메뉴 건너뛰기




Volumn 21, Issue 3, 2011, Pages 302-308

A maturation model for midazolam clearance

Author keywords

allometrics; children; maturation; midazolam; pharmacokinetics

Indexed keywords

MIDAZOLAM;

EID: 78650500434     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2010.03364.x     Document Type: Article
Times cited : (72)

References (68)
  • 1
    • 40549143738 scopus 로고    scopus 로고
    • Facilitation of drug evaluation in children by population methods and modelling
    • Tod M, Jullien V, Pons G,. Facilitation of drug evaluation in children by population methods and modelling. Clin Pharmacokinet 2008; 47: 231-243. (Pubitemid 351367434)
    • (2008) Clinical Pharmacokinetics , vol.47 , Issue.4 , pp. 231-243
    • Tod, M.1    Jullien, V.2    Pons, G.3
  • 2
    • 33750344295 scopus 로고    scopus 로고
    • Population clinical pharmacology of children: Modelling covariate effects
    • DOI 10.1007/s00431-006-0189-x
    • Anderson BJ, Allegaert K, Holford NHG,. Population clinical pharmacology of children: modelling covariate effects. Eur J Pediatr 2006; 165: 819-829. (Pubitemid 44627767)
    • (2006) European Journal of Pediatrics , vol.165 , Issue.12 , pp. 819-829
    • Anderson, B.J.1    Allegaert, K.2    Holford, N.H.G.3
  • 3
    • 70049116163 scopus 로고    scopus 로고
    • Moral responsibility to attain thorough pediatric drug labeling
    • Waisel DB,. Moral responsibility to attain thorough pediatric drug labeling. Paediatr Anaesth 2009; 19: 989-993.
    • (2009) Paediatr Anaesth , vol.19 , pp. 989-993
    • Waisel, D.B.1
  • 4
    • 41749105125 scopus 로고    scopus 로고
    • The problems in scaling adult drug doses to children
    • DOI 10.1136/adc.2006.114835
    • Johnson TN,. The problems in scaling adult drug doses to children. Arch Dis Child 2008; 93: 207-211. (Pubitemid 352025489)
    • (2008) Archives of Disease in Childhood , vol.93 , Issue.3 , pp. 207-211
    • Johnson, T.N.1
  • 5
    • 33746803672 scopus 로고    scopus 로고
    • Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children
    • DOI 10.2165/00003088-200645090-00005
    • Johnson TN, Rostami-Hodjegan A, Tucker GT,. Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children. Clin Pharmacokinet 2006; 45: 931-956. (Pubitemid 44299829)
    • (2006) Clinical Pharmacokinetics , vol.45 , Issue.9 , pp. 931-956
    • Johnson, T.N.1    Rostami-Hodjegan, A.2    Tucker, G.T.3
  • 6
    • 33745599327 scopus 로고    scopus 로고
    • A mechanistic approach for the scaling of clearance in children
    • DOI 10.2165/00003088-200645070-00004
    • Edginton AN, Schmitt W, Voith B, et al. A mechanistic approach for the scaling of clearance in children. Clin Pharmacokinet 2006; 45: 683-704. (Pubitemid 43990570)
    • (2006) Clinical Pharmacokinetics , vol.45 , Issue.7 , pp. 683-704
    • Edginton, A.N.1    Schmitt, W.2    Voith, B.3    Willmann, S.4
  • 7
    • 41149180911 scopus 로고    scopus 로고
    • Mechanism-based concepts of size and maturity in pharmacokinetics
    • DOI 10.1146/annurev.pharmtox.48.113006.094708
    • Anderson BJ, Holford NH,. Mechanism-based concepts of size and maturity in pharmacokinetics. Annu Rev Pharmacol Toxicol 2008; 48: 303-332. (Pubitemid 351738156)
    • (2008) Annual Review of Pharmacology and Toxicology , vol.48 , pp. 303-332
    • Anderson, B.J.1    Holford, N.H.G.2
  • 8
    • 67649415182 scopus 로고    scopus 로고
    • Mechanistic basis of using body size and maturation to predict clearance in humans
    • Anderson BJ, Holford NH,. Mechanistic basis of using body size and maturation to predict clearance in humans. Drug Metab Pharmacokinet 2009; 24: 25-36.
    • (2009) Drug Metab Pharmacokinet , vol.24 , pp. 25-36
    • Anderson, B.J.1    Holford, N.H.2
  • 9
    • 18944386328 scopus 로고    scopus 로고
    • The origin of allometric scaling laws in biology from genomes to ecosystems: Towards a quantitative unifying theory of biological structure and organization
    • DOI 10.1242/jeb.01589
    • West GB, Brown JH,. The origin of allometric scaling laws in biology from genomes to ecosystems: towards a quantitative unifying theory of biological structure and organization. J Exp Biol 2005; 208: 1575-1592. (Pubitemid 40697606)
    • (2005) Journal of Experimental Biology , vol.208 , Issue.9 , pp. 1575-1592
    • West, G.B.1    Brown, J.H.2
  • 10
    • 0036203258 scopus 로고    scopus 로고
    • Scaling for size: Some implications for paediatric anaesthesia dosing
    • DOI 10.1046/j.1460-9592.2002.00616.x
    • Anderson BJ, Meakin GH,. Scaling for size: some implications for paediatric anaesthesia dosing. Paediatr Anaesth 2002; 12: 205-219. (Pubitemid 34264439)
    • (2002) Paediatric Anaesthesia , vol.12 , Issue.3 , pp. 205-219
    • Anderson, B.J.1    Meakin, G.H.2
  • 11
    • 0003043542 scopus 로고
    • The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves
    • Hill AV,. The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves. J Physiol 1910; 14: iv-vii.
    • (1910) J Physiol , vol.14
    • Hill, A.V.1
  • 12
    • 0035200148 scopus 로고    scopus 로고
    • The single-dose pharmacokinetics of midazolam and its primary metabolite in pediatric patients after oral and intravenous administration
    • DOI 10.1177/00912700122012832
    • Reed MD, Rodarte A, Blumer JL, et al. The single-dose pharmacokinetics of midazolam and its primary metabolite in pediatric patients after oral and intravenous administration. J Clin Pharmacol 2001; 41: 1359-1369. (Pubitemid 33104904)
    • (2001) Journal of Clinical Pharmacology , vol.41 , Issue.12 , pp. 1359-1369
    • Reed, M.D.1    Rodarte, A.2    Blumer, J.L.3    Khoo, K.-C.4    Akbari, B.5    Pou, S.6    Kearns, G.L.7
  • 13
    • 4544306610 scopus 로고    scopus 로고
    • Getting the best from pediatric pharmacokinetic data
    • DOI 10.1111/j.1460-9592.2004.01374.x
    • Anderson BJ, Hansen TG,. Getting the best from pediatric pharmacokinetic data. Paediatr Anaesth 2004; 14: 713-715. (Pubitemid 39223081)
    • (2004) Paediatric Anaesthesia , vol.14 , Issue.9 , pp. 713-715
    • Anderson, B.J.1    Hansen, T.G.2
  • 16
    • 0021273567 scopus 로고
    • The problem of choosing weights in nonlinear regression analysis of pharmacokinetic data
    • Peck CC, Sheiner LB, Nichols AI,. The problem of choosing weights in nonlinear regression analysis of pharmacokinetic data. Drug Metab Rev 1984; 15: 133-148. (Pubitemid 14123934)
    • (1984) Drug Metabolism Reviews , vol.15 , Issue.1-2 , pp. 133-148
    • Peck, C.C.1    Sheiner, L.B.2    Nichols, A.I.3
  • 17
    • 0021735934 scopus 로고
    • Extended least squares nonlinear regression: A possible solution to the "choice of weights" problem in analysis of individual pharmacokinetic parameters
    • Peck CC, Beal SL, Sheiner LB, et al. Extended least squares nonlinear regression: a possible solution to the "choice of weights" problem in analysis of individual pharmacokinetic parameters. J Pharmacokinet Biopharm 1984; 12: 545-557.
    • (1984) J Pharmacokinet Biopharm , vol.12 , pp. 545-557
    • Peck, C.C.1    Beal, S.L.2    Sheiner, L.B.3
  • 18
    • 20644465189 scopus 로고    scopus 로고
    • Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: Theophylline and midazolam as model drugs
    • Bjorkman S., Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs. Br J Clin Pharmacol 59: 691-704.
    • Br J Clin Pharmacol , vol.59 , pp. 691-704
    • Bjorkman, S.1
  • 19
    • 84908219488 scopus 로고
    • Statistical methods for assessing agreement between two methods of clinical measurement
    • PII S0140673686908378
    • Bland JM, Altman DG,. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1: 307-310. (Pubitemid 16134762)
    • (1986) Lancet , vol.1 , Issue.8476 , pp. 307-310
    • Bland, J.M.1    Altman, D.G.2
  • 20
    • 20644445856 scopus 로고    scopus 로고
    • Modelling approaches to dose estimation in children
    • DOI 10.1111/j.1365-2125.2005.02429.x
    • Johnson TN,. Modelling approaches to dose estimation in children. Br J Clin Pharmacol 2005; 59: 663-669. (Pubitemid 40835498)
    • (2005) British Journal of Clinical Pharmacology , vol.59 , Issue.6 , pp. 663-669
    • Johnson, T.N.1
  • 22
    • 0141791117 scopus 로고    scopus 로고
    • The development of drug metabolising enzymes and their influence on the susceptibility to adverse drug reactions in children
    • DOI 10.1016/S0300-483X(03)00249-X
    • Johnson TN,. The development of drug metabolising enzymes and their influence on the susceptibility to adverse drug reactions in children. Toxicology 2003; 192: 37-48. (Pubitemid 37153342)
    • (2003) Toxicology , vol.192 , Issue.1 , pp. 37-48
    • Johnson, T.N.1
  • 24
    • 0036156595 scopus 로고    scopus 로고
    • The ontogeny of human drug-metabolizing enzymes: Phase I oxidative enzymes
    • DOI 10.1124/jpet.300.2.355
    • Hines RN, McCarver DG,. The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes. J Pharmacol Exp Ther 2002; 300: 355-360. (Pubitemid 34106223)
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.300 , Issue.2 , pp. 355-360
    • Hines, R.N.1    McCarver, D.G.2
  • 25
    • 0030750270 scopus 로고    scopus 로고
    • Expression of CYP3A in the human liver - Evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth
    • Lacroix D, Sonnier M, Moncion A, et al. Expression of CYP3A in the human liver-evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth. Eur J Biochem 1997; 247: 625-634. (Pubitemid 27308642)
    • (1997) European Journal of Biochemistry , vol.247 , Issue.2 , pp. 625-634
    • Lacroix, D.1    Sonnier, M.2    Moncion, A.3    Cheron, G.4    Cresteil, T.5
  • 26
    • 37549039830 scopus 로고    scopus 로고
    • Paradoxical effects of midazolam in the very young
    • Tobin JR,. Paradoxical effects of midazolam in the very young. Anesthesiology 2008; 108: 6-7.
    • (2008) Anesthesiology , vol.108 , pp. 6-7
    • Tobin, J.R.1
  • 29
    • 0022620570 scopus 로고
    • Midazolam-fentanyl anesthesia for major surgery. Plasma levels of midazolam during prolonged total intravenous anesthesia
    • Nilsson A, Tamsen A, Persson P,. Midazolam-fentanyl anesthesia for major surgery. Plasma levels of midazolam during prolonged total intravenous anesthesia. Acta Anaesthesiol Scand 1986; 30: 66-69. (Pubitemid 16155895)
    • (1986) Acta Anaesthesiologica Scandinavica , vol.30 , Issue.1 , pp. 66-69
    • Nilsson, A.1    Tamsen, A.2    Persson, P.3
  • 31
    • 0026611310 scopus 로고
    • Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers
    • Mandema JW, Tuk B, van Steveninck AL, et al. Pharmacokinetic- pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers. Clin Pharmacol Ther 1992; 51: 715-728.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 715-728
    • Mandema, J.W.1    Tuk, B.2    Van Steveninck, A.L.3
  • 33
    • 0025204233 scopus 로고
    • Electroencephalographic effects of benzodiazepines. II. Pharmacodynamic modeling of the electroencephalographic effects of midazolam and diazepam
    • Buhrer M, Maitre PO, Crevoisier C, et al. Electroencephalographic effects of benzodiazepines. II. Pharmacodynamic modeling of the electroencephalographic effects of midazolam and diazepam. Clin Pharmacol Ther 1990; 48: 555-567.
    • (1990) Clin Pharmacol Ther , vol.48 , pp. 555-567
    • Buhrer, M.1    Maitre, P.O.2    Crevoisier, C.3
  • 34
    • 0036041107 scopus 로고    scopus 로고
    • Contribution of midazolam and its 1-hydroxy metabolite to preoperative sedation in children: A pharmacokinetic-pharmacodynamic analysis
    • DOI 10.1093/bja/aef213
    • Johnson TN, Rostami-Hodjegan A, Goddard JM, et al. Contribution of midazolam and its 1-hydroxy metabolite to preoperative sedation in children: a pharmacokinetic-pharmacodynamic analysis. Br J Anaesth 2002; 89: 428-437. (Pubitemid 34993972)
    • (2002) British Journal of Anaesthesia , vol.89 , Issue.3 , pp. 428-437
    • Johnson, T.N.1    Rostami-Hodjegan, A.2    Goddard, J.M.3    Tanner, M.S.4    Tucker, G.T.5
  • 36
    • 0031972078 scopus 로고    scopus 로고
    • Clearance of morphine in postoperative infants during intravenous infusion: The influence of age and surgery
    • DOI 10.1097/00000539-199805000-00008
    • Lynn A, Nespeca MK, Bratton SL, et al. Clearance of morphine in postoperative infants during intravenous infusion: the influence of age and surgery. Anesth Analg 1998; 86: 958-963. (Pubitemid 28198858)
    • (1998) Anesthesia and Analgesia , vol.86 , Issue.5 , pp. 958-963
    • Lynn, A.1    Nespeca, M.K.2    Bratton, S.L.3    Strauss, S.G.4    Shen, D.D.5
  • 37
    • 14944358508 scopus 로고    scopus 로고
    • Morphine pharmacokinetics during venoarterial extracorporeal membrane oxygenation in neonates
    • DOI 10.1007/s00134-004-2545-5
    • Peters JW, Anderson BJ, Simons SH, et al. Morphine pharmacokinetics during venoarterial extracorporeal membrane oxygenation in neonates. Intensive Care Med 2005; 31: 257-263. (Pubitemid 40362275)
    • (2005) Intensive Care Medicine , vol.31 , Issue.2 , pp. 257-263
    • Peters, J.W.B.1    Anderson, B.J.2    Simons, S.H.P.3    Uges, D.R.A.4    Tibboel, D.5
  • 38
    • 0023814481 scopus 로고
    • A pharmacokinetic study of midazolam in paediatric patients undergoing cardiac surgery
    • Mathews HM, Carson IW, Lyons SM, et al. A pharmacokinetic study of midazolam in paediatric patients undergoing cardiac surgery. Br J Anaesth 1988; 61: 302-307.
    • (1988) Br J Anaesth , vol.61 , pp. 302-307
    • Mathews, H.M.1    Carson, I.W.2    Lyons, S.M.3
  • 39
    • 0022522087 scopus 로고
    • Sedation of children requiring artificial ventilation using an infusion of midazolam
    • Booker PD, Beechey A, Lloyd-Thomas AR,. Sedation of children requiring artificial ventilation using an infusion of midazolam. Br J Anaesth 1986; 58: 1104-1108. (Pubitemid 16031585)
    • (1986) British Journal of Anaesthesia , vol.58 , Issue.10 , pp. 1104-1108
    • Booker, P.D.1    Beechey, A.2    Lloyd-Thomas, A.R.3
  • 40
    • 0025681705 scopus 로고
    • Unconsciousness associated with midazolam and erythromycin
    • Hiller A, Olkkola KT, Isohanni P, et al. Unconsciousness associated with midazolam and erythromycin. Br J Anaesth 1990; 65: 826-828.
    • (1990) Br J Anaesth , vol.65 , pp. 826-828
    • Hiller, A.1    Olkkola, K.T.2    Isohanni, P.3
  • 43
    • 76949088683 scopus 로고    scopus 로고
    • Ontogeny of midazolam glucuronidation in preterm infants
    • de Wildt SN, Kearns GL, Murry DJ, et al. Ontogeny of midazolam glucuronidation in preterm infants. Eur J Clin Pharmacol 2010; 66: 165-170.
    • (2010) Eur J Clin Pharmacol , vol.66 , pp. 165-170
    • De Wildt, S.N.1    Kearns, G.L.2    Murry, D.J.3
  • 44
    • 0031875719 scopus 로고    scopus 로고
    • Clinical pharmacology of midazolam in infants and children
    • DOI 10.2165/00003088-199835010-00003
    • Blumer J,. Clinical pharmacology of midazolam in infants and children. Clin Pharmacokinet 1998; 35: 37-47. (Pubitemid 28318961)
    • (1998) Clinical Pharmacokinetics , vol.35 , Issue.1 , pp. 37-47
    • Blumer, J.L.1
  • 45
    • 59849122627 scopus 로고    scopus 로고
    • Human renal function maturation: A quantitative description using weight and postmenstrual age
    • Rhodin MM, Anderson BJ, Peters AM, et al. Human renal function maturation: a quantitative description using weight and postmenstrual age. Pediatr Nephrol 2009; 24: 67-76.
    • (2009) Pediatr Nephrol , vol.24 , pp. 67-76
    • Rhodin, M.M.1    Anderson, B.J.2    Peters, A.M.3
  • 47
    • 57749186454 scopus 로고    scopus 로고
    • Population pharmacokinetics of sildenafil in term neonates: Evidence of rapid maturation of metabolic clearance in the early postnatal period
    • Mukherjee A, Dombi T, Wittke B, et al. Population pharmacokinetics of sildenafil in term neonates: evidence of rapid maturation of metabolic clearance in the early postnatal period. Clin Pharmacol Ther 2009; 85: 56-63.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 56-63
    • Mukherjee, A.1    Dombi, T.2    Wittke, B.3
  • 48
    • 33645299020 scopus 로고    scopus 로고
    • Age and size are the major covariates for prediction of levobupivacaine clearance in children
    • Chalkiadis GA, Anderson BJ,. Age and size are the major covariates for prediction of levobupivacaine clearance in children. Pediatr Anesth 2006; 16: 275-282.
    • (2006) Pediatr Anesth , vol.16 , pp. 275-282
    • Chalkiadis, G.A.1    Anderson, B.J.2
  • 50
    • 70049107996 scopus 로고    scopus 로고
    • Data sharing for pharmacokinetic studies
    • Anderson BJ, Merry AF,. Data sharing for pharmacokinetic studies. Paediatr Anaesth 2009; 19: 1005-1010.
    • (2009) Paediatr Anaesth , vol.19 , pp. 1005-1010
    • Anderson, B.J.1    Merry, A.F.2
  • 51
    • 0032935544 scopus 로고    scopus 로고
    • Population pharmacokinetic modeling in very premature infants receiving midazolam during mechanical ventilation: Midazolam neonatal pharmacokinetics
    • DOI 10.1097/00000542-199902000-00020
    • Lee TC, Charles BG, Harte GJ, et al. Population pharmacokinetic modeling in very premature infants receiving midazolam during mechanical ventilation: midazolam neonatal pharmacokinetics. Anesthesiology 1999; 90: 451-457. (Pubitemid 29071514)
    • (1999) Anesthesiology , vol.90 , Issue.2 , pp. 451-457
    • Lee, T.C.1    Charles, B.G.2    Harte, G.J.3    Gray, P.H.4    Steer, P.A.5    Flenady, V.J.6
  • 52
    • 0030783008 scopus 로고    scopus 로고
    • Haemodynamic responses and population pharmacokinetics of midazolam following administration to ventilated, preterm neonates
    • Harte GJ, Gray PH, Lee TC, et al. Haemodynamic responses and population pharmacokinetics of midazolam following administration to ventilated, preterm neonates. J Paediatr Child Health 1997; 33: 335-338. (Pubitemid 27396189)
    • (1997) Journal of Paediatrics and Child Health , vol.33 , Issue.4 , pp. 335-338
    • Harte, G.J.1    Gray, P.H.2    Lee, T.C.3    Steer, P.A.4    Charles, B.G.5
  • 54
    • 0026580096 scopus 로고
    • Pharmacokinetics of midazolam during continuous infusion in critically ill neonates
    • Jacqz-Aigrain E, Daoud P, Burtin P, et al. Pharmacokinetics of midazolam during continuous infusion in critically ill neonates. Eur J Clin Pharmacol 1992; 42: 329-332.
    • (1992) Eur J Clin Pharmacol , vol.42 , pp. 329-332
    • Jacqz-Aigrain, E.1    Daoud, P.2    Burtin, P.3
  • 56
    • 0042344946 scopus 로고    scopus 로고
    • Pharmacokinetics of midazolam in neonates undergoing extracorporeal membrane oxygenation
    • DOI 10.1097/00000542-200308000-00008
    • Mulla H, McCormack P, Lawson G, et al. Pharmacokinetics of midazolam in neonates undergoing extracorporeal membrane oxygenation. Anesthesiology 2003; 99: 275-282. (Pubitemid 36909552)
    • (2003) Anesthesiology , vol.99 , Issue.2 , pp. 275-282
    • Mulla, H.1    McCormack, P.2    Lawson, G.3    Firmin, R.K.4    Upton, D.R.5
  • 57
    • 51649114041 scopus 로고    scopus 로고
    • Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions
    • Muchohi SN, Kokwaro GO, Ogutu BR, et al. Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions. Br J Clin Pharmacol 2008; 66: 529-538.
    • (2008) Br J Clin Pharmacol , vol.66 , pp. 529-538
    • Muchohi, S.N.1    Kokwaro, G.O.2    Ogutu, B.R.3
  • 58
    • 0026048409 scopus 로고
    • Pharmacokinetics of midazolam in children: Comparative study of intranasal and intravenous administration
    • Rey E, Delaunay L, Pons G, et al. Pharmacokinetics of midazolam in children: comparative study of intranasal and intravenous administration. Eur J Clin Pharmacol 1991; 41: 355-357.
    • (1991) Eur J Clin Pharmacol , vol.41 , pp. 355-357
    • Rey, E.1    Delaunay, L.2    Pons, G.3
  • 60
    • 0023255951 scopus 로고
    • Midazolam as an induction agent in children: A pharmacokinetic and clinical study
    • Salonen M, Kanto J, Iisalo E, et al. Midazolam as an induction agent in children: a pharmacokinetic and clinical study. Anesth Analg 1987; 66: 625-628. (Pubitemid 17113612)
    • (1987) Anesthesia and Analgesia , vol.66 , Issue.7 , pp. 625-628
    • Salonen, M.1    Kanto, J.2    Iisalo, E.3    Himberg, J.-J.4
  • 61
    • 0025913776 scopus 로고
    • Pharmacokinetic and pharmacodynamic study of midazolam in children during esophagogastroduodenoscopy
    • Tolia V, Brennan S, Aravind MK, et al. Pharmacokinetic and pharmacodynamic study of midazolam in children during esophagogastroduodenoscopy. J Pediatr 1991; 119: 467-471.
    • (1991) J Pediatr , vol.119 , pp. 467-471
    • Tolia, V.1    Brennan, S.2    Aravind, M.K.3
  • 62
    • 0030025176 scopus 로고    scopus 로고
    • Steady-state plasma concentrations of midazolam in critically ill infants and children
    • Hughes J, Gill AM, Mulhearn H, et al. Steady-state plasma concentrations of midazolam in critically ill infants and children. Ann Pharmacother 1996; 30: 27-30. (Pubitemid 26025415)
    • (1996) Annals of Pharmacotherapy , vol.30 , Issue.1 , pp. 27-30
    • Hughes, J.1    Gill, A.M.2    Mulhearn, H.3    Powell, E.4    Choonara, I.5
  • 63
    • 0023917533 scopus 로고
    • Pharmacokinetics of midazolam and alpha-hydroxy-midazolam following rectal and intravenous administration
    • Clausen TG, Wolff J, Hansen PB, et al. Pharmacokinetics of midazolam and alpha-hydroxy-midazolam following rectal and intravenous administration. Br J Clin Pharmacol 1988; 25: 457-463.
    • (1988) Br J Clin Pharmacol , vol.25 , pp. 457-463
    • Clausen, T.G.1    Wolff, J.2    Hansen, P.B.3
  • 64
    • 0024509738 scopus 로고
    • Pharmacokinetics of midazolam following intravenous and oral administration in patients with chronic liver disease and in healthy subjects
    • Pentikainen PJ, Valisalmi L, Himberg JJ, et al. Pharmacokinetics of midazolam following intravenous and oral administration in patients with chronic liver disease and in healthy subjects. J Clin Pharmacol 1989; 29: 272-277. (Pubitemid 19087927)
    • (1989) Journal of Clinical Pharmacology , vol.29 , Issue.3 , pp. 272-277
    • Pentikainen, P.J.1    Valisalmi, L.2    Himberg, J.-J.3    Crevoisier, C.4
  • 66
    • 0034820636 scopus 로고    scopus 로고
    • Prediction of the disposition of midazolam in surgical patients by a physiologically based pharmacokinetic model
    • DOI 10.1002/jps.1076
    • Bjorkman S, Wada DR, Berling BM,. Prediction of the disposition of midazolam in surgical patients by a physiologically based pharmacokinetic model. J Pharm Sci 2001; 90: 1226-1241. (Pubitemid 32867972)
    • (2001) Journal of Pharmaceutical Sciences , vol.90 , Issue.9 , pp. 1226-1241
    • Bjorkman, S.1    Wada, D.R.2    Berling, B.-M.3    Benoni, G.4
  • 67
    • 0021192084 scopus 로고
    • Effect of age, gender, and obesity on midazolam kinetics
    • Greenblatt DJ, Abernethy DR, Locniskar A, et al. Effect of age, gender, and obesity on midazolam kinetics. Anesthesiology 1984; 61: 27-35. (Pubitemid 14089351)
    • (1984) Anesthesiology , vol.61 , Issue.1 , pp. 27-35
    • Greenblatt, D.J.1    Abernethy, D.R.2    Locniskar, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.