Interferon-γ decreases chondroitin sulfate proteoglycan expression and enhances hindlimb function after spinal cord injury in mice

Journal of Neurotrauma

Volumn 27, Issue 12, 2010, Pages 2283-2294

  Fujiyoshi, Takayuki ^a   Kubo, Takekazu ^a   Chan, Carmen C M ^a   Koda, Masao ^a   Okawa, Akihiko ^a   Takahashi, Kazuhisa ^a   Yamazaki, Masashi ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

astrocyte; chondroitin sulfate proteoglycan; interferon ; macrophage; microglia; neurotrophic factors; spinal cord injury

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NEUROCAN; PROTEOCHONDROITIN SULFATE; RECOMBINANT GAMMA INTERFERON; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BIOACCUMULATION; CELL FUNCTION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME INDUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLIA CELL; HINDLIMB; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MACROPHAGE; MALE; MOUSE; MYELINATED NERVE; NERVE FIBER GROWTH; NEUROMODULATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD INJURY; TREATMENT OUTCOME; UPREGULATION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CELLS, CULTURED; CHONDROITIN SULFATE PROTEOGLYCANS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HINDLIMB; IMMUNOHISTOCHEMISTRY; INTERFERON-GAMMA; MICE; MICROGLIA; MOTOR ACTIVITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPINAL CORD; SPINAL CORD INJURIES;

EID: 78650129733     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2009.1144     Document Type: Article

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