Systematic mutation and thermodynamic analysis of central tyrosine pairs in polyspecific NKG2D receptor interactions

Molecular Immunology

Volumn 48, Issue 4, 2011, Pages 516-523

  Culpepper, David J ^a   Maddox, Michael K ^a   Caldwell, Andrew B ^a   McFarland, Benjamin J ^a  

^a SEATTLE PACIFIC UNIVERSITY   (United States)

Author keywords

Killer lectin like receptors; Mutagenesis; Natural killer cell receptors; Polyspecific protein protein interactions; Van't Hoff thermodynamics

Indexed keywords

ALANINE; ISOLEUCINE; LEUCINE; NATURAL KILLER CELL RECEPTOR NKG2D; PHENYLALANINE; SERINE; TRYPTOPHAN; TYROSINE; VALINE;

ABSORPTION; ANTIGEN ANTIBODY REACTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; GENE MUTATION; HEAT; HUMAN; HYDROPHOBICITY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SUBSTITUTION REACTION; THERMODYNAMICS; WILD TYPE;

CRYSTALLOGRAPHY, X-RAY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIGANDS; MUTANT PROTEINS; MUTATION; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PROTEIN BINDING; SOLVENTS; THERMODYNAMICS; TYROSINE;

EID: 78650592121     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.10.007     Document Type: Article

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