Effects of sesame oil against after the onset of acetaminophen-induced acute hepatic injury in rats

Journal of Parenteral and Enteral Nutrition

Volumn 34, Issue 5, 2010, Pages 567-573

  Raj Mohan Chandrasekaran, Victor ^a   Chien, Se Ping ^b   Hsu, Dur Zong ^a   Chang, Yu Chung ^a   Liu, Ming Yie ^a,c  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b TAINAN UNIVERSITY OF TECHNOLOGY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

acetaminophen; aconitase; glutathione; reactive oxygen species; sesame oil

Indexed keywords

ACONITATE HYDRATASE; ALANINE AMINOTRANSFERASE; ANION; ASPARTATE AMINOTRANSFERASE; GLUTATHIONE; HYDROXYL RADICAL; LIPID; MITOCHONDRIAL ENZYME; PARACETAMOL; SESAME SEED OIL; SUPEROXIDE;

ACETAMINOPHEN INDUCED LIVER TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TOXIC HEPATITIS;

ACETAMINOPHEN; ACONITATE HYDRATASE; ALANINE TRANSAMINASE; ANALGESICS, NON-NARCOTIC; ANIMALS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; DRUG-INDUCED LIVER INJURY; GLUTATHIONE; HYDROXYL RADICAL; LIPID PEROXIDATION; LIVER; MALE; MITOCHONDRIA; NECROSIS; PHYTOTHERAPY; RATS; RATS, WISTAR; SESAME OIL; SESAMUM; SUPEROXIDES;

ANIMALIA; RATTUS; RATTUS NORVEGICUS; SESAMUM INDICUM;

EID: 78649820107     PISSN: 01486071     EISSN: None     Source Type: Journal    
DOI: 10.1177/0148607110362584     Document Type: Article

References (35)

1. Thomas S. Paracetamol (acetaminophen) poisoning. J Pharmacol Exp Ther. 1993 ; 60: 91-120.
2. Lesko SM, Mitchell AA The safety of acetaminophen and ibuprofen among children younger than two years old. Pediatrics. 1999 ; 104: e39.
3. Cranswick N., Coghlan D. Paracetamol efficacy and safety in children: the first 40 years. Am J Ther. 2000 ; 7: 135-141.
4. Proudfoot AT, Wright N. Acute paracetamol poisoning. Br Med J. 1970 ; 3: 557-558.
5. Hawton K., Fagg J., Simkin S., Bale E., Bond A. Deliberate self-harm in adolescents in Oxford, 1985-1995. J Adolesc. 2000 ; 23: 47-55.
6. Litovitz TL, Klein-Schwartz W., White S., et al. 1999 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2000 ; 18: 517-574.
7. Farrell G. Paracetamol-induced hepatotoxicity. In: Farrell G, ed. Drug-Induced Liver Diseases. New York, NY: Churchill Livingstone; 1994: 205-224.
8. Genter M., Liang H., Gu J., et al. Role of CYP2A5 and 2G1 in acetaminophen metabolism and toxicity in the olfactory mucosa of the cypa2(-/-) mouse. Biochem Pharmacol. 1998 ; 55: 1819-1826.
9. Sinclair J., Jeffery E., Wrighton S., Kostrubsky V., Szakacs J., Sinclair P. Alcohol-mediated increase in acetaminophen hepatotoxicity. Biochem Pharmacol. 1998 ; 55: 1557-1565.
10. Zaher H., Buters J., Ward J., et al. Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice. Toxicol Appl Pharmacol. 1998 ; 152: 193-199.
11. Shaw S., Herbert V., Colman N., Jayatilleke E. Effect of ethanol-generated free radicals on gastric intrinsic factor and glutathione. Alcohol. 1990 ; 7: 153-157.
12. Terneus MV, Kiningham KK, Carpenter AB, Sullivan SB, Valentovic MA Comparison of S-Adenosyl-L-methionine and N-acetylcysteine protective effects on acetaminophen hepatic toxicity. J Pharmacol Exp Ther. 2007 ; 320: 99-107.
13. Sugano M., Akimoto KA Multifunctional gift from nature. J Chin Nutr Soc. 1993 ; 18: 1-11.
14. Hsu DZ, Liu MY Sesame oil protects against lipopolysaccharide-stimulated oxidative stress in rats. Crit Care Med. 2004 ; 32: 227-231.
15. Chandrasekaran VR, Wan CH, Liu LL, Hsu DZ, Liu MY Effect of sesame oil against acetaminophen-induced oxidative hepatic damage in rats. Shock. 2008 ; 30: 217-221.
16. Bancroft JD, Cook BC Manual of Histological Techniques. Edinburgh, UK: Churchill Livingstone; 1984.
17. Gaskill CL, Miller LM, Mattoon JS, et al. Liver histopathology and liver and serum alanine aminotransferase and alkaline phosphatase activities in epileptic dogs receiving phenobarbital. Vet Pathol. 2005 ; 42: 147-160.
18. Yegen BC, Alican I., Yalcin AS, Oktay S. Calcium channel blockers prevent stress-induced ulcers in rats. Agents Actions. 1992 ; 35: 130-134.
19. Frezza C., Cipolat S., Scorrano L. Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts. Nat Protoc. 2007 ; 2: 287-295.
20. Bray BJ, Rosengren RJ Retinol potentiates acetaminophen-induced hepatotoxicity in the mouse: mechanistic studies. Toxicol Appl Pharmacol. 2001 ; 173: 129-136.
21. Hinson JA, Reid AB, McCullough SS, James LP Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition. Drug Metabol Rev. 2004 ; 36: 805-822.
22. Masubuchi Y., Suda C., Horie T. Involvement of mitochondrial permeability transition in acetaminophen-induced liver injury in mice. J Hepatol. 2005 ; 42: 110-116.
23. Bajt ML, Knight TR, Lemasters JJ, Jaeschke H. Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: Protection by N-acetyl cysteine. Toxicol Sci. 2004 ; 80: 343-349.
24. Jaeschke H., Bajt ML Intracellular signalling mechanism of acetaminophen-induced liver cell death. Toxicol Sci. 2006 ; 89: 31-41.
25. Beinert H., Kennedy MC Aconitase, a two-faced protein: enzyme and iron regulatory factor. FASEB J. 1993 ; 7: 1442-1449.
26. Hausladen A., Fridovich I. Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not. J Biol Chem. 1994 ; 47: 29405-29408.
27. Chandrasekaran VR, Hsu DZ, Liu MY The protective effect of sesamol against mitochondrial oxidative stress and hepatic injury in acetaminophen-overdosed rats. Shock. 2009 ; 32: 89-93.
28. Liochev SI, Fridovich I. The relative importance of HO* and ONOO- in mediating the toxicity of O*-. Free Radic Biol Med. 1999 ; 26: 777-778.
29. Kogan MD, Pappas G., Yu SM, Kotelchuck M. Over-the-counter medication use among US preschool-age children. JAMA. 1994 ; 272: 1025-1030.
30. James LP, Mayeux PR, Hinson JA Acetaminophen-induced hepatotoxicity. Drug Metab Dispos. 2003 ; 31: 1499-1506.
31. Larson AM Acetaminophen hepatotoxicity. Clin Liver Dis. 2007 ; 11: 525-548.
32. Simon JE, Chadwick AF, Craker LE Herbs: An indexed bibliography, 1971-1980. In: Hamden CT, ed. The Scientific Literature on Selected Herbs and Aromatic and Medicinal Plants of the Temperate Zone. Archon Books; 1984: 770. Available at: http://www.hort.purdue.edu/newcrop/med-aro/factsheets/SESAME.html. Accessed March 18, 2009.
33. Chavali SR, Utsunomiya T., Forse RA Increased survival after cecal ligation and puncture in mice consuming diets enriched with sesame seed oil. Crit Care Med. 2001 ; 29: 140-143.
34. Fukuda Y. Food chemical studies on the antioxidants in sesame seed. Nippon Shokuhin Kogyo Gakkaishi. 1990 ; 37: 484-492.
35. Kang MH, Katsuzaki H., Osawa T. Inhibition of 2,2′-azobis(2,4- dimethylvaleronitrile)-induced lipid peroxidation by sesaminols. Lipids. 1998 ; 33: 1031-1036.