1981) Clin Exp Immunol , vol.46 , pp. 110-119
    • Thompson, R.A.1    Winterborn, M.H.2
  • 16
    • 0036699540 scopus 로고    scopus 로고
    • Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H
    • Pickering MC, et al. (2002) Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat Genet 31:424-428.
    • (2002) Nat Genet , vol.31 , pp. 424-428
    • Pickering, M.C.1
  • 17
    • 0028952777 scopus 로고
    • Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency
    • Høgåsen K, Jansen JH, Mollnes TE, Hovdenes J, Harboe M (1995) Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency. J Clin Invest 95:1054-1061.
    • (1995) J Clin Invest , vol.95 , pp. 1054-1061
    • Høgåsen, K.1    Jansen, J.H.2    Mollnes, T.E.3    Hovdenes, J.4    Harboe, M.5
  • 18
    • 53149126901 scopus 로고    scopus 로고
    • Membrane protein Crry maintains homeostasis of the complement system
    • Wu X, et al. (2008) Membrane protein Crry maintains homeostasis of the complement system. J Immunol 181:2732-2740.
    • (2008) J Immunol , vol.181 , pp. 2732-2740
    • Wu, X.1
  • 19
    • 59249091655 scopus 로고    scopus 로고
    • Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury
    • Ruseva MM, et al. (2009) Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury. Mol Immunol 46:803-811.
    • (2009) Mol Immunol , vol.46 , pp. 803-811
    • Ruseva, M.M.1
  • 20
    • 33750458032 scopus 로고    scopus 로고
    • DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity
    • Miwa T, et al. (2007) DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity. Mol Immunol 44:139-146.
    • (2007) Mol Immunol , vol.44 , pp. 139-146
    • Miwa, T.1
  • 21
    • 0027259139 scopus 로고
    • Properdin, a positive regulator of complement activation, is expressed in human T cell lines and peripheral blood T cells
    • Schwaeble W, et al. (1993) Properdin, a positive regulator of complement activation, is expressed in human T cell lines and peripheral blood T cells. J Immunol 151: 2521-2528.
    • (1993) J Immunol , vol.151 , pp. 2521-2528
    • Schwaeble, W.1
  • 22
    • 0028105814 scopus 로고
    • Expression of properdin in human monocytes
    • Schwaeble W, et al. (1994) Expression of properdin in human monocytes. Eur J Biochem 219:759-764.
    • (1994) Eur J Biochem , vol.219 , pp. 759-764
    • Schwaeble, W.1
  • 23
    • 0024555360 scopus 로고
    • Biosynthesis of properdin
    • Farries TC, Atkinson JP (1989) Biosynthesis of properdin. J Immunol 142:842-847.
    • (1989) J Immunol , vol.142 , pp. 842-847
    • Farries, T.C.1    Atkinson, J.P.2
  • 24
    • 0031135489 scopus 로고    scopus 로고
    • Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils
    • Wirthmueller U, et al. (1997) Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils. J Immunol 158:4444-4451.
    • (1997) J Immunol , vol.158 , pp. 4444-4451
    • Wirthmueller, U.1
  • 25
    • 0021799978 scopus 로고
    • P65: A C3b-binding protein on murine cells that shares antigenic determinants with the human C3b receptor (CR1) and is distinct from murine C3b receptor
    • Wong WW, Fearon DT (1985) p65: A C3b-binding protein on murine cells that shares antigenic determinants with the human C3b receptor (CR1) and is distinct from murine C3b receptor. J Immunol 134:4048-4056.
    • (1985) J Immunol , vol.134 , pp. 4048-4056
    • Wong, W.W.1    Fearon, D.T.2
  • 26
    • 0028954469 scopus 로고
    • Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein
    • Kim YU, et al. (1995) Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein. J Exp Med 181:151-159.
    • (1995) J Exp Med , vol.181 , pp. 151-159
    • Kim, Y.U.1
  • 27
    • 0034695647 scopus 로고    scopus 로고
    • A critical role for murine complement regulator Crry in fetomaternal tolerance
    • Xu C, et al. (2000) A critical role for murine complement regulator Crry in fetomaternal tolerance. Science 287:498-501.
    • (2000) Science , vol.287 , pp. 498-501
    • Xu, C.1
  • 28
    • 0347480217 scopus 로고    scopus 로고
    • Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway
    • Mao D, et al. (2003) Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway. Immunity 19:813-822.
    • (2003) Immunity , vol.19 , pp. 813-822
    • Mao, D.1
  • 29
    • 0014696581 scopus 로고
    • Complement-immunoglobulin relation: Deficiency of C'1q associated with impaired immunoglobulin G synthesis
    • Kohler PF, Müller-Eberhard HJ (1969) Complement-immunoglobulin relation: Deficiency of C'1q associated with impaired immunoglobulin G synthesis. Science 163: 474-475.
    • (1969) Science , vol.163 , pp. 474-475
    • Kohler, P.F.1    Müller-Eberhard, H.J.2
  • 30
    • 0015324502 scopus 로고
    • Metabolism of human C1q. Studies in hypogammaglobulinemia, myeloma, and systemic lupus erythematosus
    • Kohler PF, Müller-Eberhard HJ (1972) Metabolism of human C1q. Studies in hypogammaglobulinemia, myeloma, and systemic lupus erythematosus. J Clin Invest 51:868-875.
    • (1972) J Clin Invest , vol.51 , pp. 868-875
    • Kohler, P.F.1    Müller-Eberhard, H.J.2
  • 31
    • 0017854669 scopus 로고
    • Reduced concentrations of the first component of complement in hypotammaglobulinemia: Correction of infusion of gamma-globulin
    • Atkinson JP, Fisher FI, Reinhardt R, Frank MM (1978) Reduced concentrations of the first component of complement in hypotammaglobulinemia: Correction of infusion of gamma-globulin. Clin Immunol Immunopathol 9:350-355.
    • (1978) Clin Immunol Immunopathol , vol.9 , pp. 350-355
    • Atkinson, J.P.1    Fisher, F.I.2    Reinhardt, R.3    Frank, M.M.4
  • 32
    • 0024696429 scopus 로고
    • Localization of the properdin structural locus to Xp11.23-Xp21.1
    • Goundis D, Holt SM, Boyd Y, Reid KB (1989) Localization of the properdin structural locus to Xp11.23-Xp21.1. Genomics 5:56-60.
    • (1989) Genomics , vol.5 , pp. 56-60
    • Goundis, D.1    Holt, S.M.2    Boyd, Y.3    Reid, K.B.4
  • 33
    • 12644280801 scopus 로고    scopus 로고
    • Abrogation of the alternative complement pathway by targeted deletion of murine factor B
    • Matsumoto M, et al. (1997) Abrogation of the alternative complement pathway by targeted deletion of murine factor B. Proc Natl Acad Sci USA 94:8720-8725.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8720-8725
    • Matsumoto, M.1
  • 34
    • 0035807813 scopus 로고    scopus 로고
    • Complement activation in factor D-deficient mice
    • Xu Y, et al. (2001) Complement activation in factor D-deficient mice. Proc Natl Acad Sci USA 98:14577-14582.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14577-14582
    • Xu, Y.1
  • 35
    • 0034665297 scopus 로고    scopus 로고
    • -/-mice is rescued by adjuvants without improvement in germinal center development
    • Wu X, et al. (2000) Impaired affinity maturation in Cr2-/-mice is rescued by adjuvants without improvement in germinal center development. J Immunol 165:3119-3127.
    • (2000) J Immunol , vol.165 , pp. 3119-3127
    • Wu, X.1
  • 36
    • 0035253577 scopus 로고    scopus 로고
    • Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma
    • Drouin SM, et al. (2001) Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma. J Immunol 166:2025-2032.
    • (2001) J Immunol , vol.166 , pp. 2025-2032
    • Drouin, S.M.1
  • 37
    • 0024401548 scopus 로고
    • Factor C3f is a spasmogenic fragment released from C3b by factors I and H: The heptadeca-peptide C3f was synthesized and characterized
    • Ganu VS, Müller-Eberhard HJ, Hugli TE (1989) Factor C3f is a spasmogenic fragment released from C3b by factors I and H: The heptadeca-peptide C3f was synthesized and characterized. Mol Immunol 26:939-948.
    • (1989) Mol Immunol , vol.26 , pp. 939-948
    • Ganu, V.S.1    Müller-Eberhard, H.J.2    Hugli, T.E.3
  • 38
    • 34447548992 scopus 로고    scopus 로고
    • Comprehensive investigation of disease-specific short peptides in sera from patients with systemic sclerosis: Complement C3f-des-arginine, detected predominantly in systemic sclerosis sera, enhances proliferation of vascular endothelial cells
    • Xiang Y, et al. (2007) Comprehensive investigation of disease-specific short peptides in sera from patients with systemic sclerosis: Complement C3f-des-arginine, detected predominantly in systemic sclerosis sera, enhances proliferation of vascular endothelial cells. Arthritis Rheum 56:2018-2030.
    • (2007) Arthritis Rheum , vol.56 , pp. 2018-2030
    • Xiang, Y.1
  • 39
    • 18144454192 scopus 로고    scopus 로고
    • Targeted and restricted complement activation on acrosome-reacted spermatozoa
    • Riley-Vargas RC, Lanzendorf S, Atkinson JP (2005) Targeted and restricted complement activation on acrosome-reacted spermatozoa. J Clin Invest 115:1241-1249.
    • (2005) J Clin Invest , vol.115 , pp. 1241-1249
    • Riley-Vargas, R.C.1    Lanzendorf, S.2    Atkinson, J.P.3
  • 40
    • 35348928319 scopus 로고    scopus 로고
    • Anaphylatoxins: Their role in bacterial infection and inflammation
    • Haas PJ, van Strijp J (2007) Anaphylatoxins: Their role in bacterial infection and inflammation. Immunol Res 37:161-175.
    • (2007) Immunol Res , vol.37 , pp. 161-175
    • Haas, P.J.1    Van Strijp, J.2
  • 41
    • 77954312934 scopus 로고    scopus 로고
    • Native polymeric forms of properdin selectively bind to targets and promote activation of the alternative pathway of complement
    • Ferreira VP, Cortes C, Pangburn MK (2010) Native polymeric forms of properdin selectively bind to targets and promote activation of the alternative pathway of complement. Immunobiology 215:932-940.
    • (2010) Immunobiology , vol.215 , pp. 932-940
    • Ferreira, V.P.1    Cortes, C.2    Pangburn, M.K.3
  • 42
    • 0033062148 scopus 로고    scopus 로고
    • Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA
    • Circolo A, et al. (1999) Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA. Immunopharmacology 42:135-149.
    • (1999) Immunopharmacology , vol.42 , pp. 135-149
    • Circolo, A.1
  • 43
    • 0029558338 scopus 로고
    • Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity
    • Wessels MR, et al. (1995) Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity. Proc Natl Acad Sci USA 92:11490-11494.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11490-11494
    • Wessels, M.R.1
  • 44
    • 0031778836 scopus 로고    scopus 로고
    • Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
    • Botto M, et al. (1998) Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 19:56-59.
    • (1998) Nat Genet , vol.19 , pp. 56-59
    • Botto, M.1
  • 45
    • 0033582228 scopus 로고    scopus 로고
    • Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting
    • Sun X, et al. (1999) Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting. Proc Natl Acad Sci USA 96:628-633.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 628-633
    • Sun, X.1
  • 46
    • 0029926153 scopus 로고    scopus 로고
    • Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2
    • Molina H, et al. (1996) Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2. Proc Natl Acad Sci USA 93:3357-3361.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3357-3361
    • Molina, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.