A real-time screening assay for GIRK1/4 channel blockers

Journal of Biomolecular Screening

Volumn 15, Issue 10, 2010, Pages 1229-1237

  Walsh, Kenneth B ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

atrial fibrillation; cardiac cell line; drug screening; FLIPR; GIRK1 4 channel

Indexed keywords

1 (1 PIPERIDINYL) 3 (4 PROPYLPHENOXY) 2 PROPANOL; 1 [2 [2 (DIETHYLAMINO)ETHOXY]PHENYL] 3 PHENYL 1 PROPANONE; 1 [2 [2 HYDROXY 3 (1 PIPERIDINYL)PROPOXY]PHENYL] 3 PHENYL 1 PROPANONE; 1 [2 [2 HYDROXY 3 (4 MORPHOLINYL)PROPOXY]PHENYL] 3 PHENYL 1 PROPANONE; 1 [2 [3 (DIETHYLAMINO) 2 HYDROXYPROPOXY]PHENYL] 3 PHENYL 1 PROPANONE; 1 [2 [3 (ETHYLAMINO) 2 HYDROXYPROPOXY]PHENYL]ETHANONE; 1 [2 [3 (TERT BUTYLAMINO) 2 HYDROXYPROPOXY]PHENYL] 3 PHENYL 1 PROPANONE; 5 (N ETHYL N ISOPROPYL)AMILORIDE; 5 HYDROXYPROPAFENONE; AMILORIDE DERIVATIVE; BARBITURIC ACID DERIVATIVE; BARIUM CHLORIDE; CARBACHOL; FLECAINIDE; FLUORESCENT DYE; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 1; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 1 BLOCKER; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 4; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 4 BLOCKER; GLIBENCLAMIDE; IBUTILIDE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; PROCAINAMIDE; PROPAFENONE; PROPAFENONE DERIVATIVE; QUINIDINE; SOTALOL; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CELL MEMBRANE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SCREENING; HEART ATRIUM FIBRILLATION; MOUSE; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL;

ACETYLCHOLINE; AMILORIDE; ANIMALS; ATRIAL FIBRILLATION; BARBITURATES; BIOLOGICAL ASSAY; BIOLOGICAL TRANSPORT; CARBACHOL; CELL LINE; DRUG DISCOVERY; FLUORESCENT DYES; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HEART ATRIA; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; ISOXAZOLES; MEMBRANE POTENTIALS; MICE; PATCH-CLAMP TECHNIQUES; PROPAFENONE; SMALL MOLECULE LIBRARIES;

EID: 78650164913     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110381384     Document Type: Article

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