The effect of fluoride treatment on bone mineral in rabbits

Calcified Tissue International

Volumn 64, Issue 4, 1999, Pages 345-351

  Chachra, D ^a,b   Turner, C H ^c   Dunipace, A J ^c   Grynpas, M D ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bone; Fluoride; Microhardness; Mineralization; Rabbit model

Indexed keywords

CALCIUM; CARBONIC ACID; FLUORIDE; PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE LEVEL; BONE MINERAL; BONE MINERALIZATION; BONE STRENGTH; BONE STRUCTURE; CALCIUM BONE LEVEL; CANCELLOUS BONE; CHEMICAL COMPOSITION; CONTROLLED STUDY; CORTICAL BONE; CRYSTAL STRUCTURE; DIET SUPPLEMENTATION; DOSE RESPONSE; FEMALE; FEMUR HEAD; NONHUMAN; PRIORITY JOURNAL; RABBIT; TREATMENT OUTCOME;

AGE FACTORS; ANIMALS; BONE AND BONES; BONE DENSITY; CALCIFICATION, PHYSIOLOGIC; CALCIUM; CARBONATES; FEMALE; FLUORIDES; PHOSPHATES; RABBITS;

EID: 0032947939     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900630     Document Type: Article

References (53)

1. Turner CH, Garetto LP, Dunipace AJ, Zhang W, Wilson ME, Grynpas MD, Chachra D, McClintock R, Peacock M, Stookey GK (1997) Fluoride treatment increased serum IGF-I, bone turnover, and bone mass, but not bone strength, in rabbits. Calcif Tissue Int 61:77-83
2. Rich C, Ensinck J (1961) Effect of sodium fluoride on calcium metabolism of human beings. Nature 191:184-185
3. Cheng P-T, Bader SM, Grynpas MD (1995) Biphasic sodium fluoride effects on bone and bone mineral: a review. Cells Mater 5:271-282
4. Mamelle N, Meunier PJ, Dusan R, Guillaume M, Martin JL, Gaucher A (1988) Risk-benefit ration of sodium fluoride treatment in primary vertebral osteoporosis. Lancet 2:361-365
5. Mamelle N, Meunier PJ, Netter P (1990) Fluoride and vertebral fractures. Lancet 336:243
6. Pak CYC, Sakhaee K, Piziak V, Peterson RD, Breslau NA, Boyd P (1994) Slow-release sodium fluoride in the management of post-menopausal osteoporosis: a randomized controlled trial. Ann Intern Med 120:625-632
7. Riggs BL, Hodgson SF, O'Fallon M, Chao EYS, Wahner HW, Muhs JM, Cedel SL, Melton LJ III (1990) Effect of fluoride treatment of the fracture rate in postmenopausal women with osteoporosis. N Engl J Med 322:802-809
8. Kleerekoper M, Peterson EL, Nelson DA, Phillips E, Schork MA, Tilley BC, Parfitt AM (1991) A randomized trial of sodium fluoride as a treatment for postmenopausal osteoporosis. Osteoporosis Int 1:155-161
9. Riggs BL (1993) Fluoride revisited. Res Clin Forums 15:35-39
10. Riggs BL, O'Fallon WM, Lane A, Hodgson SF, Wahner HW, Muhs J, Chao E, Melton LJ III (1994) Clinical trial of fluoride therapy in postmenopausal osteoporotic women: extended observations and additional analysis. J Bone Miner Res 9:265-275
11. Pak CYC, Zerwekh JE, Antich PP, Bell NH, Singer FR (1996) Slow-release sodium fluoride in osteoporosis. J Bone Miner Res 3:497-502
12. Riggs BL, Baylink DJ, Kleerekoper M, Lane JM, Melton LJ, Meunier PJ (1987) Incidence of hip fractures in osteoporotic women treated with sodium fluoride. J Bone Miner Res 2: 123-126
13. Riggs BL (1990) Theoretical considerations in the treatment of osteoporosis. In: Christiansen C, Overgaard K (eds) Osteoporosis 1990. Osteopress, Denmark, pp 1289-1293
14. Melton LJ III (1990) Fluoride in the prevention of osteoporosis and fractures. J Bone Miner Res 5(suppl 1):S163-S167
15. Deal CL (1997) Osteoporosis: prevention, diagnosis, and management. Am J Med 102:35S-39S
16. Grynpas MD (1990) Fluoride effects on bone crystals. J Bone Miner Res 5:S169-S175
17. Moreno EC, Kresak M, Zahradnik RT (1976) Physicochemical aspects of fluoride-apatite systems relevant to the study of caries. Caries Res 11(suppl 1):142-171
18. Grynpas MD, Cheng P-T (1988) Fluoride reduced the rate of dissolution of bone. Bone Miner 5:1-9
19. Farley JR, Tarbaux N, Hall S, Baylink DJ (1990) Mitogenic action(s) of fluoride on osteoblast line cells: determinants of the response in vitro. J Bone Miner Res 5(suppl 1):S107-S113
20. Gruber HE, Baylink DJ (1991) The effects of fluoride on bone. Clin Orthop Rel Res 267:264-277
21. Boivin G, Chavassieux P, Chapuy M-C, Baud CA, Meunier PJ (1989) Skeletal fluorosis: histomorphometric analysis of bone changes and bone fluoride content in 29 patients. Bone 10: 89-99
22. Bonjour JP, Caverzasio J, Rizzoli R (1993) Effect of fluoride on bone cells. Res Clin Forums 15:9-12
23. Boivin G, Meunier PJ (1990) Fluoride and bone: toxicological and therapeutic aspects. In: Cohen RD, Lewis B, Alberti KGMM, Denman AM (eds) The metabolic and molecular basis of acquired disease. Baillière Tindall, London, pp 1803-1823
24. Okuda A, Kanehisa J, Heersche JNM (1990) The effects of sodium fluoride on the resorptive activity of isolated osteoclasts. J Bone Miner Res 5 (suppl 1):S115-S120
25. Catanese J, Keaveny TM (1996) Role of collagen and hydroxyapatite in the mechanical behavior of bone tissue. J Bone Miner Res 11:S295
26. Grynpas MD, Hunter G (1988) Bone mineral and glycosaminoglycans in newborn and mature rabbits. J Bone Miner Res 3:159-164
27. Mernagh JR, Harrison JE, Hancock R, McNeill KG (1977) Measurement of fluoride in bone. Int J Appl Rad Isotopes 28:581-583
28. Chen PS, Toribora TY, Warner H (1956) Microdetermination of phosphorus. Anal Chem 28:1756-1758
29. Schwarzenbach G (1955) The complexones and their analytical application. Analyst 80:713-729
30. Engleman EE, Jackson LL, Norton DR (1985) Determination of carbonate carbon in geological materials by coulometric titration. Chem Geol 53:125-128
31. Klug H, Alexander L (1974) X-ray diffraction procedures for polycrystalline and amorphous materials. John Wiley and Sons, New York, pp 687-692
32. Serra J (1988) Image analysis and mathematical morphology, vol. 1. Academic Press, London
33. Compston JE, Mellish RWE, Garrahan NJ (1987) Age-related changes in iliac crest trabecular microanatomic bone structure in man. Bone 8:289-292
34. Lau K-HW, Akesson K, Libanati CR, Baylink DJ (1998) Osteogenic actions of fluoride: its therapeutic use for established osteoporosis. In: Whitfield JF, Morley P (eds) Anabolic treatments for osteoporosis. CRC Press, Boca Raton, pp 207-254
35. Lundy MW, Russell JE, Avery J, Wergedal JE, Baylink DJ (1992) Effect of sodium fluoride on bone density in chickens. Calcif Tissue Int 50:420-426
36. Grynpas MD, Holmyard DP, Pritzker KPH (1994) Bone mineralization and histomorphometry in biopsies of osteoporotic patients treated with fluoride. Cells Mater 4:287-297
37. Fratzl P, Schreiber S, Roschger P, Lafage M-H, Rodan G, Klaushofer K (1996) Effects of sodium fluoride and alendronate on the bone mineral in minipigs: a small-angle x-ray scattering and backscattered electron imaging study. J Bone Miner Res 11:248-253
38. Posner AS, Eanes ED, Harper RA, Zipkin I (1963) X-ray diffraction analysis of the effect of fluoride on human bone apatite. Arch Oral Biol 8:549-570
39. Eanes ED, Meyer JL (1978) The influence of fluoride on apatite formation from unstable supersaturated solutions at pH 7.4. J Dent Res 617-624
40. Stea S, Visentin M, Savarino L, Ciapetti G, Donati ME, Moroni A, Caja V, Pizzoferrato A (1995) Microhardness of bone at the interface with ceramic-coated metal implants. J Biomed Mater Res 29:695-699
41. Hodgskinson R, Currey JD, Evans GP (1989) Hardness, an indicator of the mechanical competence of cancellous bone. J Orthop Res 7:754-758
42. Weaver JK (1966) The microscopic hardness of bone. J Bone Jt Surg 48A:273-288
43. Grynpas MD, Simmons ED, Pritzker KPH, Hancock RV, Harrison JE (1986) Is fluoridated bone different from non-fluoridated bone? In: Yousuf Ali S (ed) Cell-mediated calcification and matrix vesicles. Elsevier Science Publishers, New York, pp 409-414
44. Yeni YN, Brown CU, Norman TL (1998) Influence of bone composition and apparent density on fracture toughness of the human femur and tibia. Bone 22:79-84
45. Currey JD, Brear K, Zioupos P (1996) The effect of ageing and changes in mineral content in degrading the toughness of human femora. J Biomech 29:257-260
46. Fratzl P, Roschger P, Eschberger J, Abendroth B, Klaushofer K (1994) Abnormal bone mineralization after fluoride treatment in osteoporosis: a small-angle x-ray scattering study. J Bone Miner Res 9:1541-1549
47. Walsh WR, Guzelsu N (1993) The role of ions and mineral-organic interfacial bonding on the compressive properties of cortical bone. Biomed Mater Eng 3:75-84
48. Walsh WR, Labrador DP, Kim HD, Guzelsu N (1994) The effect of in vitro fluoride ion treatment on the ultrasonic properties of cortical bone. Ann Biomed Eng 22:404-415
49. Ekstrand J, Spak C-J (1990) Fluoride pharmacokinetics: its implications in the fluoride treatment of osteoporosis. J Bone Miner Res 5 (suppl 1):S53-S61
50. Søgaard CH, Mosekilde Li, Richards A, Mosekilde Le (1994) Marked decrease in trabecular bone quality after five years of sodium fluoride therapy - assessed by biomechanical testing of iliac crest bone biopsies in osteoporotic patients. Bone 15: 393-399
51. Boivin G, Chapuy M-C, Baud CA, Meunier PJ (1988) Fluoride content in human iliac bone: results in controls, patients with fluorosis, and osteoporotic patients treated with fluoride. J Bone Miner Res 3:497-502
52. Zerwekh JE, Antich PP, Sakhaee K, Prior J, Gonzales J, Gottschalk F, Pak CYC (1992) Lack of deleterious effect of slow-release sodium fluoride treatment on cortical bone histology and quality in osteoporotic patients. Bone Miner 18: 65-76
53. Lundy MW, Stauffer M, Wergedal JE, Baylink DJ, Featherstone JDB, Hodgson SF, Riggs BL (1995) Histomorphometric analysis of iliac crest bone biopsies in placebo-treated versus fluoride-treated subjects. Osteoporosis Int 5:115-129