Seroconversion to islet autoantibodies between early pregnancy and delivery in non-diabetic mothers

Journal of Reproductive Immunology

Volumn 88, Issue 1, 2011, Pages 72-79

  Lindehammer, Sabina Resic ^a   Hansson, Ida ^a   Midberg, Bo ^a   Ivarsson, Sten Anders ^a   Lynch, Kristian Francis ^a   Dillner, Joakim ^a   Lernmark, Åke ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Autoimmunity; Glutamic acid decarboxylase autoantibody; Insulin autoantibody; Islet antigen 2 autoantibody; Pregnancy; Seroconversion

Indexed keywords

AUTOANTIBODY; GLUTAMIC ACID DECARBOXYLASE AUTOANTIBODY; INSULIN AUTOANTIBODY; ISLET ANTIGEN 2 AUTOANTIBODY; UNCLASSIFIED DRUG;

ADULT; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DELIVERY; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; PARITY; PRIORITY JOURNAL; SEROCONVERSION;

AUTOANTIBODIES; DIABETES MELLITUS, TYPE 1; FEMALE; FETAL BLOOD; GESTATIONAL AGE; GLUTAMATE DECARBOXYLASE; HUMANS; INSULIN; INSULIN ANTIBODIES; ISLETS OF LANGERHANS; PARTURITION; PREGNANCY; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 8;

EID: 78650228451     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2010.10.002     Document Type: Article

References (38)

1. ADA Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003, 26(Suppl. 1):S5-S20.
2. Alberti K.G., Zimmet P.Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1. Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet. Med. 1998, 15:539-553.
3. Maternal, Fetal, and Neonatal Physiology 1992, W.B. Saunders Co., Philadelphia. S.T. Blackburn, D.L. Loper (Eds.).
4. Borg H., Gottsater A., Fernlund P., Sundkvist G. A 12-year prospective study of the relationship between islet antibodies and beta-cell function at and after the diagnosis in patients with adult-onset diabetes. Diabetes 2002, 51:1754-1762.
5. Maternal Cardiovascular and Renal Disorders-Biologic Adaptation to Pregnancy 1984, Saunders, Philadelphia. C.R. Brinkman (Ed.).
6. Campbell D.M., Macgillivray I. Comparison of maternal response in first and second pregnancies in relation to baby weight. J. Obstet. Gynaecol. Br. Commonw. 1972, 79:684-693.
7. Chesley L.C. Plasma and red cell volumes during pregnancy. Am. J. Obstet. Gynecol. 1972, 112:440-450.
8. D'armiento M., Salabe H., Vetrano G., Scucchia M., Pachi A. Decrease of thyroid antibodies during pregnancy. J. Endocrinol. Invest. 1980, 3:437-438.
9. Dagher F.J., Lyons J.H., Finlayson D.C., Shamsai J., Moore F.D. Blood volume measurement: a critical study prediction of normal values: controlled measurement of sequential changes: choice of a bedside method. Adv. Surg. 1965, 1:69-109.
10. Dahlquist G., Kallen B. Maternal-child blood group incompatibility and other perinatal events increase the risk for early-onset type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1992, 35:671-675.
11. Dahlquist G.G., Ivarsson S., Lindberg B., Forsgren M. Maternal enteroviral infection during pregnancy as a risk factor for childhood IDDM. A population-based case-control study. Diabetes 1995, 44:408-413.
12. El-Roeiy A., Shoenfeld Y. Autoimmunity and pregnancy. Am. J. Reprod. Immunol. Microbiol. 1985, 9:25-32.
13. Elfving M., Lindberg B., Lynch K., Mansson M., Sundkvist G., Lernmark A., Ivarsson S.A. Number of islet autoantibodies present in newly diagnosed type 1 diabetes children born to non-diabetic mothers is affected by islet autoantibodies present at birth. Pediatr. Diabetes 2008, 9:127-134.
14. Falorni A., Ortqvist E., Persson B., Lernmark A. Radioimmunoassays for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands. J. Immunol. Methods 1995, 186:89-99.
15. Hamalainen A.M., Savola K., Kulmala P.K., Koskela P., Akerblom H.K., Knip M. Disease-associated autoantibodies during pregnancy and at birth in families affected by type 1 diabetes. Clin. Exp. Immunol. 2001, 126:230-235.
16. Helgason T., Jonasson M.R. Evidence for a food additive as a cause of ketosis-prone diabetes. Lancet 1981, 2:716-720.
17. Hyoty H., Hiltunen M., Knip M., Laakkonen M., Vahasalo P., Karjalainen J., Koskela P., Roivainen M., Leinikki P., Hovi T., et al. A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM. Diabetes 1995, 44:652-657. Childhood Diabetes in Finland (DiMe) Study Group.
18. Hytten F.E., Paintin D.B. Increase in plasma volume during normal pregnancy. J. Obstet. Gynaecol. Br. Emp. 1963, 70:402-407.
19. Ivarsson S.A., Ackefors M., Carlsson A., Ekberg G., Falorni A., Kockum I., Landin-Olsson M., Lernmark A., Lindberg B., Sundkvist G., Svanberg L. Glutamate decarboxylase antibodies in non-diabetic pregnancy precedes insulin-dependent diabetes in the mother but not necessarily in the offspring. Autoimmunity 1997, 26:261-269.
20. Jones M.E., Swerdlow A.J., Gill L.E., Goldacre M.J. Pre-natal and early life risk factors for childhood onset diabetes mellitus: a record linkage study. Int. J. Epidemiol. 1998, 27:444-449.
21. Koczwara K., Bonifacio E., Ziegler A.G. Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes. Diabetes 2004, 53:1-4.
22. Larsson H.E., Lynch K., Lernmark B., Nilsson A., Hansson G., Almgren P., Lernmark A., Ivarsson S.A. Diabetes-associated HLA genotypes affect birthweight in the general population. Diabetologia 2005, 48:1484-1491.
23. Lernmark B., Elding-Larsson H., Hansson G., Lindberg B., Lynch K., Sjoblad S. Parent responses to participation in genetic screening for diabetes risk. Pediatr. Diabetes 2004, 5:174-181.
24. Levy D.L. Fetal-neonatal involvement in maternal autoimmune disease. Obstet. Gynecol. Surv. 1982, 37:122-127.
25. Lindberg B., Ivarsson S.A., Landin-Olsson M., Sundkvist G., Svanberg L., Lernmark A. Islet autoantibodies in cord blood from children who developed type I (insulin-dependent) diabetes mellitus before 15 years of age. Diabetologia 1999, 42:181-187.
26. Lynch K.F., Lernmark B., Merlo J., Cilio C.M., Ivarsson S.A., Lernmark A. Cord blood islet autoantibodies and seasonal association with the type 1 diabetes high-risk genotype. J. Perinatol. 2008, 28:211-217.
27. Novak E.J., Ortqvist E., Nord E., Edwall L., Hampe C.S., Bekris L., Persson B.E., Lernmark A. Stability of disease-associated antibody titers in pregnant women with type 1 diabetes with or without residual beta-cell function. Diabetes Care 2000, 23:1019-1021.
28. Peck T.M., Arias F. Hematologic changes associated with pregnancy. Clin. Obstet. Gynecol. 1979, 22:785-798.
29. Pirani B.B., Campbell D.M., Macgillivray I. Plasma volume in normal first pregnancy. J. Obstet. Gynaecol. Br. Commonw. 1973, 80:884-887.
30. Pritchard J.A. Changes in the blood volume during pregnancy and delivery. Anesthesiology 1965, 26:393-399.
31. Ryding J., French K.M., Naucler P., Barnabas R.V., Garnett G.P., Dillner J. Seroepidemiology as basis for design of a human papillomavirus vaccination program. Vaccine 2008, 26:5263-5268.
32. Schindler A.E. Immunology and progestins in pregnancy. Gynecol. Endocrinol. 1999, 13(Suppl. 4):47-50.
33. Stene L.C., Magnus P., Lie R.T., Sovik O., Joner G. No association between preeclampsia or cesarean section and incidence of type 1 diabetes among children: a large, population-based cohort study. Pediatr. Res. 2003, 54:487-490.
34. Torn C., Mueller P.W., Schlosser M., Bonifacio E., Bingley P.J. Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2. Diabetologia 2008, 51:846-852.
35. Wilder R.L. Hormones, pregnancy, and autoimmune diseases. Ann. N.Y. Acad. Sci. 1998, 840:45-50.
36. Williams A.J., Bingley P.J., Bonifacio E., Palmer J.P., Gale E.A. A novel micro-assay for insulin autoantibodies. J. Autoimmun. 1997, 10:473-478.
37. Viskari H.R., Roivainen M., Reunanen A., Pitkaniemi J., Sadeharju K., Koskela P., Hovi T., Leinikki P., Vilja P., Tuomilehto J., Hyoty H. Maternal first-trimester enterovirus infection and future risk of type 1 diabetes in the exposed fetus. Diabetes 2002, 51:2568-2571.
38. Wyle F.A., Kent J.R. Immunosuppression by sex steroid hormones. The effect upon PHA- and PPD-stimulated lymphocytes. Clin. Exp. Immunol. 1977, 27:407-415.