The bioactivity of human bone morphogenetic protein-15 is sensitive to C-terminal modification: Characterization of the purified untagged processed mature region

Molecular and Cellular Endocrinology

Volumn 332, Issue 1-2, 2011, Pages 106-115

  Pulkki, Minna M ^a   Myllymaa, Samu ^a   Pasternack, Arja ^a   Lun, Stanley ^b   Ludlow, Helen ^c   Al Qahtani, Ahmed ^c   Korchynskyi, Olexandr ^d   Groome, Nigel ^c   Juengel, Jennifer L ^b   Kalkkinen, Nisse ^e   Laitinen, Mika ^f   Ritvos, Olli ^a   Mottershead, David G ^a,g  

^a UNIVERSITY OF HELSINKI   (Finland)

^b AGRESEARCH   (New Zealand)

^c OXFORD BROOKES UNIVERSITY   (United Kingdom)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF HELSINKI   (Finland)

^f Biotechvisions Ltd   (Finland)

^g UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

BMP15; Bone morphogenetic protein; Granulosa cell; Human

Indexed keywords

BONE MORPHOGENETIC PROTEIN 15; CELL DNA; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; INHIBIN B; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 15; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CELL STRAIN HEK293; CONTROLLED STUDY; DNA SYNTHESIS; GRANULOSA CELL; HUMAN; HUMAN CELL; LUTEAL CELL; MITOGENESIS; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RAT; REPORTER GENE; STORAGE TEMPERATURE;

ANIMALS; BONE MORPHOGENETIC PROTEIN 15; FEMALE; GENES, REPORTER; GROWTH DIFFERENTIATION FACTOR 9; HEK293 CELLS; HUMANS; LUTEAL CELLS; OOCYTES; RATS; TRANSFORMING GROWTH FACTOR BETA;

EID: 78650518658     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2010.10.002     Document Type: Article

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