Systemic and local immune responses against Helicobacter pylori urease in patients with chronic gastritis: Distinct IgA and IgG productive sites

Gut

Volumn 43, Issue 2, 1998, Pages 168-175

  Futagami, S ^a   Takahashi, H ^a   Norose, Y ^a   Kobayashi, M ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Antibody production; B lymphocytes; Chronic gastritis; Helicobacter pylori; Local immunity; Urease

Indexed keywords

ENZYME ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; UREASE;

ANTIBODY PRODUCTION; ANTIGEN DETECTION; ANTIGEN RECOGNITION; ARTICLE; CHRONIC GASTRITIS; CONTROLLED STUDY; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; STOMACH JUICE; STOMACH MUCOSA;

EID: 0031873541     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.43.2.168     Document Type: Article

References (43)

1. Blaser MJ. Gastric Campylobacter-like organisms, gastritis and peptic ulcer diseases. Gastroenterology 1987;93:371-83.
2. Dixon MF. Helicobacter pylori and peptic ulceration: histopathological aspects. J Gastroenterol Hepatol 1991;6:125-30.
3. Berstad AE, Brandtzaeg P, Stave R, et al. Epithelium related deposition of activated complement in Helicobacter pylori associated gastritis. Gut 1997;40:196-203.
4. Karttunen R, Karttunen T, Ekre H-P T, et al. Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis. Gut 1995;36:341-5.
5. Mai UEH, Perez-Perez GI, Wahl LM, et al. Soluble surface proteins from Helicobacter pylori activate monocytes/macrophages by lipopolysaccharide-independent mechanism. J Clin Invest 1991;87:894-900.
6. Futagami S, Takahashi H, Norose Y, et al. Analysis of immune response to Helicobacter pylori: identification of the protein recognized by anti-Helicobacter pylori antibodies from sera of patients with gastroduodenal diseases. Jpn J Gastroenterol 1994;91:2202-13.
7. Newell DG. Identification of the outer membrane proteins of Campylobacter pyloridis and antigenic cross-reactivity between C. pyloridis and C. jejuni. J Gen Microbiol 1987;133:163-70.
8. Dent JC, McNulty CAM, Uff JS, et al. Campylobacter pylori urease: a new serological test. Lancet 1988;i:1002.
9. Czinn S, Carr H, Sheffler L, et al. Serum IgG antibody to the outer membrane proteins of Campylobacter pylori in children with gastroduodenal disease. J Infect Dis 1989;159:586-9.
10. Eaton KA, Brooks CL, Morgan DR, et al. Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets. Infect Immun 1991;59:2470-5.
11. Eaton KA, Krakowka S. Effect of gastric pH on urease-dependent colonization of gnotobiotic piglets by Helicobacter pylori. Infect Immun 1994;62:3604-7.
12. Misiewicz JJ, Tytgat G, Goodwin CS, et al. The Sydney system: a new classification of gastritis. In: Working party reports of the 9th World Congress of Gastroenterology. Melbourne: Blackwell Scientific, 1989:1-10.
13. Price AB. The Sydney system: histological division. J Gastroenterol Hepatol 1991;6:209-22.
14. Marshall BJ, Warren JR, Francis GJ, et al. Rapid urease test in the management of Campylobacter pyloridis-associated gastritis. Am J Gastroenterol 1987;82:200-10.
15. Atherton JC, Spiller RC. The urea breath test for Helicobacter pylori. Gut 1994;35:723-5.
16. Gray SF, Wyatt JI, Rathbone BJ. Simplified techniques for identifying Campylobacter pyloridis. J Clin Pathol 1986;39:1279-80.
17. Whitehead R, Truelove SC, Gear MWL. The histological diagnosis of chronic gastritis in fibreoptic gastroscope biopsy specimens. J Clin Pathol 1972;25:1-11.
18. Clayton CL, Pallen MJ, Kleanthous H, et al. Nucleotide sequence of two genes from Helicobacter pylon encoding for urease subunits. Nucleic Acids Res 1989;18:362.
19. Nagata K, Mizuta T, Tonokatu Y, et al. Monoclonal antibodies against the native urease of Helicobacter pylori: synergistic inhibition of urease activity by monoclonal antibody combinations. Infect Immun 1992;60:4826-31.
20. Parsonnet J, Friedman GD, Orentreich N, et al. Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection. Gut 1997;40:297-301.
21. Kreuning J, Lindeman J, Biemond I, et al. Relation between IgG and IgA antibody titers against Helicobacter pylori in serum and severity of gastritis in asymptomatic subjects. J Clin Pathol 1994;47:227-31.
22. Pena AS, Endtz HPh, Offerhaus GJA, et al. Value of serology (ELISA and immunoblotting) for the diagnosis of Campylobacter pylori infection. Digestion 1989;44:131-41.
23. Kuipers FJ, Pena AS, van Kamp G, et al. Seroconversion for Helicobacter pylori. Lancet 1993;342:328-31.
24. Veenendaal RA, Götz JM, Schroijen V, et al. Diagnosis of Helicobacter pylori infection by specific gastric mucosal IgA and IgG pylori antibodies. J Clin Pathol 1995;48:990-3.
25. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
26. Peterson GL. A simplification of the protein assay method of Lowry et al which is more generally applicable. Anal Biochem 1977;83:346-56.
27. Matsukura N, Onda M, Tokunaga A, et al. Mucosal IgA antibody against Helicobacter pylori in chronic gastritis and intestinal metaplasia detected by the tes-tape method in resection specimens after gastrectomy for gastric cancer. Cancer 1995;75:1472-7.
28. Chen XG, Correa P, Offerhaus J, et al. Ultrastructure of the gastric mucosa harboring Campylobacter-like organisms. Am J Clin Pathol 1986;86:575-82.
29. Perez-Perez GI, Brown WR, Cover TL, et al. Correlation between serological and mucosal inflammatory responses to Helicobacter pylori. Clin Diagn Lab Immunol 1994;1:325-9.
30. Dunn BE, Roop II RM, Sung C-C, et al. Identification and purification of a cpn60 heat shock protein homolog from Helicobacter pylori. Infect Immun 1992;60:1946-51.
31. Evans DJ Jr, Evans DG, Engstrand L, et al. Urease-associated heat shock protein of Helicobacter pylori. Infect Immun 1992;60:2125-7.
32. Leunk RD, Ferguson MA, Morgan DR, et al. Antibody to cytotoxin in infection by Helicobacter pylori. J Clin Microbiol 1990;28:1181-4.
33. Covacci A, Censini S, Bugnoli M, et al. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci USA 1993;90:5791-5.
34. Crabtree JE, Shallcross TM, Wyatt JI, et al. Mucosal humoral immune response to Helicobacter pylori in patients with duodenitis. Dig Dis Sci 1991;36:1266-73.
35. Patel P, Mendall MA, Khulusi S, et al. Salivary antibodies to Helicobacter pylori: screening dyspeptic patients before endoscopy. Lancet 1994;344:511-12.
36. Crabtree JE, Figura N, Taylor JD, et al. Expression of 120 kilodalton protein and cytotoxicity in Helicobacter pylori. J Clin Pathol 1992;45:733-4.
37. Crabtree JE, Shallcross TM, Heatley RV, et al. Mucosal tumour necrosis factor α and interleukin-6 in patients with Helicobacter pylori-associated gastritis. Gut 1991;32:1473-7.
38. Kaetzel CS, Robinson JK, Chintalacharuvu KR, et al. The polymeric immunoglobulin receptor (secretory component) mediates transport of immune complexes across epithelial cells: a local defense function for IgA. Proc Natl Acad Sci USA 1991;88:8796-800.
39. Mazanec MB, Nedrud JG, Kaetzel CS, et al. A three-tiered view of the role of IgA in mucosal defense. Immunol Today 1993;14:430-5.
40. Wyatt JI, Rathbone BJ, Heatley RV. Local immune response to gastric Campylobacter in non-ulcer dyspepsia. J Clin Pathol 1986;39:863-70.
41. Negrini R, Lisato L, Cavazzini L, et al. Monoclonal antibodies for specific immunoperoxidase detection of Campylobacter pylori. Gastroenterology 1989;96:414-20.
42. Baum H, Davies H, Peakman M. Molecular mimicry in the MHC: hidden clues to autoimmunity? Immunol Today 1996;64:64-70.
43. Bienenstock J, Befus AD. Some thoughts on the biologic role of immunoglobulin A. Gastroenterology 1983;84:178-85.