Ordered subset analysis identifies loci influencing lung cancer risk on chromosomes 6q and 12q

Cancer Epidemiology Biomarkers and Prevention

Volumn 19, Issue 12, 2010, Pages 3157-3166

  Fang, Shenying ^a   Pinney, Susan M ^b   Bailey Wilson, Joan E ^c   De Andrade, Mariza A ^d   Li, Yafang ^a   Kupert, Elena ^b   You, Ming ^e   Schwartz, Ann G ^f   Yang, Ping ^d   Anderson, Marshall W ^b   Amos, Christopher I ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d Mayo Clinic College of Medicine   (United States)

^e WASHINGTON UNIVERSITY   (United States)

^f WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CHROMOSOME 12Q; CHROMOSOME 14Q; CHROMOSOME 16Q; CHROMOSOME 5Q; CHROMOSOME 6Q; FAMILIAL CANCER; GENE LOCUS; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC SCREENING; GENOME ANALYSIS; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MONTE CARLO METHOD; PRIORITY JOURNAL; VALIDATION PROCESS;

CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 6; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LOD SCORE; LUNG NEOPLASMS; MALE; MIDDLE AGED; RISK FACTORS;

EID: 78650380354     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-10-0792     Document Type: Article

References (40)

1. American Cancer Society. Cancer Statistics 2009 Presentation. Atlanta, GA: American Cancer Society. ; 2009.
2. International Agency for Research on Cancer (IARC). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans and their Supplements: A complete list. 83rd ed. World Health Organization. 12-19 February 2002. Available from: http://monographs.iarc.fr/ENG/Monographs/vol83/mono83-6B-4.pdf.
3. Samet JM. Epidemiology of Lung Cancer. New York: M. Dekker; 1994.
4. Mattson ME, Pollack ES, Cullen JW. What are the odds that smoking will kill you. Am J Public Health 1987;77(4):425-31.
5. Etzel CJ, Amos CI, Spitz MR. Risk for smoking-related cancer among relatives of lung cancer patients. Cancer Res 2003;63(23):8531-5.
6. Jonsson S. Familial risk of lung carcinoma in the Icelandic population. JAMA 2004;292(24):2977-83.
7. Ooi WL, Elston RC, Chen VW, Bailey-Wilson JE, Rothschild H. Increased Familial Risk for Lung-Cancer. J Natl Cancer Inst 1986;76(2):217-22.
8. Xu HY, Spitz MR, Amos CI, Shete S. Complex segregation analysis reveals a multigene model for lung cancer. Hum Genet 2005;116(1-2):121-7.
9. Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Wiest JS, et al. A major lung cancer susceptibility locus maps to chromosome 6q23-25. Am J Hum Gen 2004;75(3):460-74.
10. Ott J. Linkage analysis and family classification under heterogeneity. Ann Hum Genetics 1983;47 (Oct):311-20.
11. Morton N. The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type. Am J Hum Genetics 1956;8 (2):80-96.
12. Hall JM, Lee MK, Newman B, Morrow JE, Anderson LA, Huey B, et al. Linkage of early-onset familial breast-cancer to chromosome-17Q21. Science 1990;250(4988):1684-9.
13. Hauser ER, Watanabe RM, Duren WL, Bass MP, Langefeld CD, Boehnke M. Ordered subset analysis in genetic linkage mapping of complex traits. Genet Epidemiol 2004;27(1):53-63.
14. Scott WK, Hauser ER, Schmechel DE, Welsh-Bohmer KA, Small GW, Roses AD, et al. Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22. Am J of Hum Genetics 2003;73(5):1041-51.
15. Reck BH, Mukhopadhyay N, Tsai HJ, Weeks DE. Analysis of alcohol dependence phenotype in the COGA families using covariates to detect linkage. BMC Genetics 2005;6(Suppl 1):S143.
16. Sale MM, Lu LY, Spruill IJ, Fernandes JK, Lok KH, Divers J, et al. Genome-wide linkage scan in Gullah-speaking African American families with type 2 diabetes The Sea Islands Genetic African American Registry (Project SuGAR). Diabetes 2009;58(1):260-7.
17. Amos CI, Pinney SM, Li Y, Kupert E, Lee J, de Andrade MA, et al. A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers. Cancer Res 2010;70 (6):2359-67.
18. Speer MC. Use of LINKAGE Programs for linkage analysis. Curr Prot Hum Genet 2006. 1.7.1-1.7.50
19. Weeks DE, Sobel E, Oconnell JR, Lange K. Computer-programs for multilocus haplotyping of general pedigrees. Am J Hum Genet 1995; 56(6):1506-7.
20. McLaughlin L. CAGE Program. Fox Chase Cancer Center Philadelphia, PA: 1997.
21. Browning BL. FLOSS: Flexible ordered subset analysis for linkage mapping of complex traits. Bioinformatics 2006;22(4):512-3.
22. Jurg Ott. Analysis of Human Genetic Linkage. Revised ed. Baltimore, MD: The Johns Hopkins University Press; 1991. p. 74-6.
23. Lander E, Kruglyak L. Genetic dissection of complex traits - guidelines for interpreting and reporting linkage results. Nat Genetics 1995;11 (3):241-7.
24. You M, Wang DL, Liu PY, Vikis H, James M, Lu Y, et al. Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res 2009;15(8):2666-74.
25. Rajski M, Zanetti-Dallenbach R, Vogel B, Herrmann R, Rochlitz C, Buess M. IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients. BMC Med 2010;8:1.
26. Yu H, Spitz MR, Mistry J, Gu J, Hong WK, Wu X. Plasma levels of insulin-like growth factor-I and lung cancer risk: A Case-Control Analysis. J Natl Cancer Inst 1999;91(2):151-6.
27. Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: Biological actions. Endocr Rev 1995;16(1):3-34.
28. Chan JM, Stampfer MJ, Giovannucci E, Gann PH, Ma J, Wilkinson P, et al. Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study. Science 1998;279(5350):563-6.
29. Hakam A, Yeatman TJ, Lu L, Mora L, Marcet G, Nicosia SV, et al. Expression of insulin-like growth factor-1 receptor in human colorectal cancer. Hum Pathol 1999;30(10):1128-33.
30. Hankinson SE, Willett WC, Colditz GA, Hunter DJ, Michaud DS, Deroo B, et al. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 1998;351(9113):1393-6.
31. Sato M, Mori Y, Sakurada A, Fujimura S, Horii A. The H-cadherin (CDH13) gene is inactivated in human lung cancer. Hum Genetics 1998;103(1):96-101.
32. Lee SW. H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer. Nat Med 1996;2 (7):776-82.
33. Kawakami M, Staub J, Cliby W, Hartmann L, Smith DI, Shridhar V. Involvement of H-cadherin (CDH13) on 16q in the region of frequent deletion in ovarian cancer. Int J Oncol 1999;15(4):715-20.
34. Takeuchi T, Misaki A, Liang SB, Tachibana A, Hayashi N, Sonobe H, et al. Expression of T-cadherin (CDH13, H-cadherin) in human brain and its characteristics as a negative growth regulator of epidermal growth factor in neuroblastoma cells. J Neurochem 2000;74(4):1489-97.
35. Sato M, Mori Y, Sakurada A, Fukushige S, Ishikawa Y, Tsuchiya E, et al. Identification of a 910-Kb region of common allelic loss in chromosome bands 16q24.1-q24.2 in human lung cancer. Genes Chromo & Cancer 1998;22(1):1-8.
36. Li BCY, Chan WY, Li CYS, Chow C, Ng EKW, Chung SCS. Allelic loss of chromosome 6q in gastric carcinoma. Diagn Mol Pathol 2003;12 (4):193-200.
37. Virmani AK, Fong KM, Kodagoda D, McIntire D, Hung J, Tonk V, et al. Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types. Genes Chromo & Cancer 1998;21(4):308-19.
38. Seregni E, Botti C, Lombardo C Cantoni A, Bogni A, Cataldo I, et al. Pattern of mucin gene expression in normal and neoplastic lung tissues. Anticancer Res 1996;16(4B):2209-13.
39. Boyce B, Rakha E, Abd El-Rehim D, Green A, Paish C, Ellis I. The expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer. J Pathol 2005; 205:5.
40. Rakha EA, Boyce RWG, Abd El-Rehim D, Kurien T, Green AR, Paish EC, et al. Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer. Modern Pathol 2005;18(10):1295-304.