Effects of Immunization Against Bone Morphogenetic Protein 15 and Growth Differentiation Factor 9 on Ovulation Rate, Fertilization, and Pregnancy in Ewes

Biology of Reproduction

Volumn 70, Issue 3, 2004, Pages 557-561

  Juengel, Jennifer L ^a   Hudson, Norma L ^a   Whiting, Lynda ^a   McNatty, Kenneth P ^a  

^a AGRESEARCH   (New Zealand)

Author keywords

Corpus luteum; Follicle; Growth factors; Ovary; Pregnancy

Indexed keywords

BONE MORPHOGENETIC PROTEIN 15; GROWTH DIFFERENTIATION FACTOR 9; KEYHOLE LIMPET HEMOCYANIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL HUSBANDRY; ARTICLE; CONTROLLED STUDY; CORPUS LUTEUM; EMBRYO; EMBRYO TRANSFER; ESTRUS CYCLE; FEMALE; FEMALE FERTILITY; FERTILIZATION; FETUS; FETUS DEVELOPMENT; IMMUNIZATION; MALE; MALE FERTILITY; MAMMAL; NONHUMAN; OOCYTE; OVULATION; PREGNANCY; PRIORITY JOURNAL; REGULATORY MECHANISM; SHEEP;

AMINO ACID SEQUENCE; ANIMALS; CROSS REACTIONS; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FERTILITY AGENTS, FEMALE; FERTILIZATION; IMMUNIZATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; OVULATION; PEPTIDE FRAGMENTS; PREGNANCY; PREGNANCY RATE; PREGNANCY, ANIMAL; PROGESTERONE; SHEEP;

ANIMALIA; MAMMALIA; OVIS; OVIS ARIES;

EID: 1242300111     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.103.023333     Document Type: Article

References (14)

1. Elvin JA, Yan C, Matzuk MM. At the cutting edge. Oocyte expressed TGFβ superfamily members in female fertility. Mol Cell Endocrinol 2000; 159:1-5.
2. McNatty KP, Juengel JL, Wilson T. Galloway SM, Davis GH, Hudson NL, Moeller CL, Cranfield M, Reader KL. Laitinen PME, Groome NP. Sawyer HR, Ritvos O. Oocyte-derived growth factors and ovulation rate in sheep. Reproduction 2003 (Suppl 61):S339-S351.
3. Dong J, Altertini DF, Nishimori K, Rajendra Kumar T, Lu N, Matzuk. MM. Growth differentiation factor-9 is required during early ovarian folliculogenesis. Nature 1996; 383:531-535.
4. Yan C, Wang P, DeMayo J, Demay FJ, Elvin JA, Carino C, Prasad SV, Skinner SS, Dunbar BS, Dube JL, Celeste AJ. Matzuk MM. Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. Mol Endocrinol 2001; 15:854-866.
5. Juengel JL, Hudson NL, Heath DA, Smith P, Reader KL, Lawrence SB, O'Connell AR, Laitinen MPE. Cranfield M, Groome NP, Ritvos O, McNatty KP. Growth differentiation factor 9 and bone morphogenetic protein 15 are essential for ovarian follicular development in sheep. Biol Reprod 2002; 67:1777-1789.
6. Carabatsos MJ, Levin J, Matzuk MM, Albertini. DF. Characterization of oocyte and follicle development in growth differentiation factor-9-deficient mice. Dev Biol 1998; 204:373-384.
7. Davis GH, McEwan JC, Fennessy PF, Dodds KG, Farquhar PA. Evidence for the presence of a major gene influencing ovulation rate on the X chromosome of sheep. Biol Reprod 1991; 44:620-640.
8. Galloway SM, McNatty KP, Cambridge LM, Laitinen MPE, Juengel JL, Jokiranta TS, McLaren RJ, Luiro K, Dodds KG, Montgomery GW, Beattie AE, Davis GH, Ritvos O. Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner. Nat Genet 2000; 25:279-283.
9. Davis GH, Bruce GD, Dodds KG. Ovulation rate and litter size of prolific Inverdale (FecXI) and Hanna (FecXH) sheep. Proc Assoc Adv Animal Breed Genet 2001; 14:175-178.
10. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol 1990; 215:403-410.
11. Smith P, O WS, Hudson NL, Shaw L, Heath DA, Condell L, Phillips DJ, McNatty KP. Effects of the Booroola gene (FecB) on body weight, ovarian development and hormone concentrations during fetal life. J Reprod Fertil 1993; 98:41-54.
12. McNatty KP, Gibb M, Dobson C, Thurley DC, Findlay JK. Changes in the concentration of gonadotropic and steroidal hormones in the antral fluid of ovarian follicles throughout the estrous cycle of sheep. Aust J Biol Sci 1981; 34:67-80.
13. Liao WX, Moore RK, Otsuka F, Shimasaki S. Effect of intracellular interactions on the processing and secretion of bone morphogenetic protein-15 (BMP-15) and growth and differentiation factor-9. Implication of the aberrant ovarian phenotype of BMP-15 mutant sheep. J Biol Chem 2003; 278:3713-3719.
14. Davis GH, Dodds KG, McEwan JC, Fennessy PF. Liveweight, fleece weight and prolificacy of Romney ewes carrying the Inverdale prolificacy gene (FecXI) located on the X-chromosome. Livest Prod Sci 1993; 34:83-91.