Possible role of vitamin E, coenzyme Q10 and rutin in protection against cerebral ischemia/reperfusion injury in irradiated rats

International Journal of Radiation Biology

Volumn 86, Issue 12, 2010, Pages 1070-1078

  Abd El Fattah, Amal A ^b   El Sawalhi, Maha M ^b   Rashed, Engy R ^a   El Ghazaly, Mona A ^a  

^a NATIONAL CENTER FOR RADIATION RESEARCH AND TECHNOLOGY   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

radiation; cerebral ischemia reperfusion; coenzyme Q10; rutin; vitamin E

Indexed keywords

ALPHA TOCOPHEROL; CALCIUM; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; MALONALDEHYDE; RUTOSIDE; TUMOR NECROSIS FACTOR ALPHA; UBIDECARENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN; BRAIN ISCHEMIA; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; ENZYME ACTIVITY; GAMMA IRRADIATION; INFLAMMATION; IRRADIATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; WHOLE BODY RADIATION; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; BRAIN ISCHEMIA; GAMMA RAYS; GLUTATHIONE; INTERLEUKIN-1BETA; MALE; MALONDIALDEHYDE; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; RATS; RATS, WISTAR; REPERFUSION INJURY; RUTIN; TUMOR NECROSIS FACTOR-ALPHA; UBIQUINONE; VITAMIN E;

RATTUS; RATTUS NORVEGICUS;

EID: 78649747639     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553002.2010.501844     Document Type: Article

References (57)

1. Abou-Seif MA, El-Nagga MM, El-Far M, Ramadan M, Salah N. 2003. Amelioration of radiation-induced oxidative stress and biochemical alteration by SOD model compounds in pre-treated g-irradiated rats. Clinica Chimica Acta 337: 23-33.
2. Almaas R, Saugstad OD, Pleasure D, Rootwelt T. 2002. Neuronal formation of free radicals plays a minor role in hypoxic cell death in human NT2N neurons. Pediatric Research 51(2): 136-143.
3. Amantea D, Nappi G, Bernardi G, Bagetta G, Corasaniti MT. 2009. Postischemic brain damage: Pathophysiology and role of inflammatory mediators. The FEBS Journal. 276(1): 13-26.
4. Avrova NF, Shestak KI, Zakharova IO, Sokolova TV, Tyurina YY, Tyurin VA. 2000. The use of antioxidants to prevent glutamate-induced derangement of calcium ion metabolism in rat cerebral cortex synaptosomes. Neuroscience of Behavioural Physiology 30:535-541.
5. Beutler E, Duron O, Kelly BM. 1963. Improved method for the determination of blood glutathione. Journal of Laboratory and Clinical Medicine 61:882-888.
6. Brongholi K, Souza DG, Bainy ACD, Dafre AL, Tasca CI. 2006. Oxygen-glucose deprivation decreases glutathione levels and glutamate uptake in rat hippocampal slices. Brain Research 1083:211-218.
7. Chakraborti A, Gulati K, Basu Dev Banerjee B, Ray A. 2007. Possible involvement of free radicals in the differential neurobehavioral responses to stress in male and female rats. Behavioural Brain Research 179:321-325.
8. Chaudhary G, Sinha K, Gupta YK. 2003. Protective effect of exogenous administration of alpha-tocopherol in middle cerebral artery occlusion model of cerebral ischemia in rats. Fundamental and Clinical Pharmacology 17:703-707.
9. Cremer JE, Cunningham VJ, Partridge WM, Braun LD, Oldendrof WH. 1979. Kinetics of blood brain barrier transport of pyruvate, lactate and glucose in suckling, weanling and adult rats. Journal of Neurochemistry 3:439-455.
10. De Toledo SM, Asaad N, Venkatachalam P, Li L, Howell RW, Spitz DR. 2006. Adaptive responses to low-dose/low-dose-rate gamma rays in normal human fibroblasts: The role of growth architecture and oxidative metabolism. Radiation Research 166(6):849-857.
11. Dhanasekaran M, Ren J. 2005. The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus. Current Neurovascular Research 2:447-459.
12. Dvoretskii AI, Ivashko SV. 1987. Post-radiation changes in active transport in the CNS: Mg2\+,Ca2\+-ATPase [Abstract]. Radiobiologiia 27(4):547-548.
13. El-Ghazaly MA, Khayyal MT. 1995. The use of aqueous propolis extract against radiation-induced damage. Drugs under Experimental and Clinical Research 21(6):229-236.
14. Erol FS, Topsakal C, Ozveren MF, Kaplan M, Ilhan N, Ozercan IH et al. 2004. Protective effects of melatonin and vitamin E in brain damage due to gamma radiation: An experimental study. Neurosurgical Review 27:65-69.
15. Godbout JP, Berg BM, Krzyszton C, Johnson RW. 2005. atocopherol attenuates NF-kB activation and pro-inflammatory cytokine production in brain and improves recovery from lipopolysaccharide-induced sickness behavior. Journal of Neuroimmunology 169(12):97-105.
16. Harukuni I, Bhardwaj A. 2006. Mechanisms of brain injury after global cerebral ischemia. Neurologic Clinics 24:1-21.
17. Horakova L, Ondrejichova O, Uraz V, Lukovic L, Juranek I. 1992. Short cerebral ischemia and subsequent reperfusion and treatment with stobadine. Experientia 48:872-874.
18. Howell BF, McCane S, Schaffer R. 1979. Lactate to pyruvate or pyruvate to lactate assay for lactate dehydrogenase: a reexamination. Clinical Chemistry 25:269-272.
19. Hurtado O, De Cristó bal J, Sánchez V, Lizasoain I, Cárdenas A, Pereira MP, et al. 2003. Inhibition of glutamate release by delaying ATP fall accounts for neuroprotective effects of antioxidants in experimental stroke. The FASEB Journal 17(14):2082-2084.
20. Intiso D, Zarrelli MM, Lagioia G, Di Rienzo F, Checchia De Ambrosio C, Simone, P, Tonali P, Cioffi Dagger RP. 2004. Tumor necrosis factor alpha serum levels and inflammatory response in acute ischemic stroke patients. Neurological Sciences 24:390-396.
21. Kamalakkannan N, Stanely Mainzen Prince P. 2006. Rutin improves the antioxidant status in streptozotocin-induced diabetic rat tissues. Molecular and Cellular Biochemistry 293:211-219.
22. Khalil AA, Aziz FA, Hull JC. 2006. Reperfusion injury. Plastic and Reconstructive Surgery 117:1024-1033.
23. Kojima S, Matsuki O, Kinoshita I, Gonzalez TV, Shimura N, Kubodera A. 1997. Does small-dose g-ray radiation induce endogenous antioxidant potential in vivo? Biological & Pharmaceutical Bulletin 20(6):601-604.
24. Kosk-Kosicka D, Wawrzynow A, Roszczynska G. 1994. Stabilizing and destabilizing effects on plasma membrane Ca2\+-ATPase activity. Molecular and Cellular Biochemistry 139:1-9.
25. Kumari Naga K, Panigrahi M, Prakash Babu P. 2007. Changes in endogenous antioxidant enzymes during cerebral ischemia and reperfusion. Neurological Research 29(8):877-883.
26. Linard C, Marquette C, Mathieu J, Pennequin A, Clarencon D, Mathe D. 2004. Acute induction of inflammatory cytokine expression after g-irradiation in the rat: Effect of an NF-kB inhibitor. International Journal of Radiation Oncology, Biology, Physics 58:427-434.
27. Lipton P, Lobner D. 1990. Mechanisms of intracellular calcium accumulation in the CA1 region of rat hippocampus during anoxia in vitro. Stroke 21:60-64.
28. Long WK, Carson PE. 1961. Increased erythrocyte glutathione reductase activity in diabetes mellitus. Biochemical and Biophysical Research Communications 5:394-399.
29. Marquette C, Linard C, Galonnier M, Van Uye A, Mathieu J, Gourmelon P. 2003. IL-1beta, TNFalpha and IL-6 induction in the rat brain after partial-body irradiation: Role of vagal afferents. International Journal of Radiation Biology 79:777-785.
30. Martínez-Romero R, Cañuelo A, Martínez-Lara E, Hernández R, Del Moral ML, Pedrosa JA. Peinado MA, Siles E. 2006. Aging affects but does not eliminate the enzymatic antioxidative response to hypoxia/reoxygenation in cerebral cortex. Experimental Gerontolology 41(1):25-31.
31. Morshed KM, Nagpaul JP, Majumdar S, Amma MK. 1989. Kinetics of oral propylene glycol-induced acute hyperlactatemia. Biochemical Medicine and Metabolic Biology 42(2): 87-94.
32. Nakamura T, Minamisawa H, Katayama Y, Ueda M, Terashi A, Naka-mura K, Kudo Y. 1999. Increased intracellular Ca2\+ concentration in the hippocampal CA1 area during global ischemia and reperfusion in the rat: A possible cause of delayed neuronal death. Neuroscience 88:57-67.
33. Niu KC, Lin KC, Yang CY, Lin MT. 2003. Protective effects of alpha-tocopherol and mannitol in both circulatory shock and cerebral ischaemia injury in rat heatstroke. Clinical and Experimental Pharmacology and Physiology 30:745-751.
34. Nosov AV, Ivnitsky YY, Malakhovsky VN. 1999. Metabolic correction of cerebral radiation syndrome. Radiation Research 152(5):523-529.
35. Onem G, Aral E, Enli Y, Egashira N, Iwasaki K, Hidaka R Ozcan AV, Sacar M, Bir LS, Baltalarli A, Baycu C. 2006. Neuroprotective effects of L-carnitine and vitamin E alone or in combination against ischemia-reperfusion injury in rats. Journal of Surgical Research 131:124-130.
36. Ostrowski RP. 2000. Effect of coenzyme-Q10 on biochemical and morphological changes in experimental ischemia in the rat brain. Brain Research Bulletin 53(4):399-407.
37. Ozbal S, Erbil G, Kocdor H, Tugyan K, Pekcetin C, Ozogul C. 2008. The effects of selenium against cerebral ischemiareperfusion injury in rats. Neuroscience Letters 438:265-269.
38. Paglia DE, Valentine WN. 1967. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. Journal of Laboratory and Clinical Medicine 70:158-169.
39. Park HH, Lee S, Son HY, Park SB, Kim MS, Choi EJ, Singh TS, Ha JH, Lee MG, Kim JE, Hyun MC, Kwon TK, Kim YH, Kim SH. 2008. Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells. Archives of Pharmacal Research 31:1303-1311.
40. Pu F, Mishima K, Irie K, Motohashi K, Tanaka Y, Orito K. Sakagami H, Satoh Y, Izumi T, Majima M. 2007. Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats. Journal of Pharmacological Sciences 104:329-334.
41. Rothman SM, Olney JW. 1986. Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Annals of Neurology 19:105-111.
42. Schurr A, Rigor BM. 1992. The mechanism of cerebral hypoxicischemic damage. Hippocampus 2:221-228.
43. Seif-El-Nasr M, Atia AS, Abdelsalam RM. 2008. Effect of MAOB inhibition against ischemia-induced oxidative stress in the rat brain. Comparison with a rational antioxidant. Arzneimittel Forschung 58:160-167.
44. Sener G, Kabasakal L, Atasoy BM, Erzik C, Velio-glu-O-günç A, Cetinel S. 2006. Ginkgo biloba extract protects against ionizing radiation-induced oxidative organ damage in rats. Pharmacological Research 53(3):241-252. (Pubitemid 43247536)
45. Sezen O, Ertekin MV, Demircan B, Karslioglu I, Erdogan F, Kocer I Calik I, Gepdiremen A. 2008. Vitamin E and L-carnitine, separately or in combination, in the prevention of radiation-induced brain and retinal damages. Neurosurgical Review 31:205-213.
46. Shaheen AA, Abd-El-Fattah AA, Seif-El-Nasr M. 1996. Influence of verapamil on the efficacy of vitamin E in preventing the ischemia/reperfusion biochemical dearrangement in cerebral cortex of rat. Arzneimittel Forschung 46(7):670-673.
47. Siesjo BK, Katura KI, Kristian T, Li P. 1996. Molecular mechanism of acidosis-mediated damage. Acta Neurochirurgica 66:8-14.
48. Starkov AA, Chinopoulos C, Fiskum G. 2004. Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. Cell Calcium 36:257-264. (Pubitemid 38992351)
49. Stys PK, Waxman SG, Ransom BR. 1991. Na\+-Ca2\+ exchanger mediates Ca2\+ influx during anoxia in mammalian central nervous system white matter. Annals of Neurology 30:375-380.
50. Subramania RS. 1995. Storage and preservation of blood and urine for trace element analysis: A review. Biological Trace Element Research 49:187-210.
51. Tofilon PJ, Fike JR. 2000. The radioresponse of the central nervous system: A dynamic process. Radiation Research 153:357-370.
52. Torregrosa G, Burguete MC, Pérez-Asensio FJ, Salom JB, Gil JV, Alborch E. 2003. Pharmacological profile of phytoestrogens in cerebral vessels: In vitro study with rabbit basilar artery. European Journal ofPharmacology 482(1-3):227-234.
53. Uchiyama M, Mihara M. 1978. Determination ofmalonaldehyde precursor in tissues by thiobarbituric acid test. Analytical Biochemistry 86(1):271-278.
54. + antagonist drugs. In: Krieglstein J, Oberpichler H, editors. Pharmacology of cerebral ischemia, Stuttgart: Wissenschaftlische Verlagsge-sellschaft. pp 311-315.
55. Weiss JF, Landauer MR. 2003. Protection against ionizing radiation by antioxidant nutrients and phytochemicals. Toxicology 189:1-20.
56. Yildirim O, Comoglu S, Yardimci S, Akmansu M, Bozkurt G, Surucu S. 2008. Preserving effects of melatonin on the levels of glutathione and malondialdehyde in rats exposed to irradiation. General Physiology and Biophysics 27:32-37.
57. Yousuf S, Atif F, Hoda N, Ahmad M, Saleem S, Ishrat T. Khan MB, Ahmad AS, Islam F. 2007. Oral supplementation of Majun Baladar ameliorates antioxidant enzyme activities in cerebral ischaemic damage. Basic and Clinical Pharmacology and Toxicology 101:246-253.