Quick and simple detection technique to assess the binding of antimicrotubule agents to the colchicine-binding site

Biological Procedures Online

Volumn 12, Issue 1, 2010, Pages 113-117

  Fortin, Sébastien ^a,b   Lacroix, Jacques ^a   Côté, Marie France ^a   Moreau, Emmanuel ^b,c   Petitclerc, Éric ^a   Gaudreault, René C ^a  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

^c UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

Antimicrotubule agent; Colchicine binding site inhibitor; EBI; N N' ethylene bis(iodoacetamide); Taxol binding site inhibitor; Tubulin affinity assay

Indexed keywords

ALPHA TUBULIN; ANTIMICROTUBULE AGENT; ANTINEOPLASTIC AGENT; BETA TUBULIN; COLCHICINE; COMBRETASTATIN A4; CYSTEINE; DAUNORUBICIN; HETERODIMER; IODOACETAMIDE; N,N' ETHYLENE BIS(IODOACETAMIDE); PODOPHYLLOTOXIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; PROTEIN ANALYSIS; PROTEIN CROSS LINKING; SECONDARY IMMUNE RESPONSE; WESTERN BLOTTING;

EID: 78649874504     PISSN: 14809222     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12575-010-9029-5     Document Type: Article

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