Treatment of whole blood (WB) and red blood cells (RBC) with S-303 inactivates pathogens and retains in vitro quality of stored RBC

Biologicals

Volumn 38, Issue 1, 2010, Pages 14-19

  Mufti, N A ^a   Erickson, A C ^a   North, A K ^a   Hanson, D ^a   Sawyer, L ^a   Corash, L M ^a   Lin, L ^a  

^a CERUS CORPORATION   (United States)

Author keywords

Pathogen inactivation; Psoralen; Red blood cells; S 303; Whole blood

Indexed keywords

ALKYLATING AGENT; FRANGIBLE ANCHOR LINKER EFFECTOR COMPOUND; GLUTATHIONE; S 303; UNCLASSIFIED DRUG;

ADENOVIRUS 5; ARTICLE; BLOOD TRANSFUSION; BLUETONGUE ORBIVIRUS; BOVINE DIARRHEA VIRUS; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE PRESERVATION; ERYTHROCYTE TRANSFUSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; SERRATIA MARCESCENS; STAPHYLOCOCCUS EPIDERMIDIS; VIRUS INACTIVATION; YERSINIA ENTEROCOLITICA;

ACRIDINES; ALKYLATING AGENTS; ANIMALS; BLOOD; BLOOD PRESERVATION; BLOOD-BORNE PATHOGENS; CATTLE; CELLS, CULTURED; COLONY COUNT, MICROBIAL; DISINFECTANTS; DISINFECTION; ERYTHROCYTES; ESCHERICHIA COLI; FEASIBILITY STUDIES; HUMANS; MATCHED-PAIR ANALYSIS; NITROGEN MUSTARD COMPOUNDS; QUALITY CONTROL; STAPHYLOCOCCACEAE; YERSINIA ENTEROCOLITICA;

BACTERIA (MICROORGANISMS); BLUETONGUE VIRUS; BOVINAE; HUMAN ADENOVIRUS TYPE 5; SERRATIA MARCESCENS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; YERSINIA ENTEROCOLITICA;

EID: 77649191792     PISSN: 10451056     EISSN: 10958320     Source Type: Journal    
DOI: 10.1016/j.biologicals.2009.10.019     Document Type: Article

References (35)

1. Mohammed H., Linnen J.M., Muñoz-Jordán J.L., Tomashek K., Foster G., Broulik A.S., et al. Dengue virus in blood donations, Puerto Rico, 2005. Transfusion 48 (2008) 1348-1354
2. Tambyah P.A., Koay E.S., Poon M.L., Lin R.V., and Ong B.K. Transfusion-Transmitted Dengue Infection Study Group. Dengue hemorrhagic fever transmitted by blood transfusion. N Eng J Med 359 (2008) 1526-1527
3. Benjamin R.J., and Wagner S.J. The residual risk of sepsis: modeling the effect of concentration on bacterial detection in two-bottle culture systems and an estimation of false-negative culture rates. Transfusion 47 (2007) 1381-1389
4. Yomtovian R., Tomasulo P., and Jacobs M.R. Platelet bacterial contamination: assessing progress and identifying quandries in a rapidly evolving field. Transfusion 47 (2007) 1340-1346
5. Leiby D.A. Babesiosis and blood transfusion: flying under the radar. Vox Sang 90 (2006) 157-165
6. Triulzi D., Duquesnoy R., Nichols L., Clark K., Jukic D., Zeevi A., et al. Fatal transfusion-associated graft-versus-host disease in an immunocompetent recipient of a volunteer unit of red cells. Transfusion 6 (2006) 885-888
7. Nichols W.G., Price T.H., Gooley T., Corey L., and Boeckh M. Transfusion-transmitted cytomegalovirus infection after receipt of leukoreduced blood products. Blood 101 (2003) 4195-4200
8. Klein H.G., Anderson D., Bernardi M.J., Cable R., Carey W., Hoch J.S., et al. Pathogen inactivation: making decisions about new technologies: report of a consensus conference. Transfusion 47 (2007) 2338-2347
9. Bracey A.W. Advisory Committee on Blood Safety and Availability Recommendation, Department of Health and Human Services (2008). http://www.hhs.gov/ophs/bloodsafety/index.html
10. Webert KE, Cserti CM, Hannon J, Lin Y, Pavenski K, Pendergrast JM, et al. Proceedings of a consensus conference: pathogen inactivation - making decisions about new technologies. Transfusion Med Reviews 2008;22:1-34.
11. Charrel R.N., de Lamballerie X., and Raoult D. Chikungunya outbreaks - the globalization of vectorborne diseases. N Engl J Med 356 (2007) 769-771
12. Brouard C., Bernillon P., Quatresous I., Pillonel J., Assal A., De Valk H., et al. Estimated risk of Chikungunya viremic blood donation during an epidemic on Reunion Island in the Indian Ocean, 2005 to 2007. Transfusion 48 (2008) 1333-1341
13. Enserink M. A mosquito goes global. Science 320 (2008) 864-866
14. Osselaer J.C., Cazenave J.P., Lambermont M., Garraud O., Hidajat M., Barbolla L., et al. An active haemovigilance programme characterizing the safety profile of 7437 platelet transfusions prepared with amotosalen photochemical treatment. Vox Sang 94 (2008) 315-323
15. Osselaer J.C., Messe N., Hervig T., Bueno J., Castro E., Espinosa A., et al. A prospective observational cohort safety study of 5,106 platelet transfusions using components prepared with photochemcial pathogen inactivation treatment. Transfusion 48 (2008) 1061-1071
16. Osselaer J.C., Doyen C., Defoin L., Debry C., Goffaux M., Messe N., et al. Universal adoption of pathogen inactivation of platelet components: impact on platelet and red blood cell component use. Transfusion 49 (2009) 1412-1422
17. Rasonglès P., Angelini-Tibert M.F., Simon P., Currie C., Isola H., Kientz D., et al. Transfusion of platelet components prepared with photochemical pathogen inactivation treatment during a Chikungunya Virus epidemic in Ile de La Reunion. Transfusion 49 (2009) 1083-1091
18. Singh Y., Sawyer L.S., Pinkoski L.S., Dupuis K.W., Hsu J.C., Lin L., et al. Photochemical treatment of plasma with amotosalen and UVA light inactivates pathogens while retaining coagulation function. Transfusion 46 (2006) 1168-1177
19. Cazenave J.P., Osselaer J.C., Waller C., Jacquet M., Lin L., Corash L., et al. An active hemovigilance program utilizing and EDC system to assess safety of 2994 plasma transfusions prepared with the INTERCEPT Blood System. Transfusion 48 S2 (2008) 29A
20. Bryant B.J., and Klein H.G. Pathogen inactivation: the definitive safeguard for the blood supply. Arch Pathol Lab Med 131 (2007) 719-733
21. Rios J.A., Hambleton J., Viele M., Rugg N., Sindermann G., Greenwalt T., et al. Viability of red cells prepared with S-303 pathogen inactivation treatment. Transfusion 46 (2006) 1778-1786
22. Benjamin R.J., McCullough J., Mintz P.D., Snyder E., Spotnitz W.D., Rizzo R.J., et al. Therapeutic efficacy and safety of red blood cells treated with a chemical process (S-303) for pathogen inactivation: a Phase III clinical trial in cardiac surgery patients. Transfusion 45 11 (2005) 1739-1749
23. Cancelas J.A., Dumont L., Herschel L., Roger J., Rugg N., Garratty G., et al. A randomized, controlled, 2-period crossover study of recovery and lifespan of radiolabeled autologous 35-day-old red blood cells prepared with a modified S-303 treatment for pathogen inactivation. Vox Sang 95 S1 (2008) 2A
24. Beutler E. Back to the future in RBC preservation. Transfusion 40 8 (2000) 893-895
25. Lew V.L., Tiffert T., and Ginsburg H. Excess hemoglobin digestion and the osmotic stability of Plasmodium falciparum-infected red blood cells. Blood 101 10 (2003) 4189-4194
26. Lin L., Cook D.N., Wiesehahn G.P., Alfonso R., Behrman B., Cimino G.D., et al. Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light. Transfusion 37 (1997) 423-435
27. Högman C.F., de Verdier C.H., Ericson A., Hedlund K., and Sandhagen B. Studies on the mechanism of human red cell loss of viability during storage at +4 degrees C in vitro. I. Cell shape and total adenylate concentration as determinant factors for posttransfusion survival. Vox Sang 48 5 (1985) 257-268
28. American Association of Blood Banks. AABB technical manual. 15th ed. (2005), AABB Bethesda, Maryland
29. Council of Europe. Guide to the Preparation, Use, and Quality Assurance of Blood Components. 13th ed. (2007), Strabourg Cedex: Council of Europe Publishing
30. Clark M.R., Mohandas N., Feo C., Jacobs M.S., and Shohet S.B. Separate mechanisms of deformability loss in ATP-depleted and Ca-loaded erythrocytes. J Clin Invest 67 2 (1981) 531-539
31. Farges E., Grebe R., and Baumann M. Viscoelastic and biochemical properties of erythrocytes during storage with SAG-M at +4 degrees C. Clin Hemorheol Microcirc 27 1 (2002) 1-11
32. d'Onofrio G., Chirillo R., Zini G., Caenaro G., Tommasi M., and Micciulli G. Simultaneous measurement of reticulocyte and red blood cell indices in healthy subjects and patients with microcytic and nacrocytic anemia. Blood 85 3 (1995) 818-823
33. Gulati G.L., Hyland L.J., Kocher W., and Schwarting R. Changes in automated complete blood cell count and differential leukocyte count results induced by storage of blood at room temperature. Arch Pathol Lab Med 126 (2002) 336-342
34. Wagner S.J., Friedman L.I., and Dodd R.Y. Transfusion-associated bacterial sepsis. Clin Microbiol Rev 7 (1994) 290-302
35. Hillyer C.D., Josephson C.D., Blajchman M.A., Vostal J.G., Epstein J.S., and Goodman J.L. Bacterial contamination of blood components: risks, strategies, and regulation: joint ASH and AABB educational session in transfusion medicine. Hematology Am Soc Hematol Educ Program (2003) 575-589