Phenotypic enhancement of thymidylate synthetase pathway inhibitors following ablation of Neil1 DNA glycosylase/lyase

Cell Cycle

Volumn 9, Issue 24, 2010, Pages 4876-4883

  Taricani, Lorena ^a,b   Shanahan, Frances ^a   Pierce, Rob H ^a   Guzi, Timothy J ^a   Parry, David ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Antimetabolites; Base excision repair (BER); Cell cycle; Checkpoints; DNA repair; Neil1; Thymidylate synthetase

Indexed keywords

AMINOPTERIN; ATM PROTEIN; ATR PROTEIN; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 45; CELL CYCLE PROTEIN 6; CELL CYCLE PROTEIN 7; CLOFARABINE; CYTARABINE; DNA DIRECTED DNA POLYMERASE BETA; DNA GLYCOSYLTRANSFERASE; DOXORUBICIN; FLOXURIDINE; FLUOROURACIL; GEMCITABINE; HISTONE H2AX; MELPHALAN; METHOTREXATE; NEIL1 ENZYME; NOLATREXED; NUCLEIC ACID BINDING PROTEIN; PEMETREXED; PROTEIN RAD9; RAD17 PROTEIN; RALTITREXED; SMALL INTERFERING RNA; TEMOZOLOMIDE; THYMIDYLATE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; EXCISION REPAIR; GENETIC EPISTASIS; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PHENOTYPE;

EID: 78650334762     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.24.14155     Document Type: Article

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