Synthesis and biological activity of novel 5′-arylamino-nucleosides by microwave-assisted one-pot tandem Staudinger/aza-Wittig/reduction

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 1, 2011, Pages 574-576

  Chen, Hua ^a   Zhao, Jianpeng ^a   Li, Yanan ^a   Shen, Fengjuan ^a   Li, Xiaoliu ^a,b   Yin, Qingmei ^a   Qin, Zhanbin ^a   Yan, Xinhao ^a   Wang, Yanfei ^a   Zhang, Pingzhu ^a   Zhang, Jinchao ^a  

^a HEBEI UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Antitumor; HIV RT inhibitory; Microwave assisted; Pseudonucleosides; Staudinger aza Wittig reduction

Indexed keywords

5' ARYLAMINO 2',3' DIACETYL NUCLEOSIDE DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTINEOPLASTIC AGENT; PSEUDONUCLEOSIDE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; MICROWAVE RADIATION; REDUCTION; STAUDINGER REACTION; WITTIG REACTION;

HIV REVERSE TRANSCRIPTASE; HUMANS; MICROWAVES; NUCLEOSIDES; OXIDATION-REDUCTION; REVERSE TRANSCRIPTASE INHIBITORS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 78650509637     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.10.054     Document Type: Article

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