메뉴 건너뛰기




Volumn 100, Issue 1, 2011, Pages 112-121

Developing pathogen reduction technologies for RBC suspensions

Author keywords

Component storage; Pathogen reduction; Red cell; Transfusion; Transmissible infections

Indexed keywords

ALKYLATING AGENT; BENZOPORPHYRIN DERIVATIVE; HYPERICIN; INACTINE; MEROCYANINE; PHOTOSENSITIZING AGENT; PHTHALOCYANINE; S 303; THIAZOLE ORANGE; THIOPYRYLIUM; UNCLASSIFIED DRUG;

EID: 78650395330     PISSN: 00429007     EISSN: 14230410     Source Type: Journal    
DOI: 10.1111/j.1423-0410.2010.01386.x     Document Type: Review
Times cited : (11)

References (57)
  • 1
    • 34848872294 scopus 로고    scopus 로고
    • Current risk for transfusion transmitted infections
    • Dodd RY: Current risk for transfusion transmitted infections. Curr Opin Hematol 2007; 14:671-676
    • (2007) Curr Opin Hematol , vol.14 , pp. 671-676
    • Dodd, R.Y.1
  • 2
    • 68149125565 scopus 로고    scopus 로고
    • Emerging infectious disease agents and their potential threat to transfusion safety
    • Stramer SL, Hollinger FB, Katz LM, et al. Emerging infectious disease agents and their potential threat to transfusion safety. Transfusion 2009; 49(Suppl 2):1S-29S
    • (2009) Transfusion , vol.49 , Issue.SUPPL. 2
    • Stramer, S.L.1    Hollinger, F.B.2    Katz, L.M.3
  • 4
    • 34248145455 scopus 로고    scopus 로고
    • Pathogen inactivation. The definitive safeguard for the blood supply
    • Bryant BJ, Klein HG: Pathogen inactivation. The definitive safeguard for the blood supply. Arch Pathol Lab Med 2007; 131:719-733
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 719-733
    • Bryant, B.J.1    Klein, H.G.2
  • 5
    • 47349090837 scopus 로고    scopus 로고
    • Pathogen reduction of blood components
    • Solheim BG: Pathogen reduction of blood components. Transfus Apher Sci 2008; 39:75-82
    • (2008) Transfus Apher Sci , vol.39 , pp. 75-82
    • Solheim, B.G.1
  • 6
    • 0025717470 scopus 로고
    • Approaches to the reduction of viral infectivity in cellular blood components and single donor plasma
    • Wagner SJ, Friedman LI, Dodd RY: Approaches to the reduction of viral infectivity in cellular blood components and single donor plasma. Transfus Med Rev 1991; 1:18-32
    • (1991) Transfus Med Rev , vol.1 , pp. 18-32
    • Wagner, S.J.1    Friedman, L.I.2    Dodd, R.Y.3
  • 7
    • 77955127865 scopus 로고    scopus 로고
    • Defining "adequate" pathogen reduction performance for transfused blood components
    • doi.
    • Goodrich RP, Custer B, Keil S, et al. Defining "adequate" pathogen reduction performance for transfused blood components. Transfusion 2010: doi.
    • (2010) Transfusion
    • Goodrich, R.P.1    Custer, B.2    Keil, S.3
  • 8
    • 0035686474 scopus 로고    scopus 로고
    • High-titer screening PCR: a successful strategy for reducing the parvovirus B19 load in plasma pools for fractionation
    • Weimer T, Streichert S, Watson C, et al. High-titer screening PCR: a successful strategy for reducing the parvovirus B19 load in plasma pools for fractionation. Transfusion 2001; 41:1500-1504
    • (2001) Transfusion , vol.41 , pp. 1500-1504
    • Weimer, T.1    Streichert, S.2    Watson, C.3
  • 9
    • 68149131080 scopus 로고    scopus 로고
    • Limiting and detecting bacterial contamination of apheresis platelets: inlet-line diversion and increased culture volume improve component safety
    • Eder AF, Kennedy JM, Dy BA, et al. Limiting and detecting bacterial contamination of apheresis platelets: inlet-line diversion and increased culture volume improve component safety. Transfusion 2009; 49:1554-1563
    • (2009) Transfusion , vol.49 , pp. 1554-1563
    • Eder, A.F.1    Kennedy, J.M.2    Dy, B.A.3
  • 10
    • 0025928204 scopus 로고
    • Quenching of singlet oxygen by human RBC ghosts
    • Kanofsky JR: Quenching of singlet oxygen by human RBC ghosts. Photochem Photobiol 1991; 53:93-99
    • (1991) Photochem Photobiol , vol.53 , pp. 93-99
    • Kanofsky, J.R.1
  • 11
    • 33750681660 scopus 로고    scopus 로고
    • Spatially resolved cellular responses to singlet oxygen
    • Redmond RW, Kochevar IE: Spatially resolved cellular responses to singlet oxygen. Photochem Photobiol 2006; 82:1178-1186
    • (2006) Photochem Photobiol , vol.82 , pp. 1178-1186
    • Redmond, R.W.1    Kochevar, I.E.2
  • 12
    • 0026734552 scopus 로고
    • Merocyanine 540-sensitized photoinactivation of enveloped viruses in blood products: site and mechanism of phototoxicity
    • O'Brien JM, Gaffney DK, Wang TP, et al. Merocyanine 540-sensitized photoinactivation of enveloped viruses in blood products: site and mechanism of phototoxicity. Blood 1992; 80:277-285
    • (1992) Blood , vol.80 , pp. 277-285
    • O'Brien, J.M.1    Gaffney, D.K.2    Wang, T.P.3
  • 13
    • 84995135769 scopus 로고
    • Photochemical inactivation of virus in RBCs
    • (abstract S145)
    • Cole M, Stromberg RR, Friedman LI, et al. Photochemical inactivation of virus in RBCs. Transfusion 1989; 29:42S (abstract S145)
    • (1989) Transfusion , vol.29
    • Cole, M.1    Stromberg, R.R.2    Friedman, L.I.3
  • 14
    • 0026606492 scopus 로고
    • Antiviral effects of photosensitizing merocyanine dyes: implications for transfusion and bone marrow transplantation
    • Sieber F, O'Brien JM, Gaffney DK: Antiviral effects of photosensitizing merocyanine dyes: implications for transfusion and bone marrow transplantation. Semin Hematol 1992; 29:79-87
    • (1992) Semin Hematol , vol.29 , pp. 79-87
    • Sieber, F.1    O'Brien, J.M.2    Gaffney, D.K.3
  • 15
    • 0026512145 scopus 로고
    • Viral inactivation in blood and RBC concentrates with benzoporphyrin derivative
    • North J, Neyndorff H, King D, et al. Viral inactivation in blood and RBC concentrates with benzoporphyrin derivative. Blood Cells 1992; 18:129-140
    • (1992) Blood Cells , vol.18 , pp. 129-140
    • North, J.1    Neyndorff, H.2    King, D.3
  • 16
    • 0031104656 scopus 로고    scopus 로고
    • The effect of disinfection on viability and function of baboon red blood cells
    • Valeri CR, Ragno G, MacGregor H, et al. The effect of disinfection on viability and function of baboon red blood cells. Photochem Photobiol 1997; 65:446-450
    • (1997) Photochem Photobiol , vol.65 , pp. 446-450
    • Valeri, C.R.1    Ragno, G.2    MacGregor, H.3
  • 17
    • 0034143198 scopus 로고    scopus 로고
    • Strategies for evaluation of enveloped virus inactivation in RBC concentrates using hypericin
    • Prince AM, Pascual D, Meruelo D, et al. Strategies for evaluation of enveloped virus inactivation in RBC concentrates using hypericin. Photochem Photobiol 2000; 71:188-195
    • (2000) Photochem Photobiol , vol.71 , pp. 188-195
    • Prince, A.M.1    Pascual, D.2    Meruelo, D.3
  • 18
    • 0025976794 scopus 로고
    • Inactivation of viruses in blood with aluminum phthalocyanine derivatives
    • Howorowitz B, Williams B, Rywkin S, et al. Inactivation of viruses in blood with aluminum phthalocyanine derivatives. Transfusion 1991; 31:102-108
    • (1991) Transfusion , vol.31 , pp. 102-108
    • Howorowitz, B.1    Williams, B.2    Rywkin, S.3
  • 19
    • 0028997092 scopus 로고
    • Virus inactivation in RBC concentrates by photosensitization with phthalocyanines: protection of RBCs by not of vesicular stomatitis virus with a water-soluble analogue of vitamin E
    • Ben-Hur E, Rywkin S, Rosenthal I, et al. Virus inactivation in RBC concentrates by photosensitization with phthalocyanines: protection of RBCs by not of vesicular stomatitis virus with a water-soluble analogue of vitamin E. Transfusion 1995; 35:401-406
    • (1995) Transfusion , vol.35 , pp. 401-406
    • Ben-Hur, E.1    Rywkin, S.2    Rosenthal, I.3
  • 20
    • 0029024099 scopus 로고
    • Selective protection against IgG binding to RBCs treated with phthalocyanines and red light for virus inactivation
    • Rywkin S, Ben-Hur E, Reid ME, et al. Selective protection against IgG binding to RBCs treated with phthalocyanines and red light for virus inactivation. Transfusion 1995; 35:414-420
    • (1995) Transfusion , vol.35 , pp. 414-420
    • Rywkin, S.1    Ben-Hur, E.2    Reid, M.E.3
  • 21
    • 0033642456 scopus 로고    scopus 로고
    • Photochemical decontamination of red blood cell concentrates with the silicon phthalocyanine PC4 and red light
    • Ben-Hur E, Chan WS, Yim Z, et al. Photochemical decontamination of red blood cell concentrates with the silicon phthalocyanine PC4 and red light. Dev Biol (Basel) 2000; 102:149-156
    • (2000) Dev Biol (Basel) , vol.102 , pp. 149-156
    • Ben-Hur, E.1    Chan, W.S.2    Yim, Z.3
  • 22
    • 0027446373 scopus 로고
    • RBC membrane alterations associated with virucidal methylene blue phototreatment
    • Wagner SJ, Storry JR, Mallory DA, et al. RBC membrane alterations associated with virucidal methylene blue phototreatment. Transfusion 1992; 33:30-36
    • (1992) Transfusion , vol.33 , pp. 30-36
    • Wagner, S.J.1    Storry, J.R.2    Mallory, D.A.3
  • 23
    • 0028245124 scopus 로고
    • Differential sensitivity of viruses in RBCs to methylene blue photosensitization
    • Wagner SJ, Robinette D, Storry J, et al. Differential sensitivity of viruses in RBCs to methylene blue photosensitization. Transfusion 1994; 34:521-526
    • (1994) Transfusion , vol.34 , pp. 521-526
    • Wagner, S.J.1    Robinette, D.2    Storry, J.3
  • 24
    • 0031105373 scopus 로고    scopus 로고
    • Comparison of methylene blue and methylene violet for photoinactivation of intracellular and extracellular virus in RBC suspensions
    • Skripchenko A, Robinette D, Wagner SJ: Comparison of methylene blue and methylene violet for photoinactivation of intracellular and extracellular virus in RBC suspensions. Photochem Photobiol 1997; 65:451-455
    • (1997) Photochem Photobiol , vol.65 , pp. 451-455
    • Skripchenko, A.1    Robinette, D.2    Wagner, S.J.3
  • 25
    • 0031853826 scopus 로고    scopus 로고
    • Preservation of RBC properties after virucidal phototreatment with dimethylmethylene blue
    • Wagner SJ, Skripchenko A, Robinette D, et al. Preservation of RBC properties after virucidal phototreatment with dimethylmethylene blue. Transfusion 1998; 38:729-737
    • (1998) Transfusion , vol.38 , pp. 729-737
    • Wagner, S.J.1    Skripchenko, A.2    Robinette, D.3
  • 26
    • 0036725430 scopus 로고    scopus 로고
    • Use of a flow-cell system to investigate virucidal dimethylmethylene blue phototreatment in two RBC additive solutions
    • Wagner S, Skripchenko A, Thompson-Montgomery D: Use of a flow-cell system to investigate virucidal dimethylmethylene blue phototreatment in two RBC additive solutions. Transfusion 2002; 42:1200-1205
    • (2002) Transfusion , vol.42 , pp. 1200-1205
    • Wagner, S.1    Skripchenko, A.2    Thompson-Montgomery, D.3
  • 27
    • 0036878757 scopus 로고    scopus 로고
    • Quinacrine enhances vesicular stomatitis virus inactivation and diminishes hemolysis of dimethylmethylene blue phototreated cells
    • Wagner SJ, Skripchenko A, Thompson-Montgomery D: Quinacrine enhances vesicular stomatitis virus inactivation and diminishes hemolysis of dimethylmethylene blue phototreated cells. Photochem Photobiol 2002; 76:514-517
    • (2002) Photochem Photobiol , vol.76 , pp. 514-517
    • Wagner, S.J.1    Skripchenko, A.2    Thompson-Montgomery, D.3
  • 28
    • 0036595847 scopus 로고    scopus 로고
    • The band III ligand dipyridamole protects human RBCs during photodynamic treatment while extracellular virus inactivation is not affected
    • Besselink GAJ, van Engelenburg FAC, Korsten HG, et al. The band III ligand dipyridamole protects human RBCs during photodynamic treatment while extracellular virus inactivation is not affected. Transfusion 2002; 42:728-733
    • (2002) Transfusion , vol.42 , pp. 728-733
    • Besselink, G.A.J.1    van Engelenburg, F.A.C.2    Korsten, H.G.3
  • 29
    • 34548287402 scopus 로고    scopus 로고
    • "Switched-on" flexible chalcogenopyrylium photosensitizers. changes in photophysical properties upon binding to DNA
    • Ohulchanskyy TY, Gannon MK II, Ye M, et al. "Switched-on" flexible chalcogenopyrylium photosensitizers. changes in photophysical properties upon binding to DNA. J Phys Chem B 2007; 111:9686-9692
    • (2007) J Phys Chem B , vol.111 , pp. 9686-9692
    • Ohulchanskyy, T.Y.1    Gannon II, M.K.2    Ye, M.3
  • 30
    • 18544368131 scopus 로고    scopus 로고
    • Use of a flexible thiopyrylium photosensitizer and competitive inhibitor for pathogen reduction of viruses and bacteria with retention of RBC storage properties
    • Wagner SJ, Skripchenko A, Cincotta L, et al. Use of a flexible thiopyrylium photosensitizer and competitive inhibitor for pathogen reduction of viruses and bacteria with retention of RBC storage properties. Transfusion 2005; 45:752-760
    • (2005) Transfusion , vol.45 , pp. 752-760
    • Wagner, S.J.1    Skripchenko, A.2    Cincotta, L.3
  • 31
    • 33746441033 scopus 로고    scopus 로고
    • Photoinactivation of Leishmania donovani infantum in RBC suspensions by a flexible thiopyrylium sensitizer
    • Wagner SJ, Skripchenko A, Salata J, et al. Photoinactivation of Leishmania donovani infantum in RBC suspensions by a flexible thiopyrylium sensitizer. Vox Sang 2006; 91:178-180
    • (2006) Vox Sang , vol.91 , pp. 178-180
    • Wagner, S.J.1    Skripchenko, A.2    Salata, J.3
  • 32
    • 35348911927 scopus 로고    scopus 로고
    • Photoinactivation of Trypanosoma cruzi in RBC suspensions with thiopyrylium
    • Wagner SJ, Skripchenko A, Salata J, et al. Photoinactivation of Trypanosoma cruzi in RBC suspensions with thiopyrylium. Transfus Apher Sci 2007; 37:23-25
    • (2007) Transfus Apher Sci , vol.37 , pp. 23-25
    • Wagner, S.J.1    Skripchenko, A.2    Salata, J.3
  • 33
    • 33846933033 scopus 로고    scopus 로고
    • In vivo recovery and survival of RBCs after photodynamic treatment with thiopyrylium and red light using a canine model
    • Skripchenko A, Balch A, Mackin A, et al. In vivo recovery and survival of RBCs after photodynamic treatment with thiopyrylium and red light using a canine model. Vox Sang 2007; 92:157-159
    • (2007) Vox Sang , vol.92 , pp. 157-159
    • Skripchenko, A.1    Balch, A.2    Mackin, A.3
  • 34
    • 0029874851 scopus 로고    scopus 로고
    • Single- and double-strand photocleavage of DNA by YO, YOYO and TOTO
    • Akerman B, Tuite E: Single- and double-strand photocleavage of DNA by YO, YOYO and TOTO. Nucleic Acids Res 1996; 24:1080-1090
    • (1996) Nucleic Acids Res , vol.24 , pp. 1080-1090
    • Akerman, B.1    Tuite, E.2
  • 35
    • 33644848731 scopus 로고    scopus 로고
    • Thiazole orange, a DNA-binding photosensitizer with flexible structure, can inactivate pathogens in red blood cell suspensions while maintaining RBC storage properties
    • Skripchenko A, Wagner SJ, Thompson-Montgomery D, et al. Thiazole orange, a DNA-binding photosensitizer with flexible structure, can inactivate pathogens in red blood cell suspensions while maintaining RBC storage properties. Transfusion 2006; 46:213-219
    • (2006) Transfusion , vol.46 , pp. 213-219
    • Skripchenko, A.1    Wagner, S.J.2    Thompson-Montgomery, D.3
  • 36
    • 52049103376 scopus 로고    scopus 로고
    • Inactivation of Leishmania donovani infantum and Trypanosoma cruzi in RBC suspensions with thiazole orange
    • Wagner SJ, Skripchenko A, Salata J, et al. Inactivation of Leishmania donovani infantum and Trypanosoma cruzi in RBC suspensions with thiazole orange. Transfusion 2008; 48:1363-1367
    • (2008) Transfusion , vol.48 , pp. 1363-1367
    • Wagner, S.J.1    Skripchenko, A.2    Salata, J.3
  • 37
    • 0023988186 scopus 로고
    • Characteristics of the mutagenic and toxic effects of ethylene imine and its oligomers. Comparative study in the automated SOS-chromotest system and in standard bacterial test systems
    • Tanirbergenov TB, Vasil'eva SV, Kostianovskii RG, et al. Characteristics of the mutagenic and toxic effects of ethylene imine and its oligomers. Comparative study in the automated SOS-chromotest system and in standard bacterial test systems. Genetika 1988; 24:763-765
    • (1988) Genetika , vol.24 , pp. 763-765
    • Tanirbergenov, T.B.1    Vasil'eva, S.V.2    Kostianovskii, R.G.3
  • 38
    • 0036480485 scopus 로고    scopus 로고
    • Process for the preparation of pathogen-inactivated RBC concentrates by using PEN 110 chemistry: preclinical studies
    • Purmal A, Valeri CR, Dzik W, et al. Process for the preparation of pathogen-inactivated RBC concentrates by using PEN 110 chemistry: preclinical studies. Transfusion 2002; 42:139-145
    • (2002) Transfusion , vol.42 , pp. 139-145
    • Purmal, A.1    Valeri, C.R.2    Dzik, W.3
  • 39
    • 0142135467 scopus 로고    scopus 로고
    • Pathogen inactivation of RBCs: PEN110 reproductive toxicology studies
    • Chapman JR, Moore K, Butterworth BE: Pathogen inactivation of RBCs: PEN110 reproductive toxicology studies. Transfusion 2003; 43:1386-1393
    • (2003) Transfusion , vol.43 , pp. 1386-1393
    • Chapman, J.R.1    Moore, K.2    Butterworth, B.E.3
  • 40
    • 0036480515 scopus 로고    scopus 로고
    • Production of pathogen-inactivated RBC concentrates using PEN110 chemistry: a Phase 1 clinical study
    • AuBuchon JP, Pickard CA, Herschel LH, et al. Production of pathogen-inactivated RBC concentrates using PEN110 chemistry: a Phase 1 clinical study. Transfusion 2002; 42:146-152
    • (2002) Transfusion , vol.42 , pp. 146-152
    • AuBuchon, J.P.1    Pickard, C.A.2    Herschel, L.H.3
  • 41
    • 6444245559 scopus 로고    scopus 로고
    • Broad-spectrum virus reduction in RBC concentrates using INACTINE™ PEN110 chemistry
    • Lazo A, Tassello J, Jayarama V, et al. Broad-spectrum virus reduction in RBC concentrates using INACTINE™ PEN110 chemistry. Vox Sang 2002; 83:313-323
    • (2002) Vox Sang , vol.83 , pp. 313-323
    • Lazo, A.1    Tassello, J.2    Jayarama, V.3
  • 42
    • 0041428185 scopus 로고    scopus 로고
    • West Nile virus in blood: stability, distribution, and susceptibility to PEN110 inactivation
    • Mather T, Takeda T, Tassello J, et al. West Nile virus in blood: stability, distribution, and susceptibility to PEN110 inactivation. Transfusion 2003; 43:1029-1037
    • (2003) Transfusion , vol.43 , pp. 1029-1037
    • Mather, T.1    Takeda, T.2    Tassello, J.3
  • 43
    • 1842614993 scopus 로고    scopus 로고
    • Development of a sensitive PCR inhibition method to demonstrate HBV nucleic acid inactivation
    • Aytay S, Ohagen A, Busch MR, et al. Development of a sensitive PCR inhibition method to demonstrate HBV nucleic acid inactivation. Transfusion 2004; 44:476-484
    • (2004) Transfusion , vol.44 , pp. 476-484
    • Aytay, S.1    Ohagen, A.2    Busch, M.R.3
  • 44
    • 0036782763 scopus 로고    scopus 로고
    • Inactivation of HIV in blood
    • Ohagen A, Gibaja V, Aytay S, et al. Inactivation of HIV in blood. Transfusion 2002; 42:1308-1317
    • (2002) Transfusion , vol.42 , pp. 1308-1317
    • Ohagen, A.1    Gibaja, V.2    Aytay, S.3
  • 45
    • 0037321529 scopus 로고    scopus 로고
    • Prevention of Yersinia enterocolitica, Psudomonas fluorescens, and Pseudomonas putida outgrowth in deliberately inoculated blood by a novel pathogen-reduction process
    • Zavizion B, Serebryanik D, Serebryanik I, et al. Prevention of Yersinia enterocolitica, Psudomonas fluorescens, and Pseudomonas putida outgrowth in deliberately inoculated blood by a novel pathogen-reduction process. Transfusion 2003; 43:135-142
    • (2003) Transfusion , vol.43 , pp. 135-142
    • Zavizion, B.1    Serebryanik, D.2    Serebryanik, I.3
  • 46
    • 7944223376 scopus 로고    scopus 로고
    • Inactivation of gram-negative and gram-positive bacteria in RBC concentrates using INACTINE PEN110 chemistry
    • Zavizion B, Serebryanik D, Chapman J, et al. Inactivation of gram-negative and gram-positive bacteria in RBC concentrates using INACTINE PEN110 chemistry. Vox Sang 2004; 87:143-149
    • (2004) Vox Sang , vol.87 , pp. 143-149
    • Zavizion, B.1    Serebryanik, D.2    Chapman, J.3
  • 47
    • 2342496703 scopus 로고    scopus 로고
    • Inactivation of protozoan parasites in red blood cells using INACTINE PEN110 chemistry
    • Zavizion B, Pereira M, de MeloJorge M, et al. Inactivation of protozoan parasites in red blood cells using INACTINE PEN110 chemistry. Transfusion 2004; 44:731-738
    • (2004) Transfusion , vol.44 , pp. 731-738
    • Zavizion, B.1    Pereira, M.2    de MeloJorge, M.3
  • 48
    • 0024452434 scopus 로고
    • Induction of genetic duplications and frameshift mutations in Salmonella typhimurium by acridines and acridine mustards: dependence on covalent binding of the mutagen to DNA
    • Hoffmann GR, Freemer CS, Parente LA: Induction of genetic duplications and frameshift mutations in Salmonella typhimurium by acridines and acridine mustards: dependence on covalent binding of the mutagen to DNA. Mol Gen Genet 1989; 218:377-383
    • (1989) Mol Gen Genet , vol.218 , pp. 377-383
    • Hoffmann, G.R.1    Freemer, C.S.2    Parente, L.A.3
  • 49
    • 33748949444 scopus 로고    scopus 로고
    • Viability of RBCs prepared with S-303 pathogen inactivation treatment
    • Rios JA, Hambleton J, Viele M, et al. Viability of RBCs prepared with S-303 pathogen inactivation treatment. Transfusion 2005; 46:1778-1786
    • (2005) Transfusion , vol.46 , pp. 1778-1786
    • Rios, J.A.1    Hambleton, J.2    Viele, M.3
  • 50
    • 33745238335 scopus 로고    scopus 로고
    • INTERCEPT red blood cells are not genotoxic or carcinogenic in a series of in vitro and in vivo tests
    • (abstract 4055)
    • Ciaravino V, Stassinopoulos A, Singh Y, et al. INTERCEPT red blood cells are not genotoxic or carcinogenic in a series of in vitro and in vivo tests. Blood 2002; 100(Suppl 1):143b (abstract 4055)
    • (2002) Blood , vol.100 , Issue.SUPPL. 1
    • Ciaravino, V.1    Stassinopoulos, A.2    Singh, Y.3
  • 51
    • 78650315329 scopus 로고    scopus 로고
    • Helinx® technology inactivates pathogens of emerging importance in red blood cell concentrates
    • (abstract 3020)
    • Dupuis K, Bernard K, Jones S, et al. Helinx® technology inactivates pathogens of emerging importance in red blood cell concentrates. Blood 2003; 102(Suppl):816a (abstract 3020)
    • (2003) Blood , vol.102 , Issue.SUPPL.
    • Dupuis, K.1    Bernard, K.2    Jones, S.3
  • 52
    • 4243449823 scopus 로고    scopus 로고
    • Bacterial inactivation in leukoreduced PRBC treated with HELINX™
    • (abstract S139-0401)
    • Stassinopoulos A, Mababangloob RS, Dupuis KW, et al. Bacterial inactivation in leukoreduced PRBC treated with HELINX™. Transfusion 2000; 40(Suppl):38S (abstract S139-0401)
    • (2000) Transfusion , vol.40 , Issue.SUPPL.
    • Stassinopoulos, A.1    Mababangloob, R.S.2    Dupuis, K.W.3
  • 53
    • 0003302493 scopus 로고    scopus 로고
    • Inactivation of pathogens in packed red blood cell (PRBC) concentrates using S-303
    • (abstract 1820)
    • Cook D, Stassinopoulos A, Merrit J, et al. Inactivation of pathogens in packed red blood cell (PRBC) concentrates using S-303. Blood 1997; 90(Suppl):409a (abstract 1820)
    • (1997) Blood , vol.90 , Issue.SUPPL.
    • Cook, D.1    Stassinopoulos, A.2    Merrit, J.3
  • 54
    • 33644650468 scopus 로고    scopus 로고
    • Therapeutic efficacy and safety of red blood cells treated with a chemical process (S-303) for pathogen inactivation: a Phase III clinical trial in cardiac surgery patients
    • Benjamin RJ, McCullough J, Mintz PD, et al. Therapeutic efficacy and safety of red blood cells treated with a chemical process (S-303) for pathogen inactivation: a Phase III clinical trial in cardiac surgery patients. Transfusion 2005; 45:1739-1749
    • (2005) Transfusion , vol.45 , pp. 1739-1749
    • Benjamin, R.J.1    McCullough, J.2    Mintz, P.D.3
  • 55
    • 31044443784 scopus 로고    scopus 로고
    • Elimination of immunoreactivity of RBCs treated with a modified S-303 pathogen inactivation process
    • (abstract 2703)
    • Stassinopoulos A, Schott MA, Castro GM, et al. Elimination of immunoreactivity of RBCs treated with a modified S-303 pathogen inactivation process. Blood 2004; 105(Suppl):738a (abstract 2703)
    • (2004) Blood , vol.105 , Issue.SUPPL.
    • Stassinopoulos, A.1    Schott, M.A.2    Castro, G.M.3
  • 56
    • 77649191792 scopus 로고    scopus 로고
    • Treatment of whole blood (WB) and red blood cells (RBC) with S-303 inactivates pathogens and retains in vitro quality of stored RBC
    • Mufti NA, Erickson AC, North AK, et al. Treatment of whole blood (WB) and red blood cells (RBC) with S-303 inactivates pathogens and retains in vitro quality of stored RBC. Biologicals 2010; 38:14-19
    • (2010) Biologicals , vol.38 , pp. 14-19
    • Mufti, N.A.1    Erickson, A.C.2    North, A.K.3
  • 57
    • 77649336975 scopus 로고    scopus 로고
    • Design and development of a method for the reduction of infectious pathogen load and inactivation of white blood cells in whole blood products
    • Goodrich RP, Doane S, Reddy HL: Design and development of a method for the reduction of infectious pathogen load and inactivation of white blood cells in whole blood products. Biologicals 2010; 38:20-30
    • (2010) Biologicals , vol.38 , pp. 20-30
    • Goodrich, R.P.1    Doane, S.2    Reddy, H.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.