Protective efficacy of recombinant urease B and aluminum hydroxide against Helicobacter pylori infection in a mouse model

FEMS Immunology and Medical Microbiology

Volumn 60, Issue 2, 2010, Pages 142-146

  Bégué, Rodolfo E ^a   Sadowska Krowicka, Halina ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adjuvant; Bacterial vaccine; Helicobacter pylori; Mouse model; Urease B

Indexed keywords

ALUMINUM HYDROXIDE; RECOMBINANT PROTEIN; RECOMBINANT UREASE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; IMMUNOGENICITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ALUMINUM HYDROXIDE; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL VACCINES; DISEASE MODELS, ANIMAL; DNA; FREUND'S ADJUVANT; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INJECTIONS, INTRAMUSCULAR; INJECTIONS, SUBCUTANEOUS; MICE; MICE, INBRED BALB C; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; UREASE; VACCINES, SYNTHETIC;

EID: 78650362271     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2010.00726.x     Document Type: Article

References (27)

1. Bégué RE & Moll A (2009) Immunogenicity of recombinant Helicobacter pylori urease B administered by various routes and with different adjuvants. Open Vaccine J 2: 28-32.
2. Bégué RE, Manning J & Correa H (2006) Real-time PCR for quantification of Helicobacter felis in mouse stomach. Southern Med J 99: 1306-1307.
3. Bégué RE, Cruz AR, Ramgoolam A & Breslin MB (2007) Immunogenicity of Helicobacter pylori urease B protein and DNA vaccines in a mouse model. J Pediatr Gastr Nutr 45: 493-496.
4. Blanchard TG & Czinn SJ (2000) Immunology of Helicobacter pylori and prospects for a vaccine. Gastroenterol Clin N 29: 671-685.
5. Casswall TH, Nillson HO, Björck L, Sjostedt S, Xu L, Nord CK, Boren T, Wadstrom T & Hammarstrom L (2002) Bovine anti-Helicobacter pylori antibodies for oral immunotherapy. Scand J Gastroentero 37: 1380-1385.
6. Chen M, Lee A & Hazell S (1992) Immunization against Helicobacter infection in a mouse/Helicobacter felis model. Lancet 339: 1120-1121.
7. Czinn SJ & Nedrud JG (1991) Oral immunization against Helicobacter pylori. Infect Immun 59: 2359-2363.
8. Czinn SJ, Cai A & Nedrud JG (1993) Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization. Vaccine 11: 637-642.
9. Eaton KA, Brooks CL, Morgan DR & Krakowka S (1991) Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets. Infect Immun 59: 2470-2475.
10. Ferrero RL, Thiberge JM, Huerre M & Labigne A (1994) Recombinant antigens prepared from urease subunits of Helicobacter spp.: evidence of protection in a mouse model of gastric infection. Infect Immun 62: 4981-4989.
11. Futagami S, Takahashi H, Norose Y & Kobayashi M (1998) Systemic and local immune responses against Helicobacter pylori urease in patients with chronic gastritis: distinct IgA and IgG productive sites. Gut 43: 168-175.
12. Gorell RJ & Robins-Browne RM (2009) Antibody-mediated protection against infection with Helicobacter pylori in a suckling mouse model of passive immunity. Infect Immun 77: 5116-5129.
13. Kleanthous H, Myers GA, Georgakopoulos KM et al. (1998) Rectal and intranasal immunizations with recombinant urease induce distinct local and serum immune responses in mice and protect against Helicobacter pylori infection. Infect Immun 66: 2879-2886.
14. Kotloff KL, Szeiten MB, Wasserman SS, Losonsky GA, DiLorenzo SC & Walker RI (2001) Safety and immunogenicity of oral inactivated whole-cell Helicobacter pylori vaccine with adjuvant among volunteers with or without subclinical infection. Infect Immun 69: 3581-3590.
15. Kreiss C, Buclin T, Cosma M, Corthesy-Theulauz I & Michetti P (1996) Safety of oral immunization with recombinant urease in patients with Helicobacter pylori infection. Lancet 347: 1630-1631.
16. Lee CK, Soike K, Giannasca P, Hill J, Weltzin R, Kleanthous H, Blanchard J & Monath TP (1999) Immunization of rhesus monkeys with a mucosal prime, parenteral boost strategy protects against infection with Helicobacter pylori. Vaccine 17: 3072-3082.
17. Londoño-Arcila P, Freeman D, Kleanthous H et al. (2002) Attenuated Salmonella enteric serovar Typhi expressing urease effectively immunizes mice against Helicobacter pylori challenge as part of a heterologous mucosal priming-parenteral boosting vaccination regimen. Infect Immun 70: 5096-5106.
18. Michetti P, Corthesy-Theulaz I, Davin C, Haas R, Vaney AC, Heitz M, Bille J, Kraehenbuhl JP, Saraga E & Blum AL (1994) Immunization of BALB/c mice against Helicobacter felis infection with Helicobacter pylori urease. Gastroenterology 107: 1002-1011.
19. Michetti P, Kreiss C, Kotloff KL et al. (1999) Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori-infected adults. Gastroenterology 116: 804-812.
20. Moschos SA, Bramwell VW, Somavarapu S & Alpar HO (2006) Modulating the adjuvanticity by co-administration of muramyl di-peptide (MDP) or Quil-A. Vaccine 24: 1081-1086.
21. Roussel Y, Harris A, Lee MH & Wilks M (2007) Novel methods of quantitative real-time PCR data analysis in a murine Helicobacter pylori vaccine model. Vaccine 25: 2919-2929.
22. Suerbaum S & Michetti P (2002) Helicobacter pylori infection. New Engl J Med 347: 1175-1186.
23. Sutton P, Wilson J & Lee A (2000) Further development of a Helicobacter pylori mouse vaccination model. Vaccine 18: 2677-2685.
24. Thoreson ACE, Borre MB, Andersen LP, Elsborg L, Holck S, Conway P, Henrichsen J, Vuust J & Krogfelt KA (1995) Development of a PCR-based technique for detection of Helicobacter pylori. FEMS Immunol Med Mic 10: 325-334.
25. Weltzin R, Guy B, Thomas WD Jr & Giannasca PJ (2000) Parenteral adjuvant activities of Escherichia coli heat-labile toxin and its B subunit for immunization of mice against gastric Helicobacter pylori infection. Infect Immun 68: 2775-2782.
26. Wu C, Shi Y, Guo H, Zhou WY, Guo G, Xie QH, Mao XH, Tong WD & Zou QM (2008) Protection against Helicobacter pylori infection in Mongolian gerbil by intragastric or intramuscular administration of H. pylori multicomponent vaccine. Helicobacter 13: 191-199.
27. Zavala-Spinetti L, Breslin MB, Correa H & Bégué RE (2006) Construction and evaluation of a Helicobacter pylori urease B DNA vaccine. Helicobacter 11: 517-522.