Higher susceptibility to aflatoxin B1-related hepatocellular carcinoma in glycine N-methyltransferase knockout mice

International Journal of Cancer

Volumn 128, Issue 3, 2011, Pages 511-523

  Liu, Shih Ping ^a,b   Li, Ying Shiuan ^a   Lee, Cheng Ming ^a   Yen, Chia Hung ^a   Liao, Yi Jen ^a   Huang, Shiu Feng ^c   Chien, Chau Heng ^a   Chen, Yi Ming Arthur ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

aflatoxin B1; detoxification; gender disparity; gene knockout mice; GNMT; hepatocarcinogenesis

Indexed keywords

AFLATOXIN B1; CARRIER PROTEIN; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2D22; CYTOCHROME P450 3A44; GLUTATHIONE TRANSFERASE A4; GLYCINE METHYLTRANSFERASE; PROTEIN ABCA8A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RESISTANCE; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DETOXIFICATION; DNA ADDUCT; DOWN REGULATION; DYSPLASIA; ECHOGRAPHY; ENZYME DEFICIENCY; FEMALE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HISTOPATHOLOGY; KNOCKOUT MOUSE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER NODULE; LIVER PARENCHYMA; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; SEX DIFFERENCE; SIGNAL TRANSDUCTION; WILD TYPE;

AFLATOXIN B1; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; AUTOPSY; CARCINOMA, HEPATOCELLULAR; CROSSES, GENETIC; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUTATHIONE TRANSFERASE; GLYCINE N-METHYLTRANSFERASE; HETEROZYGOTE DETECTION; LIVER; MALE; MICE; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC;

EID: 78649831564     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25386     Document Type: Article

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