Rab7 mutants associated with charcot-Marie-tooth disease exhibit enhanced NGF-stimulated signaling

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Basuray, Soumik ^a   Mukherjee, Sanchita ^a,b   Romero, Elsa ^a   Wilson, Michael C ^a   Wandinger Ness, Angela ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MUTANT PROTEIN; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; PHOSPHATASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE A; RAB7 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; RAB PROTEIN;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL MEMBRANE; CELL STRAIN; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEREDITARY MOTOR SENSORY NEUROPATHY; MISSENSE MUTATION; NERVE CELL; NERVE FIBER GROWTH; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; CELL FRACTIONATION; CONFOCAL MICROSCOPY; GENETICS; METABOLISM; METHODOLOGY; MUTATION; PHOSPHORYLATION; RAT;

ANIMALS; CELL MEMBRANE; CHARCOT-MARIE-TOOTH DISEASE; ENDOSOMES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MICROSCOPY, CONFOCAL; MUTATION; NERVE GROWTH FACTOR; PC12 CELLS; PHOSPHORYLATION; RAB GTP-BINDING PROTEINS; RATS; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS;

EID: 78650130133     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015351     Document Type: Article

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