The single-dose pharmacokinetics of midazolam and its primary metabolite in pediatric patients after oral and intravenous administration

Journal of Clinical Pharmacology

Volumn 41, Issue 12, 2001, Pages 1359-1369

  Reed, Michael D ^a   Rodarte, Alexander ^b   Blumer, Jeffrey L ^a   Khoo, Ko Chin ^c   Akbari, Bardia ^c   Pou, Sovitj ^d   Kearns, Gregory L ^e  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b RADY CHILDREN'S HOSPITAL   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

^d ICON Development Solutions   (United States)

^e CHILDREN S MERCY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA HYDROXYMIDAZOLAM; DRUG METABOLITE; MIDAZOLAM;

ADOLESCENT; AREA UNDER THE CURVE; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISTRIBUTION VOLUME; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG METABOLISM; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; SEDATION; SYRUP;

ADMINISTRATION, ORAL; ADOLESCENT; AGING; ANTI-ANXIETY AGENTS; AREA UNDER CURVE; BIOTRANSFORMATION; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INJECTIONS, INTRAVENOUS; MALE; MIDAZOLAM; POPULATION; PROSPECTIVE STUDIES;

EID: 0035200148     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/00912700122012832     Document Type: Article

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