Digitoxin activates EGR1 and synergizes with paclitaxel on human breast cancer cells

Journal of Carcinogenesis

Volumn 9, Issue , 2010, Pages

  Einbond, Linda ^a   Wu, Hsan Au ^a,b   Su, Tao ^a   Chang, Tangel ^a,c   Panjikaran, Maya ^a,d   Wang, Xiaomei ^a   Goldsberry, Sarah ^a,e  

^a Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

^d REGENERON PHARMACEUTICALS INC   (United States)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cardiac glycosides; microarrays; paclitaxel; stress response; synergy

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANGIOMOTIN LIKE 2; AT RICH INTERACTIVE DOMAIN 5B; B CELL TRANSLOCATION GENE 1 PROTEIN; CALMEGIN; CDC LIKE KINASE 3; CORNEODESMOSIN; DESMOPLAKIN; DIGITOXIN; EARLY GROWTH RESPONSE FACTOR 1; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EUKARYOTIC TRANSLATION INITIATION FACTOR 2B; INITIATION FACTOR 2; INOSITOL HEXAPHOSPHATE KINASE 2; KERATIN 23; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NUCLEAR RECEPTOR NUR77; PACLITAXEL; POTASSIUM VOLTAGE GATED CHANNEL; PROTEIN; PROTEIN P21; RAR RELATED ORPHAN RECEPTOR A; RETICULON 1; RING FI NGER PROTEIN 14; S6 KINASE; THIOREDOXIN REDUCTASE 3; UBIQUITIN SPECIFIC PROTEASE 34; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZINC FI NGER PROTEIN 297B; ZINC FI NGER PROTEIN 335;

ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL PROLIFERATION; DRUG POTENTIATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

EID: 78649804109     PISSN: 09746773     EISSN: 14773163     Source Type: Journal    
DOI: 10.4103/1477-3163.72578     Document Type: Article

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