Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite

Journal of Pharmaceutical and Biomedical Analysis

Volumn 54, Issue 2, 2011, Pages 359-367

  Déglon, Julien ^a,c   Thomas, Aurélien ^a,c   Daali, Youssef ^b,c   Lauer, Estelle ^a   Samer, Caroline ^b,c   Desmeules, Jules ^b,c   Dayer, Pierre ^b,c   Mangin, Patrice ^a   Staub, Christian ^a,c  

^a UNIVERSITY CENTER OF LEGAL MEDICINE   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Automated system; Flurbiprofen; LC MS MS; On line DBS; Pharmacokinetic

Indexed keywords

4 HYDROXYFLURBIPROFEN; DRUG METABOLITE; FLURBIPROFEN; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; DRUG BLOOD LEVEL; ENVIRONMENTAL TEMPERATURE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; NORMAL HUMAN; ON LINE DESORPTION OF DRIED BLOOD SPOTS AUTOMATED SYSTEM; PLASMA; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ADSORPTION; BLOOD CHEMICAL ANALYSIS; CALIBRATION; CHROMATOGRAPHY, LIQUID; DESICCATION; DRUG STABILITY; DRUG STORAGE; FLURBIPROFEN; GUIDELINES AS TOPIC; HUMANS; MALE; MICROPORE FILTERS; ONLINE SYSTEMS; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECIMEN HANDLING; TABLETS; TANDEM MASS SPECTROMETRY;

EID: 78650224598     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.08.032     Document Type: Article

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