Thiazole orange, a DNA-binding photosensitizer with flexible structure, can inactivate pathogens in red blood cell suspensions while maintaining red cell storage properties

Transfusion

Volumn 46, Issue 2, 2006, Pages 213-219

  Skripchenko, Andrey ^a,b   Wagner, Stephen J ^a   Thompson Montgomery, Dedeene ^a   Awatefe, Helen ^a  

^a HOLLAND LABORATORY   (United States)

^b AMERICAN RED CROSS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYANINE DYE; ERYTHROSOL; INTERCALATING AGENT; MISCELLANEOUS DRUGS AND AGENTS; PHOTOSENSITIZING AGENT; POTASSIUM; REACTIVE OXYGEN METABOLITE; THIAZOLE ORANGE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL DNA; BENZOTHIAZOLE DERIVATIVE; FLUORESCENT DYE; QUINOLINE DERIVATIVE; THIAZOLE DERIVATIVE; VIRUS DNA;

ANTIVIRAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; CELL SUSPENSION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG DNA BINDING; ERYTHROCYTE MEMBRANE; ERYTHROCYTE PRESERVATION; HEMATOCRIT; HEMOLYSIS; HUMAN; HUMAN CELL; LEUKAPHERESIS; LIGHT; MEMBRANE BINDING; NONHUMAN; OXIDATIVE STRESS; OXYGENATION; PATHOGENESIS; POTASSIUM TRANSPORT; VIRUS INACTIVATION; BACTERIAL INFECTION; BINDING COMPETITION; BLOOD STORAGE; BLOODBORNE BACTERIUM; CHEMISTRY; CRYOPRESERVATION; CYTOLOGY; DRUG EFFECT; ERYTHROCYTE; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; VIRUS INFECTION;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BENZOTHIAZOLES; BINDING, COMPETITIVE; BLOOD PRESERVATION; BLOOD-BORNE PATHOGENS; CRYOPRESERVATION; DNA, BACTERIAL; DNA, VIRAL; ERYTHROCYTES; FLUORESCENT DYES; HUMANS; MICROBIAL VIABILITY; PHOTOSENSITIZING AGENTS; QUINOLINES; THIAZOLES; VIRUS DISEASES; VIRUS INACTIVATION;

EID: 33644848731     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2006.00703.x     Document Type: Article

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