Structural studies on the enzyme complex isopropylmalate isomerase (LeuCD) from Mycobacterium tuberculosis

Proteins: Structure, Function and Bioinformatics

Volumn 79, Issue 1, 2011, Pages 35-49

  Manikandan, Karuppasamy ^a,b   Geerlof, Arie ^c   Zozulya, Alexey V ^d   Svergun, Dmitri I ^a   Weiss, Manfred S ^a  

^a DESY   (Germany)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d SYNCHROTRON SOLEIL   (France)

Author keywords

Isopropylmalate isomerase; LeuC; Leucine biosynthesis; LeuD; Tuberculosis; X ray crystallography

Indexed keywords

2 ISOPROPYLMALIC ACID; BACTERIAL DNA; BACTERIAL ENZYME; GENOMIC DNA; ISOMERASE; ISOPROPYLMALATE ISOMERASE; LEUCINE; MALIC ACID ISOPROPYL ESTER; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; LIGHT SCATTERING; MOLECULAR CLONING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OPEN READING FRAME; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STABILITY; X RAY CRYSTALLOGRAPHY;

ACONITATE HYDRATASE; AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; ISOMERASES; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; SCATTERING, SMALL ANGLE; STRUCTURAL HOMOLOGY, PROTEIN; X-RAY DIFFRACTION;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

EID: 78649784551     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22856     Document Type: Article

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