QSAR studies of imidazopyridine derivatives as Et-PKG inhibitors using the PSO-SVM approach

Medicinal Chemistry Research

Volumn 19, Issue 9, 2010, Pages 1307-1325

  Cheng, Zhengjun ^a   Zhang, Yuntao ^a   Zhang, Wenjun ^a  

^a CHINA WEST NORMAL UNIVERSITY   (China)

Author keywords

Imidazopyridine derivatives; Particle swarm optimization; Quantitative structure activity relationship; Support vector machine; Two dimensional (2D) autocorrelation descriptor

Indexed keywords

CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; IMIDAZOPYRIDINE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CORRELATION COEFFICIENT; DRUG ACTIVITY; ENZYME INHIBITION; MOLECULAR MODEL; MULTIPLE LINEAR REGRESSION ANALYSIS; PREDICTIVE VALIDITY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SPATIAL AUTOCORRELATION ANALYSIS; STRUCTURE ACTIVITY RELATION; SUPPORT VECTOR MACHINE;

EID: 78650173327     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-009-9272-y     Document Type: Article

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