Progressive loss of synaptic integrity in human apolipoprotein E4 targeted replacement mice and attenuation by apolipoprotein E2

Neuroscience

Volumn 171, Issue 4, 2010, Pages 1265-1272

  Klein, R C ^a,b   Mace, B E ^a,b   Moore, S D ^a,b   Sullivan, P M ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DURHAM VA MEDICAL CENTER   (United States)

Author keywords

APOE; Integrity; Mice; Replacement; Synaptic; Targeted

Indexed keywords

APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4;

AGE; AGE DISTRIBUTION; AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; C57BL 6 MOUSE; CONTROLLED STUDY; DENDRITIC CELL; EXCITATORY POSTSYNAPTIC POTENTIAL; GENOTYPE; HETEROZYGOSITY; KNOCKOUT MOUSE; MORPHOMETRICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION;

AGE FACTORS; AMYGDALA; ANIMALS; APOLIPOPROTEIN E2; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; EXCITATORY POSTSYNAPTIC POTENTIALS; GENOTYPE; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; PATCH-CLAMP TECHNIQUES; SINGLE-BLIND METHOD; SYNAPSES;

EID: 78650169584     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.10.027     Document Type: Article

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