The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals

Biochemical Journal

Volumn 432, Issue 1, 2010, Pages 165-172

  Thierbach, René ^a,b,e   Drewes, Gunnar ^b   Fusser, Markus ^c   Voigt, Anja ^b,d   Kuhlow, Doreen ^d,e   Blume, Urte ^a,b   Schul, Tim J ^e,f   Reiche, Carina ^c   Glatt, Hansruedi ^d   Epe, Bernd ^c   Steinberg, Pablo ^a,b   Ristow, Michael ^d,e  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b UNIVERSITY OF POTSDAM   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^e FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

DNA base excision repair; Frataxin; Friedreich's ataxia; Iron sulfur cluster; Oxidative stress; Tumorigenesis

Indexed keywords

BASE EXCISION REPAIRS; FRATAXIN; FRIEDREICH'S ATAXIA; IRON-SULFUR CLUSTER; TUMORIGENESIS;

BIOCHEMISTRY; BIOINFORMATICS; CELL CULTURE; DNA; ENZYMES; GENES; LIVER; MAMMALS; MITOCHONDRIA; SULFUR; TUMORS;

REPAIR;

8 HYDROXYGUANINE; DNA BASE; FRATAXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; CELL CYCLE REGULATION; CELL ISOLATION; CELL STRAIN V 79; CHO CELL; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA DAMAGE; DNA MODIFICATION; DNA REPAIR; EXCISION REPAIR; FEMALE; FIBROBLAST; FRIEDREICH ATAXIA; GENE DISRUPTION; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; IMMUNOMODULATION; LIVER CELL; MAMMAL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROKARYOTE; SALMONELLA ENTERICA; SEROTYPE;

ANIMALS; CELL LINE; CELLS, CULTURED; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; FIBROBLASTS; FRIEDREICH ATAXIA; HEPATOCYTES; HUMANS; IRON-BINDING PROTEINS; IRON-SULFUR PROTEINS; LIVER NEOPLASMS; MAMMALS; MICE; MICE, KNOCKOUT; MUTATION; OXIDATIVE STRESS; PROKARYOTIC CELLS; SALMONELLA ENTERICA; TRANSFECTION;

EUKARYOTA; MAMMALIA; MURINAE; MUS; PROKARYOTA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM;

EID: 78649724334     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101116     Document Type: Article

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