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Volumn 53, Issue 1, 2011, Pages 156-164

The effects of ginsenoside Rb1 on endothelial damage and ghrelin expression induced by hyperhomocysteine

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GHRELIN; GINSENOSIDE RB 1; HOMOCYSTEINE; HORMONE RECEPTOR BLOCKING AGENT; METHIONINE; NITRIC OXIDE; VON WILLEBRAND FACTOR;

EID: 78650518488     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2010.06.170     Document Type: Article
Times cited : (18)

References (37)
  • 1
    • 69149110615 scopus 로고    scopus 로고
    • Ginseng compounds: An update on their molecular mechanisms and medical applications
    • J.M. L, Q. Yao, and C. Chen Ginseng compounds: an update on their molecular mechanisms and medical applications Curr Vasc Pharmacol 7 2009 293 302
    • (2009) Curr Vasc Pharmacol , vol.7 , pp. 293-302
    • M, L.J.1    Yao, Q.2    Chen, C.3
  • 2
    • 77449133053 scopus 로고    scopus 로고
    • Therapeutic potential of ginseng root preparations in treating diabetes mellitus
    • E.B. Arushanian Therapeutic potential of ginseng root preparations in treating diabetes mellitus Eksp Klin Farmakol 72 2009 52 56
    • (2009) Eksp Klin Farmakol , vol.72 , pp. 52-56
    • Arushanian, E.B.1
  • 3
    • 0029853361 scopus 로고    scopus 로고
    • Cardiovascular protection by ginsenosides and their nitric oxide releasing action
    • X. Chen Cardiovascular protection by ginsenosides and their nitric oxide releasing action Clin Exp Pharmacol Physiol 23 1996 728 732
    • (1996) Clin Exp Pharmacol Physiol , vol.23 , pp. 728-732
    • Chen, X.1
  • 4
    • 4444239425 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of ginseng root for cardiovascular disease
    • W. Zhou, H. Chai, P.H. Lin, A.B. Lumsden, Q. Yao, and C.J. Chen Molecular mechanisms and clinical applications of ginseng root for cardiovascular disease Med Sci Monit 10 2004 187 192
    • (2004) Med Sci Monit , vol.10 , pp. 187-192
    • Zhou, W.1    Chai, H.2    Lin, P.H.3    Lumsden, A.B.4    Yao, Q.5    Chen, C.J.6
  • 5
    • 78650518154 scopus 로고    scopus 로고
    • Hyperhomocysteinemia induces endothelial dysfunction and aggravates microcirculation dysfunction and microthrombosis
    • J. Sun, H. Tan, C. Cheng, W. Wu, Y. Wu, and H. Sun Hyperhomocysteinemia induces endothelial dysfunction and aggravates microcirculation dysfunction and microthrombosis CJPP 23 2007 2336 2340
    • (2007) CJPP , vol.23 , pp. 2336-2340
    • Sun, J.1    Tan, H.2    Cheng, C.3    Wu, W.4    Wu, Y.5    Sun, H.6
  • 6
    • 78650522266 scopus 로고    scopus 로고
    • Effects of the typical herbal medicine for collaterals deoppilation on rats with endothelial dysfunction and the comparison with Tongxinluo
    • T. Lan, H. Tan, W. Wu, Y. Wu, J. Sun, and Y. Han Effects of the typical herbal medicine for collaterals deoppilation on rats with endothelial dysfunction and the comparison with Tongxinluo The 3rd Word Integrative Medicine Congress Abstracts 3 2007 184 185
    • (2007) The 3rd Word Integrative Medicine Congress Abstracts , vol.3 , pp. 184-185
    • Lan, T.1    Tan, H.2    Wu, W.3    Wu, Y.4    Sun, J.5    Han, Y.6
  • 7
  • 8
    • 2442515963 scopus 로고    scopus 로고
    • Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes
    • M.J. Iglesias, R. Pieiro, M. Blanco, R. Gallego, C. Diguez, and O. Gualillo Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes Cardiovasc Res 62 2004 481 488
    • (2004) Cardiovasc Res , vol.62 , pp. 481-488
    • Iglesias, M.J.1    Pieiro, R.2    Blanco, M.3    Gallego, R.4    Diguez, C.5    Gualillo, O.6
  • 9
    • 58749089263 scopus 로고    scopus 로고
    • Growth hormone-releasing peptide ghrelin inhibits homocysteine-induced endothelial dysfunction in porcine coronary arteries and human endothelial cells
    • N. Hedayati, S. Annambhotla, J. Jiang, X. Wang, H. Chai, and P.H. Lin Growth hormone-releasing peptide ghrelin inhibits homocysteine-induced endothelial dysfunction in porcine coronary arteries and human endothelial cells J Vasc Surg 49 2009 199 207
    • (2009) J Vasc Surg , vol.49 , pp. 199-207
    • Hedayati, N.1    Annambhotla, S.2    Jiang, J.3    Wang, X.4    Chai, H.5    Lin, P.H.6
  • 10
    • 18844457413 scopus 로고    scopus 로고
    • Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries
    • DOI 10.1016/j.jvs.2005.01.054, PII S0741521405002429
    • W. Zhou, H. Chai, P.H. Lin, A.B. Lumsden, Q. Yao, and C. Chen Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries J Vasc Surg 41 2005 861 868 (Pubitemid 40693810)
    • (2005) Journal of Vascular Surgery , vol.41 , Issue.5 , pp. 861-868
    • Zhou, W.1    Chai, H.2    Lin, P.H.3    Lumsden, A.B.4    Yao, Q.5    Chen, C.6
  • 11
    • 0032787873 scopus 로고    scopus 로고
    • Dysfunction of nitric oxide mediation in isolated rat arterioles with methionine diet-induced hyperhomocysteinemia
    • Z. Ungvari, P. Pacher, and K. Rischak Dysfunction of nitric oxide mediation in isolated rat arterioles with methionine diet-induced hyperhomocysteinemia Arterioscler Thromb Vasc Biol 19 1999 1899 1904
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1899-1904
    • Ungvari, Z.1    Pacher, P.2    Rischak, K.3
  • 12
    • 36049046075 scopus 로고    scopus 로고
    • A novel cultured tissue model of rat aorta: VSMC proliferation mechanism in relationship to atherosclerosis
    • C. Wang, Y. Zhang, Q. Yang, Y. Yang, Y. Gu, and M. Wang A novel cultured tissue model of rat aorta: VSMC proliferation mechanism in relationship to atherosclerosis Exp Mol Pathol 83 2007 453 458
    • (2007) Exp Mol Pathol , vol.83 , pp. 453-458
    • Wang, C.1    Zhang, Y.2    Yang, Q.3    Yang, Y.4    Gu, Y.5    Wang, M.6
  • 13
    • 11444264970 scopus 로고    scopus 로고
    • AT1 receptors and L-type calcium channels: Functional coupling in supersensitivity to angiotensin II in diabetic rats
    • K.H. Arun, C.L. Kaul, and P. Ramarao AT1 receptors and L-type calcium channels: functional coupling in supersensitivity to angiotensin II in diabetic rats Cardiovasc Res 65 2005 374 386
    • (2005) Cardiovasc Res , vol.65 , pp. 374-386
    • Arun, K.H.1    Kaul, C.L.2    Ramarao, P.3
  • 15
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth hormone releasing acylated peptide from stomach
    • M. Kojima, H. Hosoda, Y. Date, M. Nakazato, H. Matsuo, and K. Kangawa Ghrelin is a growth hormone releasing acylated peptide from stomach Nature 402 1999 656 660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 16
    • 0036963414 scopus 로고    scopus 로고
    • Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia
    • N. Weiss, C. Keller, U. Hoffmann, and J. Loscalzo Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia Vasc Me 7 2002 227 239
    • (2002) Vasc Me , vol.7 , pp. 227-239
    • Weiss, N.1    Keller, C.2    Hoffmann, U.3    Loscalzo, J.4
  • 17
    • 0036350569 scopus 로고    scopus 로고
    • Homocysteine decreases endothelium-dependent vaso-relaxation in porcine arteries
    • C. Chen, B.S. Conklin, Z. Ren, and D.S. Zhong Homocysteine decreases endothelium-dependent vaso-relaxation in porcine arteries J Surg Res 102 2002 22 30
    • (2002) J Surg Res , vol.102 , pp. 22-30
    • Chen, C.1    Conklin, B.S.2    Ren, Z.3    Zhong, D.S.4
  • 19
    • 0032832961 scopus 로고    scopus 로고
    • Effect of homocysteine on the production of nitric oxide in endothelial cells
    • K. Chow, F. Cheung, and T.T. Lao Effect of homocysteine on the production of nitric oxide in endothelial cells O K Clin Ex p Pharmacol Physiol 26 1999 817 818
    • (1999) Clin Ex P Pharmacol Physiol , vol.26 , pp. 817-818
    • Chow, K.1    Cheung, F.2    Lao, T.T.3
  • 20
    • 0036186652 scopus 로고    scopus 로고
    • Humoral markers of inflammation and endothelial dysfunction in relation to adiposity and in vivo insulin action in Pima Indians
    • C. Weyer, J.S. Yudkin, C.D. Stehouwer, C.G. Schalkwijk, R.E. Pratley, and P.A. Tataranni Humoral markers of inflammation and endothelial dysfunction in relation to adiposity and in vivo insulin action in Pima Indians Atherosclerosis 161 2002 233 242
    • (2002) Atherosclerosis , vol.161 , pp. 233-242
    • Weyer, C.1    Yudkin, J.S.2    Stehouwer, C.D.3    Schalkwijk, C.G.4    Pratley, R.E.5    Tataranni, P.A.6
  • 21
    • 33845352189 scopus 로고    scopus 로고
    • Ginseng saponins diminish adverse vascular effects associated with chronic methronine-induced hyperhomocysteinemia
    • J.H. Kim, S.Y. Cho, C.W. Kang, I.S. Yoon, J.H. Lee, and S.M. Jeong Ginseng saponins diminish adverse vascular effects associated with chronic methronine-induced hyperhomocysteinemia Biol Pharm Bull 29 2006 2425 2431
    • (2006) Biol Pharm Bull , vol.29 , pp. 2425-2431
    • Kim, J.H.1    Cho, S.Y.2    Kang, C.W.3    Yoon, I.S.4    Lee, J.H.5    Jeong, S.M.6
  • 22
    • 0034602359 scopus 로고    scopus 로고
    • Induction of inducible nitric oxide synthase by ginsenosides in cultured porcine endothelial cells
    • Z. Li, Y. Niwa, S. Sakamoto, M. Shono, X. Chen, and Y. Nakaya Induction of inducible nitric oxide synthase by ginsenosides in cultured porcine endothelial cells Life Sci 67 2000 2983 2989
    • (2000) Life Sci , vol.67 , pp. 2983-2989
    • Li, Z.1    Niwa, Y.2    Sakamoto, S.3    Shono, M.4    Chen, X.5    Nakaya, Y.6
  • 23
    • 0034747110 scopus 로고    scopus 로고
    • Involvement of Ca2+ -activated K+ channels in ginsenosides-induced aortic relaxation in rats
    • Z. Li, X. Chen, Y. Niwa, S. Sakamoto, and Y. Nakaya Involvement of Ca2+ -activated K+ channels in ginsenosides-induced aortic relaxation in rats J Cardiovasc Pharmacol 37 2001 41 47
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 41-47
    • Li, Z.1    Chen, X.2    Niwa, Y.3    Sakamoto, S.4    Nakaya, Y.5
  • 24
    • 78650524441 scopus 로고    scopus 로고
    • Effect of ginsenoside Rb1 and astragalus polysaccharide on the excretion of NO, IL-6 and TNF-α in micro-vascular endothelial cells
    • Xie Huimei, Hu Ge, and Suo Zhanwei Effect of ginsenoside Rb1 and astragalus polysaccharide on the excretion of NO, IL-6 and TNF-α in micro-vascular endothelial cells Acta Vet Zool Sin 37 2006 903 907
    • (2006) Acta Vet Zool Sin , vol.37 , pp. 903-907
    • Huimei, X.1    Ge, H.2    Zhanwei, S.3
  • 25
    • 78650519519 scopus 로고    scopus 로고
    • Effect of ginsenoside on gene expression profile associated with blood vessel endothelium injure of rats with deficiency of vital energy
    • Wu Yiling, Li Yanning, Qi Jinsheng, Jia Zhenhua, and Liu Kun Effect of ginsenoside on gene expression profile associated with blood vessel endothelium injure of rats with deficiency of vital energy Nat Prod Res Dev 19 2007 973 977
    • (2007) Nat Prod Res Dev , vol.19 , pp. 973-977
    • Yiling, W.1    Yanning, L.2    Jinsheng, Q.3    Zhenhua, J.4    Kun, L.5
  • 26
    • 70450225780 scopus 로고    scopus 로고
    • Ginsenoside Rb1 attenuates homocysteine augmented guidewire injury-induced intimal hyperplasia in mice
    • H. Chai, Y. Dong, X. Wang, and W. Zhou Ginsenoside Rb1 attenuates homocysteine augmented guidewire injury-induced intimal hyperplasia in mice J Surg Res 157 2009 193 198
    • (2009) J Surg Res , vol.157 , pp. 193-198
    • Chai, H.1    Dong, Y.2    Wang, X.3    Zhou, W.4
  • 27
    • 33646805400 scopus 로고    scopus 로고
    • Effects of homocyteine and ginsenoside Rb1 on endothelial proliferation and superoxide anion production
    • R. Ohashi, S. Yan, H. Mu, H. Chai, Q. Yao, and P.H. Lin Effects of homocyteine and ginsenoside Rb1 on endothelial proliferation and superoxide anion production J Surg Res 133 2006 89 94
    • (2006) J Surg Res , vol.133 , pp. 89-94
    • Ohashi, R.1    Yan, S.2    Mu, H.3    Chai, H.4    Yao, Q.5    Lin, P.H.6
  • 30
    • 0036109544 scopus 로고    scopus 로고
    • Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system
    • S.D. Katugampola, J.J. Maguire, R.E. Kuc, K.E. Wiley, and A.P. Davenport Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system Can J Physiol Pharmacol 80 2002 369 374
    • (2002) Can J Physiol Pharmacol , vol.80 , pp. 369-374
    • Katugampola, S.D.1    Maguire, J.J.2    Kuc, R.E.3    Wiley, K.E.4    Davenport, A.P.5
  • 31
    • 0036687932 scopus 로고    scopus 로고
    • Comparison of vasodilators in human internal mammary artery: Ghrelin is a potent physiological antagonist of endothelin-1
    • K.E. Wiley, and A.P. Davenport Comparison of vasodilators in human internal mammary artery: ghrelin is a potent physiological antagonist of endothelin-1 Br J Pharmacol 136 2002 1146 1152
    • (2002) Br J Pharmacol , vol.136 , pp. 1146-1152
    • Wiley, K.E.1    Davenport, A.P.2
  • 32
    • 4544253380 scopus 로고    scopus 로고
    • Ghrelin protects myocardium from isoproterenol-induced injury in rats
    • L. Chang, J. Zhao, G.Z. Li, B. Geng, C.S. Pan, and Y.F. Qi Ghrelin protects myocardium from isoproterenol-induced injury in rats Acta Pharmacol Sin 25 2004 1131 1137
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 1131-1137
    • Chang, L.1    Zhao, J.2    Li, G.Z.3    Geng, B.4    Pan, C.S.5    Qi, Y.F.6
  • 33
    • 20144377975 scopus 로고    scopus 로고
    • Ghrelin blunted vascular calcification in vivo and in vitro in rats
    • G.Z. Li, W. Jiang, J. Zhao, C.S. Pan, J. Cao, and C.S. Tang Ghrelin blunted vascular calcification in vivo and in vitro in rats Regul Pept 129 2005 167 176
    • (2005) Regul Pept , vol.129 , pp. 167-176
    • Li, G.Z.1    Jiang, W.2    Zhao, J.3    Pan, C.S.4    Cao, J.5    Tang, C.S.6
  • 34
    • 0035940390 scopus 로고    scopus 로고
    • Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: Relationships between ghrelin and anabolic/catabolic factors
    • N. Nagaya, M. Uematsu, M. Kojima, Y. Date, M. Nakazato, and H. Okumura Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic/catabolic factors Circulation 104 2001 2034 2038
    • (2001) Circulation , vol.104 , pp. 2034-2038
    • Nagaya, N.1    Uematsu, M.2    Kojima, M.3    Date, Y.4    Nakazato, M.5    Okumura, H.6
  • 35
    • 34247200939 scopus 로고    scopus 로고
    • Endogenous ghrelin increases in ADR-induced heart failure rats
    • Z. Xu, W. Wu, X. Zhang, and G. Liu Endogenous ghrelin increases in ADR-induced heart failure rats J Endocrinol Invest 30 2007 117 125
    • (2007) J Endocrinol Invest , vol.30 , pp. 117-125
    • Xu, Z.1    Wu, W.2    Zhang, X.3    Liu, G.4
  • 36
    • 42749093343 scopus 로고    scopus 로고
    • Growth hormone releasing peptide (ghrelin) inhibits doxorubicin induced cardiotoxicity through mitochondria mediated pathways
    • Z. Xu, S. Lin, W. Wu, H. Tan, Z. Wang, and C. Cheng Growth hormone releasing peptide (ghrelin) inhibits doxorubicin induced cardiotoxicity through mitochondria mediated pathways Toxicology 247 2008 133 138
    • (2008) Toxicology , vol.247 , pp. 133-138
    • Xu, Z.1    Lin, S.2    Wu, W.3    Tan, H.4    Wang, Z.5    Cheng, C.6
  • 37
    • 2442515963 scopus 로고    scopus 로고
    • Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes
    • M.J. Iglesias, R. Pieiro, M. Blanco, R. Gallego, C. Diguez, and O. Gualillo Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes Cardiovasc Res 62 2004 481 488
    • (2004) Cardiovasc Res , vol.62 , pp. 481-488
    • Iglesias, M.J.1    Pieiro, R.2    Blanco, M.3    Gallego, R.4    Diguez, C.5    Gualillo, O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.