Liposomal pravastatin inhibits tumor growth by targeting cancer-related inflammation

Journal of Controlled Release

Volumn 148, Issue 3, 2010, Pages 303-310

  Coimbra, Maria ^a   Banciu, Manuela ^a,b   Fens, Marcel H A M ^a   De Smet, Lieselotte ^a   Cabaj, Magda ^a   Metselaar, Josbert M ^a   Storm, Gert ^a   Schiffelers, Raymond M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b BABE BOLYAI UNIVERSITY   (Romania)

Author keywords

Angiogenesis; Cancer; Inflammation; Liposome; MHC class I; Statin

Indexed keywords

ANGIOGENESIS; CANCER; CLASS I; INFLAMMATION; STATIN;

CHOLESTEROL; ENDOTHELIAL CELLS; ENZYME ACTIVITY; GROWTH KINETICS; LIPOSOMES; MACROPHAGES; PATHOLOGY; PHOSPHOLIPIDS; PROTEINS;

TUMORS;

CHOLESTEROL; LIPOSOME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PRAVASTATIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL TYPE; CELL VIABILITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG TISSUE LEVEL; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; LIPID METABOLISM; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TUMOR CELL;

ANGIOGENIC PROTEINS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTICHOLESTEREMIC AGENTS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CYTOKINES; GENES, MHC CLASS I; HUMANS; INFLAMMATION; LIPID METABOLISM; LIPOSOMES; MALE; MICE; MICE, INBRED C57BL; NEOPLASMS; PRAVASTATIN;

EID: 78649802092     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.09.011     Document Type: Article

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