A systems biology analysis of metastatic melanoma using in-depth three-dimensional protein profiling

Proteomics

Volumn 10, Issue 24, 2010, Pages 4450-4462

  Han, Mee Jung ^a,b   Wang, Huan ^a   Beer, Lynn A ^a   Tang, Hsin Yao ^a   Herlyn, Meenhard ^a   Speicher, David W ^a  

^a WISTAR INSTITUTE   (United States)

^b Dongyang University   (South Korea)

Author keywords

2 D DIGE; Metastatic melanoma; Microscale solution IEF; Protein networks; Systems biology

Indexed keywords

2 METHOXYESTRADIOL; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ACTIN; CALVASCULIN; CASPASE; CATHEPSIN B; CATHEPSIN D; CD9 ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GALECTIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; INTERLEUKIN 1; INTERLEUKIN 1BETA; LAMIN B; LIM KINASE 1; MYC PROTEIN; NUCLEOPHOSMIN; PEROXIREDOXIN 1; PEROXIREDOXIN 2; PEROXIREDOXIN 4; PROTEIN C MYB; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR PBX1; TRANSFORMING GROWTH FACTOR BETA; TUMOR MARKER; UBIQUITIN; UNINDEXED DRUG;

ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL DEATH; CELL FRACTIONATION; CELL LYSATE; FLUORESCENCE; FUNCTIONAL PROTEOMICS; HUMAN; HUMAN CELL; MELANOMA CELL; METASTASIS POTENTIAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; THREE DIMENSIONAL IMAGING; VALIDATION STUDY;

ANIMALS; GENE REGULATORY NETWORKS; HUMANS; MELANOMA; METABOLIC NETWORKS AND PATHWAYS; MICE; PROTEOME; SKIN NEOPLASMS; SYSTEMS BIOLOGY; TUMOR CELLS, CULTURED;

EID: 78650066150     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200900549     Document Type: Article

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