-
1
-
-
0030988217
-
Structure-function aspects in the nitric oxide synthases
-
Steuhr DJ. Structure-function aspects in the nitric oxide synthases. Annu Rev Pharmacol Toxicol 1997;37:339-359.
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 339-359
-
-
Steuhr, D.J.1
-
3
-
-
33751104228
-
Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression
-
Searles CD. Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression. Am J Physiol Cell Physiol 2006;291:C803-C816.
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Searles, C.D.1
-
4
-
-
1542373723
-
Endothelial nitric oxide synthase: A new paradigm for gene regulation in the injured blood vessel
-
Tai SC, Robb GB, Marsden PA. Endothelial nitric oxide synthase: a new paradigm for gene regulation in the injured blood vessel. Arterioscler Thromb Vasc Biol 2004;24:405-412.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 405-412
-
-
Tai, S.C.1
Robb, G.B.2
Marsden, P.A.3
-
5
-
-
0030843573
-
Estrogen upregulates endothelial nitric oxide synthase gene expression in fetal pulmonary artery endothelium
-
MacRitchie AN, Jun SS, Chen Z, German Z, Yuhanna IS, Sherman TS et al. Estrogen upregulates endothelial nitric oxide synthase gene expression in fetal pulmonary artery endothelium. Circ Res 1997;81:355-362.
-
(1997)
Circ Res
, vol.81
, pp. 355-362
-
-
MacRitchie, A.N.1
Jun, S.S.2
Chen, Z.3
German, Z.4
Yuhanna, I.S.5
Sherman, T.S.6
-
6
-
-
0033566864
-
Signal transduction of eNOS activation
-
Fleming I, Busse R. Signal transduction of eNOS activation. Cardiovasc Res 1999;43:532-541.
-
(1999)
Cardiovasc Res
, vol.43
, pp. 532-541
-
-
Fleming, I.1
Busse, R.2
-
7
-
-
10344237581
-
Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha
-
Lu Q, Pallas DC, Surks HK, Baur WE, Mendelsohn ME, Karas RH. Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha. Proc Natl Acad Sci USA 2004;101:17126-17131.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17126-17131
-
-
Lu, Q.1
Pallas, D.C.2
Surks, H.K.3
Baur, W.E.4
Mendelsohn, M.E.5
Karas, R.H.6
-
8
-
-
0037231474
-
Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells
-
Calnek DS, Mazzella L, Roser S, Roman J, Hart CM. Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells. Arterioscler Thromb Vasc Biol 2003;23:52-57.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 52-57
-
-
Calnek, D.S.1
Mazzella, L.2
Roser, S.3
Roman, J.4
Hart, C.M.5
-
9
-
-
1542652475
-
Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: Evidence for involvement of peroxisome proliferator-activated receptor (PPAR) gamma-dependent and PPARgamma-independent signaling pathways
-
Cho DH, Choi YJ, Jo SA, Jo I. Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: evidence for involvement of peroxisome proliferator-activated receptor (PPAR) gamma-dependent and PPARgamma-independent signaling pathways. J Biol Chem 2004;279:2499-2506.
-
(2004)
J Biol Chem
, vol.279
, pp. 2499-2506
-
-
Cho, D.H.1
Choi, Y.J.2
Jo, S.A.3
Jo, I.4
-
10
-
-
24144448954
-
Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms
-
Polikandriotis JA, Mazzella LJ, Rupnow HL, Hart CM. Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms. Arterioscler Thromb Vasc Biol 2005;25:1810-1816.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1810-1816
-
-
Polikandriotis, J.A.1
Mazzella, L.J.2
Rupnow, H.L.3
Hart, C.M.4
-
11
-
-
23244465468
-
Upregulation of nitric oxide production in vascular endothelial cells by all-trans retinoic acid through the phosphoinositide 3-kinase/Akt pathway
-
Uruno A, Sugawara A, Kanatsuka H, Kagechika H, Saito A, Sato K et al. Upregulation of nitric oxide production in vascular endothelial cells by all-trans retinoic acid through the phosphoinositide 3-kinase/Akt pathway. Circulation 2005;112:727-736.
-
(2005)
Circulation
, vol.112
, pp. 727-736
-
-
Uruno, A.1
Sugawara, A.2
Kanatsuka, H.3
Kagechika, H.4
Saito, A.5
Sato, K.6
-
12
-
-
0033591297
-
Identification of a nuclear receptor for bile acids
-
Makishima M, Okamoto AY, Repa JJ, Tu H, Learned RM, Luk A et al. Identification of a nuclear receptor for bile acids. Science 1999;284:1362-1365.
-
(1999)
Science
, vol.284
, pp. 1362-1365
-
-
Makishima, M.1
Okamoto, A.Y.2
Repa, J.J.3
Tu, H.4
Learned, R.M.5
Luk, A.6
-
13
-
-
0033026760
-
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
-
Wang H, Chen J, Hollister K, Sowers LC, Forman BM. Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol Cell 1999;3:543-553.
-
(1999)
Mol Cell
, vol.3
, pp. 543-553
-
-
Wang, H.1
Chen, J.2
Hollister, K.3
Sowers, L.C.4
Forman, B.M.5
-
14
-
-
0033591387
-
Bile acids: Natural ligands for an orphan nuclear receptor
-
Parks DJ, Blanchard SG, Bledsoe RK, Chandra G, Consler TG, Kliewer SA et al. Bile acids: natural ligands for an orphan nuclear receptor. Science 1999;284:1365-1368.
-
(1999)
Science
, vol.284
, pp. 1365-1368
-
-
Parks, D.J.1
Blanchard, S.G.2
Bledsoe, R.K.3
Chandra, G.4
Consler, T.G.5
Kliewer, S.A.6
-
15
-
-
0036668184
-
Bile acid regulation of gene expression: Roles of nuclear hormone receptors
-
Chiang JY. Bile acid regulation of gene expression: roles of nuclear hormone receptors. Endocr Rev 2002;23:443-463.
-
(2002)
Endocr Rev
, vol.23
, pp. 443-463
-
-
Chiang, J.Y.1
-
16
-
-
0034632762
-
Identification of a chemical tool for the orphan nuclear receptor FXR
-
Maloney PR, Parks DJ, Haffner CD, Fivush AM, Chandra G, Plunket KD et al. Identification of a chemical tool for the orphan nuclear receptor FXR. J Med Chem 2000;43:2971-2974.
-
(2000)
J Med Chem
, vol.43
, pp. 2971-2974
-
-
Maloney, P.R.1
Parks, D.J.2
Haffner, C.D.3
Fivush, A.M.4
Chandra, G.5
Plunket, K.D.6
-
17
-
-
4143056853
-
Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid
-
Pellicciari R, Costantino G, Camaioni E, Sadeghpour BM, Entrena A, Willson TM et al. Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid. J Med Chem 2004;47:4559-4569.
-
(2004)
J Med Chem
, vol.47
, pp. 4559-4569
-
-
Pellicciari, R.1
Costantino, G.2
Camaioni, E.3
Sadeghpour, B.M.4
Entrena, A.5
Willson, T.M.6
-
18
-
-
9944247695
-
Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism
-
Eloranta JJ, Kullak-Ublick GA. Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism. Arch Biochem Biophys 2005;433:397-412.
-
(2005)
Arch Biochem Biophys
, vol.433
, pp. 397-412
-
-
Eloranta, J.J.1
Kullak-Ublick, G.A.2
-
19
-
-
85047694456
-
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
-
Watanabe M, Houten SM, Wang L, Moschetta A, Mangelsdorf DJ, Heyman RA et al. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J Clin Invest 2004;113:1408-1418.
-
(2004)
J Clin Invest
, vol.113
, pp. 1408-1418
-
-
Watanabe, M.1
Houten, S.M.2
Wang, L.3
Moschetta, A.4
Mangelsdorf, D.J.5
Heyman, R.A.6
-
20
-
-
32244447570
-
Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice
-
Zhang Y, Lee FY, Barrera G, Lee H, Vales C, Gonzalez FJ et al. Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice. Proc Natl Acad Sci USA 2006;103:1006-1011.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1006-1011
-
-
Zhang, Y.1
Lee, F.Y.2
Barrera, G.3
Lee, H.4
Vales, C.5
Gonzalez, F.J.6
-
21
-
-
33645531297
-
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice
-
Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M et al. The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice. J Biol Chem 2006;281: 11039-11049.
-
(2006)
J Biol Chem
, vol.281
, pp. 11039-11049
-
-
Cariou, B.1
van Harmelen, K.2
Duran-Sandoval, D.3
van Dijk, T.H.4
Grefhorst, A.5
Abdelkarim, M.6
-
22
-
-
1542513682
-
Expression and activation of the farnesoid X receptor in the vasculature
-
Bishop-Bailey D, Walsh DT, Warner TD. Expression and activation of the farnesoid X receptor in the vasculature. Proc Natl Acad Sci USA 2004;101:3668-3673.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3668-3673
-
-
Bishop-Bailey, D.1
Walsh, D.T.2
Warner, T.D.3
-
23
-
-
33644861794
-
Downregulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells
-
He F, Li J, Mu Y, Kuruba R, Ma Z, Wilson A et al. Downregulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells. Circ Res 2006;98:192-199.
-
(2006)
Circ Res
, vol.98
, pp. 192-199
-
-
He, F.1
Li, J.2
Mu, Y.3
Kuruba, R.4
Ma, Z.5
Wilson, A.6
-
24
-
-
0035853057
-
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
-
Xie W, Radominska-Pandya A, Shi Y, Simon CM, Nelson MC, Ong ES et al. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci USA 2001;98:3375-3380.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3375-3380
-
-
Xie, W.1
Radominska-Pandya, A.2
Shi, Y.3
Simon, C.M.4
Nelson, M.C.5
Ong, E.S.6
-
25
-
-
0036589824
-
Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes
-
Kocarek TA, Shenoy SD, Mercer-Haines NA, Runge-Morris M. Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes. J Pharmacol Toxicol Methods 2002;47:177-187.
-
(2002)
J Pharmacol Toxicol Methods
, vol.47
, pp. 177-187
-
-
Kocarek, T.A.1
Shenoy, S.D.2
Mercer-Haines, N.A.3
Runge-Morris, M.4
-
26
-
-
0023228640
-
Endotoxin increases superoxide dismutase in cultured bovine pulmonary endothelial cells
-
Shiki Y, Meyrick BO, Brigham KL, Burr IM. Endotoxin increases superoxide dismutase in cultured bovine pulmonary endothelial cells. Am J Physiol 1987;252:C436-C440.
-
(1987)
Am J Physiol
, vol.252
-
-
Shiki, Y.1
Meyrick, B.O.2
Brigham, K.L.3
Burr, I.M.4
-
27
-
-
34547475143
-
Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor
-
Gong H, Guo P, Zhai Y, Zhou J, Uppal H, Jarzynka MJ et al. Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor. Mol Endocrinol 2007;21:1781-1790.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1781-1790
-
-
Gong, H.1
Guo, P.2
Zhai, Y.3
Zhou, J.4
Uppal, H.5
Jarzynka, M.J.6
-
28
-
-
4143100140
-
-
Li J, Ma Z, Tang ZL, Stevens T, Pitt B, Li S. CpG DNA-mediated immune response in pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol 2004;287:L552-L558.
-
Li J, Ma Z, Tang ZL, Stevens T, Pitt B, Li S. CpG DNA-mediated immune response in pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol 2004;287:L552-L558.
-
-
-
-
29
-
-
9144231188
-
A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification
-
Saini SP, Sonoda J, Xu L, Toma D, Uppal H, Mu Y et al. A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification. Mol Pharmacol 2004;65:292-300.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 292-300
-
-
Saini, S.P.1
Sonoda, J.2
Xu, L.3
Toma, D.4
Uppal, H.5
Mu, Y.6
-
30
-
-
33746834460
-
Bile acids induce adhesion molecule expression in endothelial cells through activation of reactive oxygen species, NF-kappaB, and p38
-
Qin P, Tang X, Elloso MM, Harnish DC. Bile acids induce adhesion molecule expression in endothelial cells through activation of reactive oxygen species, NF-kappaB, and p38. Am J Physiol Heart Circ Physiol 2006;291:H741- H747.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
-
-
Qin, P.1
Tang, X.2
Elloso, M.M.3
Harnish, D.C.4
-
31
-
-
85047682066
-
NUBIScan, an in silico approach for prediction of nuclear receptor response elements
-
Podvinec M, Kaufmann MR, Handschin C, Meyer UA. NUBIScan, an in silico approach for prediction of nuclear receptor response elements. Mol Endocrinol 2002;16:1269-1279.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 1269-1279
-
-
Podvinec, M.1
Kaufmann, M.R.2
Handschin, C.3
Meyer, U.A.4
-
32
-
-
0034616147
-
Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor
-
Laffitte BA, Kast HR, Nguyen CM, Zavacki AM, Moore DD, Edwards PA. Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor. J Biol Chem 2000;275:10638-10647.
-
(2000)
J Biol Chem
, vol.275
, pp. 10638-10647
-
-
Laffitte, B.A.1
Kast, H.R.2
Nguyen, C.M.3
Zavacki, A.M.4
Moore, D.D.5
Edwards, P.A.6
-
33
-
-
0035834769
-
Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor
-
Song CS, Echchgadda I, Baek BS, Ahn SC, Oh T, Roy AK et al. Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor. J Biol Chem 2001;276:42549-42556.
-
(2001)
J Biol Chem
, vol.276
, pp. 42549-42556
-
-
Song, C.S.1
Echchgadda, I.2
Baek, B.S.3
Ahn, S.C.4
Oh, T.5
Roy, A.K.6
-
34
-
-
0037169551
-
Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor
-
Kast HR, Goodwin B, Tarr PT, Jones SA, Anisfeld AM, Stoltz CM et al. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor. J Biol Chem 2002;277:2908-2915.
-
(2002)
J Biol Chem
, vol.277
, pp. 2908-2915
-
-
Kast, H.R.1
Goodwin, B.2
Tarr, P.T.3
Jones, S.A.4
Anisfeld, A.M.5
Stoltz, C.M.6
-
35
-
-
0038491484
-
The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element
-
Prieur X, Coste H, Rodriguez JC. The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element. J Biol Chem 2003;278:25468-25480.
-
(2003)
J Biol Chem
, vol.278
, pp. 25468-25480
-
-
Prieur, X.1
Coste, H.2
Rodriguez, J.C.3
-
36
-
-
0031884157
-
Estrogens increase transcription of the human endothelial NO synthase gene: Analysis of the transcription factors involved
-
Kleinert H, Wallerath T, Euchenhofer C, Ihrig-Biedert I, Li H, Förstermann U. Estrogens increase transcription of the human endothelial NO synthase gene: analysis of the transcription factors involved. Hypertension 1998;31:582-588.
-
(1998)
Hypertension
, vol.31
, pp. 582-588
-
-
Kleinert, H.1
Wallerath, T.2
Euchenhofer, C.3
Ihrig-Biedert, I.4
Li, H.5
Förstermann, U.6
-
37
-
-
0037772382
-
Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric oxide synthase
-
Bauer PM, Fulton D, Boo YC, Sorescu GP, Kemp BE, Jo H et al. Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric oxide synthase. J Biol Chem 2003;278:14841-14849.
-
(2003)
J Biol Chem
, vol.278
, pp. 14841-14849
-
-
Bauer, P.M.1
Fulton, D.2
Boo, Y.C.3
Sorescu, G.P.4
Kemp, B.E.5
Jo, H.6
-
38
-
-
20444409884
-
Receptor-regulated dynamic Snitrosylation of endothelial nitric-oxide synthase in vascular endothelial cells
-
Erwin PA, Lin AJ, Golan DE, Michel T. Receptor-regulated dynamic Snitrosylation of endothelial nitric-oxide synthase in vascular endothelial cells. J Biol Chem 2005;280:19888-19894.
-
(2005)
J Biol Chem
, vol.280
, pp. 19888-19894
-
-
Erwin, P.A.1
Lin, A.J.2
Golan, D.E.3
Michel, T.4
-
39
-
-
33947383769
-
The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells
-
Keitel V, Reinehr R, Gatsios P, Rupprecht C, Gorg B, Selbach O et al. The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells. Hepatology 2007;45:695-704.
-
(2007)
Hepatology
, vol.45
, pp. 695-704
-
-
Keitel, V.1
Reinehr, R.2
Gatsios, P.3
Rupprecht, C.4
Gorg, B.5
Selbach, O.6
-
40
-
-
33748098690
-
The hepatopulmonary syndrome
-
Palma DT, Fallon MB. The hepatopulmonary syndrome. J Hepatol 2006;45:617-625.
-
(2006)
J Hepatol
, vol.45
, pp. 617-625
-
-
Palma, D.T.1
Fallon, M.B.2
-
41
-
-
0025825673
-
Impaired pressor reactivity in cirrhosis: Evidence for a peripheral vascular defect
-
MacGilchrist AJ, Sumner D, Reid JL. Impaired pressor reactivity in cirrhosis: evidence for a peripheral vascular defect. Hepatology 1991;13:689-694.
-
(1991)
Hepatology
, vol.13
, pp. 689-694
-
-
MacGilchrist, A.J.1
Sumner, D.2
Reid, J.L.3
|