Silencing of glutathione S-transferase P1 by promoter hypermethylation and its relationship to environmental chemical carcinogens in hepatocellular carcinoma

Cancer Letters

Volumn 221, Issue 2, 2005, Pages 135-143

  Zhang, Yu Jing ^a   Chen, Yu ^a   Ahsan, Habibul ^a   Lunn, Ruth M ^b   Chen, Shu Yuan ^c   Lee, Po Huang ^d   Chen, Chien Jen ^c   Santella, Regina M ^a  

^a Columbia University ^*  (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Chemical carcinogens; Epigenetic changes; Glutathione S transferase P1; Hepatocellular carcinoma; Hypermethylation

Indexed keywords

AFLATOXIN B1; DNA; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE P1; POLYCYCLIC AROMATIC HYDROCARBON; TUMOR MARKER; UNCLASSIFIED DRUG;

ARTICLE; CANCER PREVENTION; CELL PROTECTION; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DISEASE MARKER; DNA ADDUCT; ENVIRONMENTAL EXPOSURE; GENE INACTIVATION; GENETIC ASSOCIATION; GENETIC EPIGENESIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; POLYMERASE CHAIN REACTION; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN METHYLATION; STAINING; STATISTICAL SIGNIFICANCE;

EID: 16244420106     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2004.08.028     Document Type: Article

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