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Volumn 9, Issue 1, 2011, Pages 49-56

Caffeine-suppressed ATM pathway leads to decreased p53 phosphorylation and increased programmed cell death in gamma-irradiated leukaemic molt-4 cells

Author keywords

ATM; Caffeine; Ionising radiation; Mcl 1; MOLT 4; P21; P53

Indexed keywords

ATM PROTEIN; BETA ACTIN; CAFFEINE; LIPOCORTIN 5; PROPIDIUM IODIDE; PROTEIN KINASE; PROTEIN MCL 1; PROTEIN P21; PROTEIN P53; SERINE;

EID: 78650181755     PISSN: 1214021X     EISSN: 12140287     Source Type: Journal    
DOI: 10.2478/v10136-009-0031-7     Document Type: Article
Times cited : (9)

References (37)
  • 1
    • 0034706917 scopus 로고    scopus 로고
    • Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: Reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants
    • Asaad NA, Zeng ZC, Guan J, Thacker J, Iliakis G. Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants. Oncogene. 19: 5788-5800, 2000.
    • (2000) Oncogene , vol.19 , pp. 5788-5800
    • Asaad, N.A.1    Zeng, Z.C.2    Guan, J.3    Thacker, J.4    Iliakis, G.5
  • 2
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimmer dissociation
    • Bakkenist C, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimmer dissociation. Nature. 421: 499-506, 2003.
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.1    Kastan, M.B.2
  • 3
    • 0035895622 scopus 로고    scopus 로고
    • Pathways governing G1/S transition and their response to DNA damage
    • Bartek J, Lukas J. Pathways governing G1/S transition and their response to DNA damage. FEBS Lett. 490: 117-122, 2001.
    • (2001) FEBS Lett , vol.490 , pp. 117-122
    • Bartek, J.1    Lukas, J.2
  • 5
    • 3042838562 scopus 로고    scopus 로고
    • Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine
    • Block WD, Merkle D, Meek K, Lees-Miller SP. Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine. Nucl Acids Res. 32: 1967-1972, 2004.
    • (2004) Nucl Acids Res , vol.32 , pp. 1967-1972
    • Block, W.D.1    Merkle, D.2    Meek, K.3    Lees-Miller, S.P.4
  • 6
    • 0037213368 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions
    • Borner C. The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions. Mol Immunol. 39: 615-647, 2003.
    • (2003) Mol Immunol , vol.39 , pp. 615-647
    • Borner, C.1
  • 8
    • 0141621266 scopus 로고    scopus 로고
    • Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasiamutated (ATM) and ATM- and Rad3-related (ATR) protein kinases
    • Cortez D. Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasiamutated (ATM) and ATM- and Rad3-related (ATR) protein kinases. J Biol Chem. 278: 37139-37145, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 37139-37145
    • Cortez, D.1
  • 9
    • 0141645610 scopus 로고    scopus 로고
    • Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation
    • Criswell T, Leskov K, Miyamoto S, Luo G, Boothman DA. Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation. Oncogene. 22: 5813-5827, 2003.
    • (2003) Oncogene , vol.22 , pp. 5813-5827
    • Criswell, T.1    Leskov, K.2    Miyamoto, S.3    Luo, G.4    Boothman, D.A.5
  • 10
    • 0035501562 scopus 로고    scopus 로고
    • Caffeine and the G2/M block override: A concept resulting from a misleading cell kinetic delay, independent of functional p53
    • Deplanque G, Céraline J, Mah-Becherel MC, Cazenave JP, Bergerat JP, Klein-Soyer C. Caffeine and the G2/M block override: A concept resulting from a misleading cell kinetic delay, independent of functional p53. Int J Cancer. 94: 363-369, 2001.
    • (2001) Int J Cancer , vol.94 , pp. 363-369
    • Deplanque, G.1    Céraline, J.2    Mah-Becherel, M.C.3    Cazenave, J.P.4    Bergerat, J.P.5    Klein-Soyer, C.6
  • 11
    • 34548027992 scopus 로고    scopus 로고
    • Timing of apoptosis onset depends on cell cycle progression in peripheral blood lymphocytes and lymphocytic leukemia cells
    • Feng Y, Wu J, Feng X, Tao D, Hu J, Qin J, Li X, Xiao W, Gardner K, Judge SIV, Li QQ, Gong J. Timing of apoptosis onset depends on cell cycle progression in peripheral blood lymphocytes and lymphocytic leukemia cells. Oncol Rep. 17: 1437-1444, 2007.
    • (2007) Oncol Rep , vol.17 , pp. 1437-1444
    • Feng, Y.1    Wu, J.2    Feng, X.3    Tao, D.4    Hu, J.5    Qin, J.6    Li, X.7    Xiao, W.8    Gardner, K.9    Judge, S.I.V.10    Li, Q.Q.11    Gong, J.12
  • 12
    • 12544250589 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage
    • Helt CE, Cliby WA, Keng PC, Bambara RA, O'Reilly MA. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage. J Biol Chem. 280: 1186-1192, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 1186-1192
    • Helt, C.E.1    Cliby, W.A.2    Keng, P.C.3    Bambara, R.A.4    O'Reilly, M.A.5
  • 13
    • 48149095219 scopus 로고    scopus 로고
    • Chromium-mediated apoptosis: Involvement of DNA-dependent protein kinase (DNA-PK) and differential induction of p53 target genes
    • Hill R, Leidal AM, Madureira PA, Gillis LD, Waisman DM, Chiu A, Lee PW. Chromium-mediated apoptosis: involvement of DNA-dependent protein kinase (DNA-PK) and differential induction of p53 target genes. DNA Repair (Amst). 7: 1484-1499, 2008.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1484-1499
    • Hill, R.1    Leidal, A.M.2    Madureira, P.A.3    Gillis, L.D.4    Waisman, D.M.5    Chiu, A.6    Lee, P.W.7
  • 14
    • 0030977349 scopus 로고    scopus 로고
    • Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family
    • Hoekstra MF. Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family. Curr Opin Genet Dev. 7: 170-175, 1997.
    • (1997) Curr Opin Genet Dev , vol.7 , pp. 170-175
    • Hoekstra, M.F.1
  • 19
    • 0030933152 scopus 로고    scopus 로고
    • The genetic defect in ataxia-telangiectasia
    • Lavin MF, Shiloh Y. The genetic defect in ataxia-telangiectasia. Annu Rev Immunol. 15: 177-202, 1997.
    • (1997) Annu Rev Immunol , vol.15 , pp. 177-202
    • Lavin, M.F.1    Shiloh, Y.2
  • 23
    • 65249117412 scopus 로고    scopus 로고
    • Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway
    • Meng AG, Jiang LL. Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway. Acta Pharmacol Sin. 30: 442-450, 2009.
    • (2009) Acta Pharmacol Sin , vol.30 , pp. 442-450
    • Meng, A.G.1    Jiang, L.L.2
  • 24
    • 1842515632 scopus 로고    scopus 로고
    • A multifaceted role for ATM in genome maintenance
    • Pandita TK. A multifaceted role for ATM in genome maintenance. Exp Rev Mol Med. 5: 1-21, 2003.
    • (2003) Exp Rev Mol Med , vol.5 , pp. 1-21
    • Pandita, T.K.1
  • 25
    • 53249144290 scopus 로고    scopus 로고
    • Modulation of cellular response to anticancer treatment by caffeine: Inhibition of cell cycle checkpoints, DNA repair and more
    • Sabisz M, Skladanowski A. Modulation of cellular response to anticancer treatment by caffeine: inhibition of cell cycle checkpoints, DNA repair and more. Curr Pharm Biotechnol. 9: 325-336, 2008.
    • (2008) Curr Pharm Biotechnol , vol.9 , pp. 325-336
    • Sabisz, M.1    Skladanowski, A.2
  • 29
    • 0036490992 scopus 로고    scopus 로고
    • CDK inhibitors: Cell cycle arrest versus apoptosis
    • Schwartz GK. CDK inhibitors: cell cycle arrest versus apoptosis. Cell Cycle. 1: 122-123, 2002.
    • (2002) Cell Cycle , vol.1 , pp. 122-123
    • Schwartz, G.K.1
  • 30
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • Shieh SY, Ikeda M, Taya Y, Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell. 91: 325-334, 1997.
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 32
    • 0025954652 scopus 로고
    • Chemically induced premature mitosis: Differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation
    • 6843-6837
    • Steinmann KE, Belinsky GS, Lee D, Schlegel R. Chemically induced premature mitosis: differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation. Proc Natl Acad Sci USA. 88: 6843-6837, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88
    • Steinmann, K.E.1    Belinsky, G.S.2    Lee, D.3    Schlegel, R.4
  • 35
    • 45849114070 scopus 로고    scopus 로고
    • Gamma irradiation of human leukaemic cells HL-60 and MOLT-4 induces decrease in Mcl-1 and Bid, release of cytochrome c, and activation of caspase-8 and caspase-9
    • Tichý A, Záškodová D, Pejchal J, Řezáčová M, Österreicher J, Vávrová J, Cerman J. Gamma irradiation of human leukaemic cells HL-60 and MOLT-4 induces decrease in Mcl-1 and Bid, release of cytochrome c, and activation of caspase-8 and caspase-9. Int J Radiat Biol. 84: 523-530, 2008.
    • (2008) Int J Radiat Biol , vol.84 , pp. 523-530
    • Tichý, A.1    Záškodová, D.2    Pejchal, J.3    Řezáčová, M.4    Österreicher, J.5    Vávrová, J.6    Cerman, J.7
  • 36
  • 37
    • 17344392896 scopus 로고    scopus 로고
    • Cell cycle alteration, apoptosis and response of leukemic cell lines to gamma radiation with highand low-dose rate
    • Vávrová J, Řezáčová M, Vokurková D, Psutka J. Cell cycle alteration, apoptosis and response of leukemic cell lines to gamma radiation with highand low-dose rate. Physiol Res. 53: 335-342, 2004.
    • (2004) Physiol Res , vol.53 , pp. 335-342
    • Vávrová, J.1    Řezáčová, M.2    Vokurková, D.3    Psutka, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.