A facile enantioselective synthesis of (S)-N-(5-chlorothiophene-2-sulfonyl) -β,β-diethylalaninol via proline-catalyzed asymmetric α-aminooxylation and α-amination of aldehyde

Tetrahedron Letters

Volumn 51, Issue 50, 2010, Pages 6565-6567

  Rawat, Varun ^a   Chouthaiwale, Pandurang V ^a   Chavan, Vilas B ^a   Suryavanshi, Gurunath ^a   Sudalai, Arumugam ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

Alzheimer's disease; Amino alcohol; Proline; amination; aminooxylation

Indexed keywords

3 PENTANONE; ALDEHYDE; ALICYCLIC COMPOUND; AMYLOID BETA PROTEIN; GAMMA SECRETASE INHIBITOR; N (5 CHLOROTHIOPHENE 2 SULFONYL) BETA,BETA DIETHYLALANINOL; NOTCH1 RECEPTOR; PROLINE DERIVATIVE; UNCLASSIFIED DRUG;

AMINATION; AMINOOXYLATION; ARTICLE; CATALYSIS; CHEMICAL MODIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOSELECTIVITY;

EID: 78650232831     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.10.029     Document Type: Article

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