Effect of dose on the biodistribution and pharmacokinetics of PLGA and PLGA-mPEG nanoparticles

International Journal of Pharmaceutics

Volumn 221, Issue 1-2, 2001, Pages 143-152

  Panagi, Z ^a   Beletsi, A ^a   Evangelatos, Gregory ^b   Livaniou, E ^b   Ithakissios, D S ^a   Avgoustakis, K ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

Author keywords

Biodistribution; Effect of dose; Pharmacokinetics; Poly(Lactide co glycolide); Poly(Lactide co glycolide) monomethoxy (polyethyleneglycol)

Indexed keywords

ANILINE DERIVATIVE; CHOLESTERYLANILINE; ETHYLENE GLYCOL DERIVATIVE; IODINE 125; NANOPARTICLE; POLY(LACTIDE GLYCOLIDE) MONOMETHOXYPOLY(ETHYLENEGLYCOL); POLYGLACTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG STABILITY; DRUG TARGETING; FEMALE; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; PLASMA CLEARANCE; POLYMERIZATION; PRECIPITATION; PRIORITY JOURNAL; RADIOACTIVITY; TISSUE DISTRIBUTION;

ANIMALS; AREA UNDER CURVE; BIOCOMPATIBLE MATERIALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HALF-LIFE; INJECTIONS, INTRAVENOUS; LACTIC ACID; METABOLIC CLEARANCE RATE; MICE; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLACTIN 910; POLYGLYCOLIC ACID; POLYMERS; TISSUE DISTRIBUTION;

EID: 0035912958     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00676-7     Document Type: Article

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