-
1
-
-
59949091205
-
Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application
-
Agnihotri SM, Vavia PR (2009) Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application. Nanomed-Nanotechnol Biol Med 5: 90-95.
-
(2009)
Nanomed-Nanotechnol Biol Med
, vol.5
, pp. 90-95
-
-
Agnihotri, S.M.1
Vavia, P.R.2
-
2
-
-
0026735598
-
The Relationship between Particle-Size and Solubility
-
Buckton G, Beezer AE (1992) The Relationship between Particle-Size and Solubility. Int J Pharm 82: R7-R10.
-
(1992)
Int J Pharm
, vol.82
-
-
Buckton, G.1
Beezer, A.E.2
-
3
-
-
0035263508
-
Complexes of Al(III) with 3′4′-dihydroxy-flavone: Characterization, theoretical and spectroscopic study
-
Cornard JP, Boudet AC, Merlin JC (2001) Complexes of Al(III) with 3′4′-dihydroxy-flavone: characterization, theoretical and spectroscopic study. Spectrochim Acta A Mol Biomol Spectrosc 57: 591-602.
-
(2001)
Spectrochim Acta a Mol Biomol Spectrosc
, vol.57
, pp. 591-602
-
-
Cornard, J.P.1
Boudet, A.C.2
Merlin, J.C.3
-
4
-
-
1642369552
-
Analgesic, antiinflammatory and CNS depressant activities of sesquiterpenes and a flavonoid glycoside from Polygonum viscosum
-
Datta BK, Datta SK, Chowdhury MM, Khan TH, Kundu JK, Rashid MA, Nahar L, Sarker SD (2004) Analgesic, antiinflammatory and CNS depressant activities of sesquiterpenes and a flavonoid glycoside from Polygonum viscosum. Pharmazie 59: 222-225. (Pubitemid 38391429)
-
(2004)
Pharmazie
, vol.59
, Issue.3
, pp. 222-225
-
-
Datta, B.K.1
Datta, S.K.2
Chowdhury, M.M.3
Khan, T.H.4
Kundu, J.K.5
Rashid, M.A.6
Nahar, L.7
Sarker, S.D.8
-
5
-
-
34547854225
-
Towards a photophysical model for 5-hydroxyflavone
-
del Valle JC (2006) Towards a photophysical model for 5-hydroxyflavone. J Chem Phys 124: 104506.
-
(2006)
J Chem Phys
, vol.124
, pp. 104506
-
-
Del Valle, J.C.1
-
6
-
-
35949004332
-
Acidichromism and ionochromism of luteolin and apigenin, the main components of the naturally occurring yellow weld: A spectrophotometric and fluorimetric study
-
Favaro G, Clementi C, Romani A, Vickackaite V (2007) Acidichromism and ionochromism of luteolin and apigenin, the main components of the naturally occurring yellow weld: a spectrophotometric and fluorimetric study. Fluoresc 17: 707-714.
-
(2007)
Fluoresc
, vol.17
, pp. 707-714
-
-
Favaro, G.1
Clementi, C.2
Romani, A.3
Vickackaite, V.4
-
8
-
-
58249109448
-
Formulation and pharmacokinetic evaluation of an asulacrine nanocrystalline suspension for intravenous delivery
-
Ganta S, Paxton JW, Baguley BC, Garg S (2009) Formulation and pharmacokinetic evaluation of an asulacrine nanocrystalline suspension for intravenous delivery. Int J Pharm 367: 179-186.
-
(2009)
Int J Pharm
, vol.367
, pp. 179-186
-
-
Ganta, S.1
Paxton, J.W.2
Baguley, B.C.3
Garg, S.4
-
9
-
-
41349120910
-
Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions
-
Gao L, Zhang D, Chen M, Duan C, Dai W, Jia L, Zhao W (2008) Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions. Int J Pharm 355: 321-327.
-
(2008)
Int J Pharm
, vol.355
, pp. 321-327
-
-
Gao, L.1
Zhang, D.2
Chen, M.3
Duan, C.4
Dai, W.5
Jia, L.6
Zhao, W.7
-
10
-
-
21844461846
-
Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine
-
DOI 10.1016/j.ijpharm.2005.05.014, PII S0378517305003212
-
Hecq J, Deleers M, Fanara D, Vranckx H, Amighi K (2005) Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine. Int J Pharm 299: 167-177. (Pubitemid 40962418)
-
(2005)
International Journal of Pharmaceutics
, vol.299
, Issue.1-2
, pp. 167-177
-
-
Hecq, J.1
Deleers, M.2
Fanara, D.3
Vranckx, H.4
Amighi, K.5
-
11
-
-
70349424713
-
Anti-inflammatory effects of apigenin on nicotine- And lipopolysaccharide-stimulated human periodontal ligament cells via heme oxygenase-1
-
Jeong GS, Lee SH, Jeong SN, Kim YC, Kim EC (2009) Anti-inflammatory effects of apigenin on nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via heme oxygenase-1. Int Immunopharmacol 9: 1374-1380.
-
(2009)
Int Immunopharmacol
, vol.9
, pp. 1374-1380
-
-
Jeong, G.S.1
Lee, S.H.2
Jeong, S.N.3
Kim, Y.C.4
Kim, E.C.5
-
12
-
-
33344478634
-
Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs
-
DOI 10.1016/j.jconrel.2005.11.013, PII S0168365905006565
-
Jinno J, Kamada N, Miyake M, Yamada K, Mukai T, Odomi M, Toguchi H, Liversidge GG, Higaki K, Kimura T (2006) Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs. J Control Release 111: 56-64. (Pubitemid 43289995)
-
(2006)
Journal of Controlled Release
, vol.111
, Issue.1-2
, pp. 56-64
-
-
Jinno, J.-I.1
Kamada, N.2
Miyake, M.3
Yamada, K.4
Mukai, T.5
Odomi, M.6
Toguchi, H.7
Liversidge, G.G.8
Higaki, K.9
Kimura, T.10
-
13
-
-
34447254990
-
Nanosuspension as an ophthalmic delivery system for certain glucocorticoid drugs
-
Kassem MA, Abdel Rahman AA, Ghorab MM, Ahmed MB, Khalil RM (2007) Nanosuspension as an ophthalmic delivery system for certain glucocorticoid drugs. Int J Pharm 340: 126-133.
-
(2007)
Int J Pharm
, vol.340
, pp. 126-133
-
-
Kassem, M.A.1
Abdel Rahman, A.A.2
Ghorab, M.M.3
Ahmed, M.B.4
Khalil, R.M.5
-
15
-
-
62749092217
-
NanoCrystal® Technology: A formulation approach for poorly water soluble Compounds
-
Brussels
-
Keck CM (2008) NanoCrystal® Technology: A formulation approach for poorly water soluble Compounds. Particle Design for APIs and Drug Products. Brussels.
-
(2008)
Particle Design for APIs and Drug Products
-
-
Keck, C.M.1
-
16
-
-
76149089279
-
Second generation of drug nanocrystals for delivery of poorly soluble drugs: SmartCrystal technology
-
Keck CM, Kobierski S, Mauludin R, Müller RH (2008) Second generation of drug nanocrystals for delivery of poorly soluble drugs: smartCrystal technology. Dosis 2: 124-128.
-
(2008)
Dosis
, vol.2
, pp. 124-128
-
-
Keck, C.M.1
Kobierski, S.2
Mauludin, R.3
Müller, R.H.4
-
17
-
-
41349090570
-
Size analysis of submicron particles by laser diffractometry-90% of the published measurements are false
-
Keck CM, Müller RH (2008) Size analysis of submicron particles by laser diffractometry-90% of the published measurements are false. Int J Pharm 355: 150-163.
-
(2008)
Int J Pharm
, vol.355
, pp. 150-163
-
-
Keck, C.M.1
Müller, R.H.2
-
18
-
-
78650276324
-
SmartCrystals-Review of the Second Generation of Drug Nanocrystals
-
V. P. Torchilin (ed.) London, Imperial College Press
-
Keck CM, Müller RH (2008) smartCrystals-Review of the Second Generation of Drug Nanocrystals.In: V. P. Torchilin (ed.) Nanoparticlulates as Drug Carriers. London, Imperial College Press.
-
(2008)
Nanoparticlulates As Drug Carriers
-
-
Keck, C.M.1
Müller, R.H.2
-
19
-
-
78650283578
-
Influence of different stabilizers on particle size of apigenin nanosuspensions produced by high pressure homogenization
-
Kerč J, Kobierski S, Keck CM, Müller RH (2009) Influence of different stabilizers on particle size of apigenin nanosuspensions produced by high pressure homogenization. Annual Meeting & Exposition of the Controlled Release Society, Copenhagen, Denmark.
-
(2009)
Annual Meeting & Exposition of the Controlled Release Society, Copenhagen, Denmark
-
-
Kerč, J.1
Kobierski, S.2
Keck, C.M.3
Müller, R.H.4
-
20
-
-
0031962808
-
Effects of naturally-occurring flavonoids and biflavonoids on epidermal cyclooxygenase and lipoxygenase from guinea-pigs
-
DOI 10.1016/S0952-3278(98)90125-9
-
Kim HP, Mani I, Iversen L, Ziboh VA (1998) Effects of naturally-occurring flavonoids and biflavonoids on epidermal cyclooxygenase and lipoxygenase from guinea-pigs. Prostag Leukotr Ess 58: 17-24. (Pubitemid 28053786)
-
(1998)
Prostaglandins Leukotrienes and Essential Fatty Acids
, vol.58
, Issue.1
, pp. 17-24
-
-
Kim, H.P.1
Mani, I.2
Iversen, L.3
Ziboh, V.A.4
-
21
-
-
0343831483
-
Atovaquone nanosuspensions show excellent therapeutic effect in a new murine model of reactivated toxoplasmosis
-
DOI 10.1128/AAC.45.6.1771-1779.2001
-
Krause K, Kayser O, Müller RH, Borner K, Hahn H, Liesenfeld O (2001) Atovaquone nanosuspensions show excellent therapeutic effect in a new murine model of reactivated toxoplasmosis. Antimicrob Agents Chemothes 45: 1771-1779. (Pubitemid 32466347)
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, Issue.6
, pp. 1771-1779
-
-
Scholer, N.1
Krause, K.2
Kayser, O.3
Muller, R.H.4
Borner, K.5
Hahn, H.6
Liesenfeld, O.7
-
22
-
-
67349098845
-
Diclofenac nanosuspensions: Influence of preparation procedure and crystal form on drug dissolution behaviour
-
Lai F, Sinico C, Ennas G, Marongiu F, Marongiu G, Fadda AM (2009) Diclofenac nanosuspensions: influence of preparation procedure and crystal form on drug dissolution behaviour. Int J Pharm 373: 124-132.
-
(2009)
Int J Pharm
, vol.373
, pp. 124-132
-
-
Lai, F.1
Sinico, C.2
Ennas, G.3
Marongiu, F.4
Marongiu, G.5
Fadda, A.M.6
-
24
-
-
61349095957
-
Development of an oral rutin nanocrystal formulation
-
Mauludin R, Müller RH, Keck CM (2009) Development of an oral rutin nanocrystal formulation. Int J Pharm 370: 202-209.
-
(2009)
Int J Pharm
, vol.370
, pp. 202-209
-
-
Mauludin, R.1
Müller, R.H.2
Keck, C.M.3
-
25
-
-
62749150964
-
Production and characterization of Hesperetin nanosuspensions for dermal delivery
-
Mishra PR, Al Shaal L, Müller RH, Keck CM (2009) Production and characterization of Hesperetin nanosuspensions for dermal delivery. Int J Pharm 371(1-2): 182-189.
-
(2009)
Int J Pharm
, vol.371
, Issue.1-2
, pp. 182-189
-
-
Mishra, P.R.1
Al Shaal, L.2
Müller, R.H.3
Keck, C.M.4
-
26
-
-
0033025593
-
Nanosuspensionen: Formulierungen für schwerlösliche Arzneistoffe mit geringer Bioverfügbarkeit. 2. Mitteilung: Stabilität, biopharmazeutische Aspekte, mögliche Arzneiformen und Zulassungsfragen
-
Müller RH, Böhm BHL, Grau MJ (1999) Nanosuspensionen: Formulierungen für schwerlösliche Arzneistoffe mit geringer Bioverfügbarkeit. 2. Mitteilung: Stabilität, biopharmazeutische Aspekte, mögliche Arzneiformen und Zulassungsfragen. Pharm. Ind. 61: 175-178.
-
(1999)
Pharm. Ind.
, Issue.61
, pp. 175-178
-
-
Müller, R.H.1
Böhm, B.H.L.2
Grau, M.J.3
-
27
-
-
0027370856
-
Emulsions for Intravenous Administration. I. Emulsions for nutrition and drug delivery
-
Müller RH, Heinemann S (1993a) Emulsions for Intravenous Administration. I. Emulsions for nutrition and drug delivery.Tharu 2nd 55: 853-856.
-
(1993)
Tharu 2nd
, vol.55
, pp. 853-856
-
-
Müller, R.H.1
Heinemann, S.2
-
28
-
-
0027427273
-
Emulsions for Intravenous Application. II. Destabilisation and stabilisation mechanisms in fat emulsions
-
Müller RH, Heinemann S (1993b) Emulsions for Intravenous Application. II. Destabilisation and stabilisation mechanisms in fat emulsions. Die Pharmazeutische Industrie 55: 948-953.
-
(1993)
Die Pharmazeutische Industrie
, vol.55
, pp. 948-953
-
-
Müller, R.H.1
Heinemann, S.2
-
29
-
-
0002819692
-
Nanosuspensions for the Formulation of Poorly Soluble Drugs
-
F. Nielloud and G. Marti-Mestres (ed.) Marcel Dekker
-
Müller RH, Jacobs C, Kayser O (2000) Nanosuspensions for the Formulation of Poorly Soluble Drugs.In: F. Nielloud and G. Marti-Mestres (ed.) Pharmaceutical Emulsions and Suspensions, Marcel Dekker: 383-407.
-
(2000)
Pharmaceutical Emulsions and Suspensions
, pp. 383-407
-
-
Müller, R.H.1
Jacobs, C.2
Kayser, O.3
-
30
-
-
84967407676
-
Drug nanocrystals/nanosuspensions for the delivery of poorly soluble drugs
-
V. P. Torchilin (ed.) London, Imperial College Press
-
Müller RH, Junghanns J-U (2006) Drug nanocrystals/nanosuspensions for the delivery of poorly soluble drugs.In: V. P. Torchilin (ed.) Nanoparticulates as Drug Carriers. London, Imperial College Press: 307-328.
-
(2006)
Nanoparticulates As Drug Carriers
, pp. 307-328
-
-
Müller, R.H.1
Junghanns, J.-U.2
-
32
-
-
33746929943
-
The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells
-
DOI 10.1016/j.bbrc.2006.05.198, PII S0006291X06012812
-
Perez-Vizcaino F, Bishop-Bailley D, Lodi F, Duarte J, Cogolludo A, Moreno L, Bosca L, Mitchell JA, Warner TD (2006) The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells. Biochem Biophys Res Commun 346: 919-925. (Pubitemid 44192515)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.346
, Issue.3
, pp. 919-925
-
-
Perez-Vizcaino, F.1
Bishop-Bailley, D.2
Lodi, F.3
Duarte, J.4
Cogolludo, A.5
Moreno, L.6
Bosca, L.7
Mitchell, J.A.8
Warner, T.D.9
-
34
-
-
0032400815
-
Flavonoids: Dietary occurrence and biochemical activity
-
Peterson J, Dwyer J (1998) Flavonoids: Dietary occurrence and biochemical activity. Nutrition Res 18: 1995-2018.
-
(1998)
Nutrition Res
, vol.18
, pp. 1995-2018
-
-
Peterson, J.1
Dwyer, J.2
-
35
-
-
4544383493
-
Nanosuspensions in drug delivery
-
Rabinow BE (2004) Nanosuspensions in drug delivery. Nat Rev Drug Discov 3: 785-796.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 785-796
-
-
Rabinow, B.E.1
-
37
-
-
0035002506
-
Study of antioxidant effect of apigenin, luteolin and quercetin by DNA protective method
-
Romanova D, Vachalkova A, Cipak L, Ovesna Z, Rauko P (2001) Study of antioxidant effect of apigenin, luteolin and quercetin by DNA protective method. Neoplasma 48: 104-107. (Pubitemid 32428540)
-
(2001)
Neoplasma
, vol.48
, Issue.2
, pp. 104-107
-
-
Romanova, D.1
Vachalkova, A.2
Cipak, L.3
Ovesna, Z.4
Rauko, P.5
-
38
-
-
59549097602
-
Antigenotoxic effect of apigenin against mitomycin C induced genotoxic damage in mice bone marrow cells
-
Siddique YH, AfzalM(2009) Antigenotoxic effect of apigenin against mitomycin C induced genotoxic damage in mice bone marrow cells. Food Chem Toxicol 47: 536-539.
-
(2009)
Food Chem Toxicol
, vol.47
, pp. 536-539
-
-
Siddique, Y.H.1
Afzal, M.2
-
39
-
-
34447536520
-
When poor solubility becomes an issue: From early stage to proof of concept
-
DOI 10.1016/j.ejps.2007.05.110, PII S0928098707002345
-
Stegemann S, Leveiller F, Franchi D, de Jong H, Linden H (2007) When poor solubility becomes an issue: From early stage to proof of concept. Eur J Pharm Sci 31: 249-261. (Pubitemid 47079001)
-
(2007)
European Journal of Pharmaceutical Sciences
, vol.31
, Issue.5
, pp. 249-261
-
-
Stegemann, S.1
Leveiller, F.2
Franchi, D.3
De Jong, H.4
Linden, H.5
-
40
-
-
40949138845
-
Development of ascorbyl palmitate nanocrystals applying the nanosuspension technology
-
Teeranachaideekul V, Junyaprasert VB, Souto EB, Müller RH (2008) Development of ascorbyl palmitate nanocrystals applying the nanosuspension technology. Int J Pharm 354: 227-234.
-
(2008)
Int J Pharm
, vol.354
, pp. 227-234
-
-
Teeranachaideekul, V.1
Junyaprasert, V.B.2
Souto, E.B.3
Müller, R.H.4
-
41
-
-
53949092998
-
Top-down production of drug nanocrystals: Nanosuspension stabilization, miniaturization and transformation into solid products
-
Van Eerdenbrugh B, Van den Mooter G, Augustijns P (2008) Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products. Int J Pharm 364: 64-75.
-
(2008)
Int J Pharm
, vol.364
, pp. 64-75
-
-
Van Eerdenbrugh, B.1
Van Den Mooter, G.2
Augustijns, P.3
-
42
-
-
0029921813
-
Structural aspects of antioxidant activity of flavonoids
-
VanAcker SA, vandenBerg DJ, Tromp MN, Griffioen DH, VanBennekom WP, VanderVijgh WJ, Bast A (1996) Structural aspects of antioxidant activity of flavonoids. Free Radical Bio Med 20: 331-342.
-
(1996)
Free Radical Bio Med
, vol.20
, pp. 331-342
-
-
VanAcker, S.A.1
VandenBerg, D.J.2
Tromp, M.N.3
Griffioen, D.H.4
VanBennekom, W.P.5
VanderVijgh, W.J.6
Bast, A.7
-
43
-
-
0033933197
-
Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines
-
DOI 10.1002/1098-2744(200006)28:2<102::AID-MC6>3.0.CO;2-2
-
Wang WQ, Heideman L, Chung CS, Pelling JC, Koehler KJ, Birt DF (2000) Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines. Mol Carcinogen 28: 102-110. (Pubitemid 30432478)
-
(2000)
Molecular Carcinogenesis
, vol.28
, Issue.2
, pp. 102-110
-
-
Wang, W.1
Heideman, L.2
Chung, C.S.3
Pelling, J.C.4
Koehler, K.J.5
Birt, D.F.6
-
44
-
-
40649126076
-
Antidepressant-like behavioral and neurochemical effects of the citrus-associated chemical apigenin
-
Yi LT, Li JM, Li YC, Pan Y, Xu Q, Kong LD (2008) Antidepressant-like behavioral and neurochemical effects of the citrus-associated chemical apigenin. Life Sci 82: 741-751.
-
(2008)
Life Sci
, vol.82
, pp. 741-751
-
-
Yi, L.T.1
Li, J.M.2
Li, Y.C.3
Pan, Y.4
Xu, Q.5
Kong, L.D.6
-
45
-
-
0033004673
-
Growth inhibitory effects of flavonoids in human thyroid cancer cell lines
-
Yin F, Giuliano AE, Van Herle AJ (1999) Growth inhibitory effects of flavonoids in human thyroid cancer cell lines. Thyroid 9: 369-376.
-
(1999)
Thyroid
, vol.9
, pp. 369-376
-
-
Yin, F.1
Giuliano, A.E.2
Van Herle, A.J.3
|