Microtubule disruption induced in vivo by alkylation of β-tubulin by 1- aryl-3-(2-chloroethyl)ureas, a novel class of soft alkylating agents

Cancer Research

Volumn 60, Issue 4, 2000, Pages 985-992

  Legault, Jean ^a   Gaulin, Jean François ^a   Mounetou, Emmanuelle ^a   Bolduc, Sébastien ^a   Lacroix, Jacques ^a   Poyet, Patrick ^a   C Gaudreault, René ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; BETA TUBULIN; COLCHICINE; IODOACETAMIDE; PACLITAXEL; UREA DERIVATIVE; VINBLASTINE;

ALKYLATION; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYTOTOXICITY; DEPOLYMERIZATION; DRUG COMPETITION; DRUG EFFECT; DRUG MECHANISM; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

ALKYLATION; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL CYCLE; CHO CELLS; CRICETINAE; CYSTEINE; HUMANS; MICROTUBULES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 0034652719     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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